Muscle Metabolism During Exercise

1. Front Matter

   Pages i-xvi

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2. Muscle Metabolism During Exercise in Man

   1. Muscle Metabolism During Exercise in Man

      • Erling Asmussen

      Pages 1-11

3. Adaptive Changes in Morphology and Enzymes of Skeletal Muscles

   1. Histochemical Effects of Contraction on Red and White Rat Muscle Fibres. Their Organization in the Motor Unit

      • Eric Kugelberg, Lars Edström

      Pages 13-19

   2. Reversal of Enzymatic Profiles and Capillary Supply of Muscle Fibers in Fast and Slow Muscles After Cross Innervation

      • Flaviu C. A. Romanul

      Pages 21-32

   3. Metabolic Differentiation of Distinct Muscle Types at the Level of Enzymatic Organization

      • Dirk Pette

      Pages 33-49

   4. Biochemical Adaptations to Endurance Exercise in Skeletal Muscle

      • J. O. Holloszy, L. B. Oscai, P. A. Molé, I. J. Don

      Pages 51-61

   5. Influence of Exercise on Electron Transport Capacity of Heart Mitochondria

      • Hans Kraus

      Pages 63-68

   6. Ultrastructural and Enzyme Changes in Muscles with Exercise

      • Philip D. Golinick, C. David Ianuzzo, Douglas W. King

      Pages 69-85

   7. Effects of Long-Term Exercise on Human Muscle Mitochondria

      • T. E. Morgan, L. A. Cobb, F. A. Short, R. Ross, D. R. Gunn

      Pages 87-95

   8. Effect of Physical Training on Ultrastructural Features in Human Skeletal Muscle

      • K.-H. Kiessling, K. Piehl, C.-G. Lundquist

      Pages 97-101

4. Energy Stores (Magnitude, Regulation and Interaction)

   1. Release of Substrates from Extramuscular Stores During Exercise

      1. Metabolic Role of Muscle

         • George F. Cahill Jr.

         Pages 103-109

      2. Adrenergic Neuro-Humoral Control of Lipolysis in Adipose Tissue

         • Sune Rosell, Kathryn Ballard

         Pages 111-117

      3. Role of Circulating Noradrenaline and Adrenaline

         • Jan Häggendal

         Pages 119-125

      4. The Liver as an Energy Source in Man During Exercise

         • Loring B. Howell

         Pages 127-141

      5. Liver Glycogen in Man. Effect of Different Diets and Muscular Exercise

         • E. Hultman, L. H. Nilsson

         Pages 143-151

   2. Uptake and Oxidation of Energy Rich Compounds in the Muscle During Exercise

      1. Metabolism of Free Fatty Acids and Ketone Bodies in Skeletal Muscle

         • L. Hagenfeldt, J. Wahren

         Pages 153-163

      2. Plasma Insulin Levels During Prolonged Exercise

         • E. D. R. Pruett

         Pages 165-175

      3. Glucose Uptake in Contracting, Isolated <u>In</u> <u>Situ</u> Dog Skeletal Muscle

         • N. S. Skinner Jr., J. C. Costin, B. Saltin, G. Vastagh

         Pages 177-187

      4. Glucose Metabolism During Exercise in Man

         • J. Wahren, G. Ahlborg, P. Felig, L. Jorfeldt

         Pages 189-203

      5. Interrelationship Between Amino Acid and Carbohydrate Metabolism During Exercise: The Glucose Alanine-Cycle

         • Philip Felig, John Wahren

         Pages 205-214

Howard G. Knuttgen of Biology, Boston University, 2 Cummington Department Street, Boston, 02215 Massachusetts, USA The relationship of the formation of lactate acid to skeletal muscle energy release in exercising humans was first explored by A. V. Hill and co-workers (2l, 22). The term "oxygen debt" was suggested by them to describe the excess oxygen consumption of recovery which they felt was closely related. A combination of their work and the earlier work of Krogh and Lindhard (35) re­ sulted at that time in the belief that a certain amount of energy release during the transition from rest to exercise was provided by a non-aerobic source, glycolysis. The resulting accumulation of lactic acid (as lactate) in the body required an extra con­ sumption during recovery for its oxidative removal. Jervell (24) subsequently showed that, in exercise, the greatest accumulation in blood took place during the first few minutes. He felt that the blood lactate increase was due to a shortage of oxygen during the transition period. The observation was also made for the first time that the increased level of lac­ tate due to exercise could be made to fall faster if mild exercise was employed by the subjects in place of sedentary recovery. The work of Margaria, Edwards and Dill (40) appeared in 1933. They observed that exercise (treadmill running) could be carried on at low levels without significant changes in resting levels of blood lactate.

• Recovery
• biology
• energy
• metabolism
• oxygen
• skeletal muscle
• Tree Biology

• Department of Clinical Physiology, Serafimerlasarettet, Karolinska Institutet, Stockholm, Sweden

  Bengt Pernow

• Department of Physiology, Gymnastik & Idrottshögskolan, Stockholm, Sweden

  Bengt Saltin

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