Hepatobiliary Cancer

1. Front Matter

   Pages i-xviii

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2. Inefficiency of metastasis from colorectal carcinomas

   • Leonard Weiss

   Pages 1-11

3. Cytoreductive approach to treatment of multiple liver metastases

   • Paul H. Sugarbaker, Mark A. Steves

   Pages 13-20

4. Hepatoma registry of the western world

   • Jane I. Tsao, Horacio J. Asbun, Kevin S. Hughes, Sabas Abaubara, David A. August, Arturo Azurin et al.

   Pages 21-31

5. Resection of hepatic metastases from colorectal carcinoma

   • Horacio J. Asbun, Jane I. Tsao, Kevin S. Hughes

   Pages 33-41

6. Surgical management of hepatic metastases from large bowel cancer

   • Bernard Nordlinger, Pierre Balladur

   Pages 43-51

7. Repeat resections of primary hepatic malignancies

   • Bernard Nordlinger, Philippe Wind

   Pages 53-56

8. Repeat resections for recurrent colorectal liver metastases

   • Bernard Nordlinger, J.-C. Vaillant

   Pages 57-61

9. Liver transplantation as an option for primary malignancy

   • Henri Bismuth, Laurence Chiche

   Pages 63-73

10. Surgical treatment of cholangiocarcinoma

    • Leslie H. Blumgart, Steven C. Stain

    Pages 75-96

11. Treatment of gallbladder cancer

    • Harold J. Wanebo, Michael P. Vezeridis

    Pages 97-109

12. Use of clamps in hepatobiliary surgery

    • Kenneth P. Ramming

    Pages 111-119

13. Chemotherapy after hepatic resection of colorectal metastases

    • M. Margaret Kemeny

    Pages 121-128

14. Radiological evaluation of metastases to the liver: The Emory Experience

    • Rendon C. Nelson

    Pages 129-146

15. Hepatic vascular exclusion for hepatic resection

    • James A. Knol, Frederick E. Eckhauser

    Pages 147-155

16. Radiologic evaluation and treatment of gallbladder and biliary tree carcinoma

    • Ann Archer, Keith Horton

    Pages 157-183

17. Repeat liver resections from colorectal metastasis

    • Vicente Fernández-Trigo, Falah Shamsa, Joaquin Aldrete, Roland Andersson, Jean-Pierre Arnaud, Roberto Bergamaschi et al.

    Pages 185-196

18. Intraoperative ultrasound and liver tumors

    • Steven T. Brower, Myron Schwartz, Charles Miller

    Pages 197-220

19. Parenchymal dissection techniques

    • W. John B. Hodgson

    Pages 221-230

20. Surgical resection and transplantation for hepatocellular carcinoma

    • Bernard Langer, Paul D. Greig, Bryce R. Taylor

    Pages 231-240

When one deals with cancer, the hepatobiliary malignancies present a chal­ lenge to the oncologists that can be characterized as a series of unsolved clinical and biological dilemmas. Liver metastases from colorectal and other gastrointestinal malignancies, hepatocellular carcinoma, cholangiocar­ cinoma, and gall bladder cancer present an array of problems but have two features in common. These are high morbidity and mortality with an overall poor result from treatment. Why is it that hepatobiliary cancer carries with it such a dismal prognosis? First of all, these diseases present, for the most part, in an advanced state. To this point in time the oncologist has had no help from early diagnosis or screening. Only the occasional patient followed by ultrasound or a tumor marker has the disease diagnosed in an asymptomatic state. By the time these diseases become symptomatic, curative treatment options have usually disappeared. Evolution has placed the liver in a protected position in order to avoid injury to the soft parenchyma. As with many other internal organs, the nerve supply is extremely limited. These two anatomic features result in a great lack of early warning signs of cancer.

• carcinoma
• clinical trial
• liver
• liver transplantation
• liver tumor
• metastasis
• morbidity
• mortality
• surgery
• transplantation
• tumor
• abdominal surgery

• The Cancer Institute, Washington Hospital Center, USA

  Paul H. Sugarbaker

Policies and ethics