Advances in Modelling and Clinical Application of Intravenous Anaesthesia

1. Front Matter

   Pages i-xiii

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2. Pharmacokinetic and Dynamic Modelling

   1. Front Matter

      Pages 1-1

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   2. Basic Pharmacokinetic Principles for Intravenous Anaesthesia

      • Frank H. M. Engbers

      Pages 3-18

   3. Basic Concepts of Recirculatory Pharmacokinetic Modelling

      • Marije Reekers, Fred Boer, Jaap Vuyk

      Pages 19-26

   4. Recirculatory Pharmacokinetics

      • Thomas K. Henthorn

      Pages 27-33

   5. Response Surface Modelling of Drug Interactions

      • Charles Minto, Jaap Vuyk

      Pages 35-43

   6. Age Related Changes of the PK-PD of Intravenous Anaesthetics

      • Thomas W. Schnider, Charles F. Minto

      Pages 45-56

   7. Clinical Application of Pharmacokinetic and Pharmacodynamic Models

      • Valerie Billard

      Pages 57-70

   8. Gender Differences in Morphine Pharmacokinetics and Dynamics

      • Elise Sarton, Raymonda Romberg, Albert Dahan

      Pages 71-80

   9. Influence of Propofol on the Control of Breathing

      • Albert Dahan, Diederik J.F. Nieuwenhuijs, Erik Olofsen

      Pages 81-92

3. Monitoring and Clinical Application of Intravenous Anaesthesia

   1. Front Matter

      Pages 93-93

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   2. Bispectral Index Scale (BIS) Monitoring and Intravenous Anaesthesia

      • Jaap Vuyk, Martijn Mertens

      Pages 95-104

   3. Auditory Evoked Potentials

      • Stefan Schraag, Gavin NC Kenny

      Pages 105-113

   4. Functional Brain Imaging and Propofol Mechanisms of Action

      • Pierre Fiset

      Pages 115-121

   5. The Development and Future of Target Controlled Infusion

      • John B Glen

      Pages 123-133

   6. Awareness 1960 – 2002, Explicit Recall of Events During General Anaesthesia

      • Rolf H. Sandin

      Pages 135-147

   7. Sedation for Locoregional Anaesthesia

      • Armin Holas

      Pages 149-159

   8. Target-Controlled Infusion in Children

      • Xavier Viviand, Aurélie Bourgoin

      Pages 161-170

   9. Remifentanil for Cardiac Anaesthesia

      • Luc Barvais, Nicholas Sutcliffe

      Pages 171-187

4. Effect Sites of Analgesic and Anaesthetic Action

   1. Front Matter

      Pages 189-189

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Since its launch in 1998 the European Society for Intravenous Anaesthesia (EuroSIVA) has come a long way in providing educational material and supporting the research and clinical application of intravenous anaesthesia. After the first two annual meetings held in Barcelona and Amsterdam in 1998 and 1999, three other successful meetings took place in Vienna, Gothenburg and Nice in 2000, 2001 and 2002. Next to these main meetings, starting in the year 2000, a smaller winter meeting has been organised every last week of January in Crans Montana, Switzerland. Both the main summer and the winter meetings breathe the same atmosphere of sharing the latest on intravenous anaesthesia research in the presence of a friendly environment and good company. Since the first meetings the educational tools of EuroSIVA have increased in quantity and technical quality allowing digital slide and video presentation along with the use of the computer simulation program TIVAtrainer during the speaker sessions and the workshops. Furthermore, EuroSIVA now exploits a website www. eurosiva. org that allows for continuous exchange of information on intravenous anaesthesia, the TIVAtrainer, the EuroSIVA meetings and online registration for these meetings. The EuroSIVA is currently engaged in friendly contacts with the Asian Oceanic Society for Intravenous Anaesthesia (AOSIVA), the United Kingdom Society for Intravenous Anaesthesia (UKSIVA), the Korean Society for Intravenous Anaesthesia (KSIVA), the European Society of Anaesthesiology (ESA) and the International Society for Applied Pharmacology (ISAP).

• Infusion
• Sedation
• muscle
• pharmacology
• surgery

• Leiden University Medical Centre, Leiden, The Netherlands

  Jaap Vuyk

• University of Ulm, Ulm, Germany

  Stefan Schraag

Policies and ethics