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Metabolic Compartmentation and Neurotransmission

Relation to Brain Structure and Function

  • Book
  • © 1975

Overview

Editors:
  1. Soll Berl

    1. Mt. Sinai School of Medicine, New York, USA

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  2. D. D. Clarke

    1. Fordham University, Bronx, USA

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    You can also search for this editor in PubMed   Google Scholar

  3. Diana Schneider

    1. Neurosciences Research Program, Boston, USA

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Part of the book series: NATO Science Series A: (NSSA, volume 6)

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Table of contents (40 chapters)

  1. Front Matter

    Pages i-xxiii
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  2. Glutamic Acid, a Putative Neurotransmitter of Cerebellar Granule Cells: Evidence from the Virally Induced Granuloprival Cerebellum

    • Solomon H. Snyder, Anne B. Young, Mary Lou Oster-Granite, Robert M. Herndon
    Pages 1-10

  3. Gamma-Aminobutyric and Glutamic Acids as Mammalian Central Transmitters

    • David R. Curtis
    Pages 11-36

  4. Neurochemical Evidence for Glycine as a Transmitter and a Model for Its Intrasynaptosomal Compartmentation

    • M. H. Aprison, E. C. Daly, R. P. Shank, W. J. McBride
    Pages 37-63

  5. Uptake and Localization of Transmitter Amino Acids in the Nervous System

    • L. L. Iversen, Fabienne Dick, J. S. Kelly, F. Schon
    Pages 65-89

  6. Glial Transport of Amino Acid Neurotransmitter Candidates

    • Fritz A. Henn
    Pages 91-97

  7. The Localization of Glutamate Decarboxylase, Choline Acetyltransferase, and Aromatic Amino Acid Decarboxylase in Mammalian and Invertebrate Nervous Tissue

    • F. Fonnum
    Pages 99-122

  8. Uptake of Transmitter Candidates as an Approach to their Localization

    • Jon Storm-Mathisen
    Pages 123-135

  9. The Olfactory Pathway as a Model Cerebral System

    • F. L. Margolis, A. Keller, D. Ferriero
    Pages 137-143

  10. Techniques for Separation of Neurons and Glia and Their Application to Metabolic Studies

    • Anders Hamberger, Ã…ke Sellström
    Pages 145-166

  11. Compartmentation of Striatal Dopamine: Problems in Assessing the Dynamics of Functional and Storage Pools of Transmitters

    • E. Costa, A. Carenzi, D. Cheney, A. Guidotti, G. Racagni, B. Zivkovic
    Pages 167-186

  12. Regulation of Synthesis and Release Processes in Central Catecholaminergic Neurons

    • J. Glowinski
    Pages 187-203

  13. Cyclic AMP and Protein Phosphorylation in the Central Nervous System in Relation to Synaptic Function

    • Richard Rodnight
    Pages 205-228

  14. Ortho- and Retrograde Trophic Effects on Adrenergic Neurons: Regulation of Enzyme Synthesis by the Activity of Preganglionic Fibers and Retrograde Axonal Transport of Nerve Growth Factor

    • H. Thoenen, U. Otten, K. Stöckel
    Pages 229-245

  15. Contractile Proteins in Relation to Transmitter Release

    • S. Berl, W. J. Nicklas
    Pages 247-271

  16. Physiology of CNS Tissues in Culture

    • Stanley M. Crain
    Pages 273-303

  17. The Culture of Established Clones for Neurobiologic Investigation

    • Elliott Richelson
    Pages 305-326

  18. Introduction to Simulation Techniques in Neurochemistry

    • David Garfinkel
    Pages 327-336

  19. Metabolic Compartmentation in the Brain and Effects of Metabolic Inhibitors

    • J. H. Quastel
    Pages 337-361

  20. Factors Affecting the Development of Metabolic Compartmentation in the Brain

    • Ambrish J. Patel, Robert Balázs
    Pages 363-383
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Keywords

About this book

The first symposium on metabolic compartmentation in brain was held at the Rockefeller Foundation, Bellagio, Italy, July 11-16, 1971; the proceedings CR. Balazs and J. E. Cremer, editors, MacMillan) appeared in 1973. At the conclusion of the first symposium it was decided to assess in 2-3 years the progress in this rapidly developing area. This volume represents the proceedings of an Advanced Study Institute, made possible by a grant from the North Atlantic Treaty Organization, Scientific Affairs Division. Additional generous support by the Wellcome Trust allowed attendance by participants from non-NATO countries. S. Ber! D. D. Clarke D. Schneider xi Introduction The term metabolic compartmentation, as related to the chemistry of the brain, appeared in print for the first time about 15 years ago. The concept was developed in the laboratory of Dr. Heinrich Waelsch as a result of studies related to the metabolism of glutamic acid and glutamine. It was welcomed by a number of neurochemists who felt that the concept had validity and would help explain metabolic phenomena that were otherwise quite puzzling. The concept gradually achieved general acceptance, and by 1971 the amount of information that could profit by being examined from the point of view of metabolic compartmentation had increased sufficiently to warrant a symposium on the subject ("Metabolic Compartmentation in the Brain," Balazs and Cremer, eds. , MacMillan, 1973). Almost all the participants at that initial symposium were present at the second, on which this volume is based.

Editors and Affiliations

  • Mt. Sinai School of Medicine, New York, USA

    Soll Berl

  • Fordham University, Bronx, USA

    D. D. Clarke

  • Neurosciences Research Program, Boston, USA

    Diana Schneider

Bibliographic Information

  • Book Title: Metabolic Compartmentation and Neurotransmission

  • Book Subtitle: Relation to Brain Structure and Function

  • Editors: Soll Berl, D. D. Clarke, Diana Schneider

  • Series Title: NATO Science Series A:

  • DOI: https://doi.org/10.1007/978-1-4613-4319-6

  • Publisher: Springer New York, NY

  • eBook Packages: Springer Book Archive

  • Copyright Information: Springer Science+Business Media New York 1975

  • Softcover ISBN: 978-1-4613-4321-9Published: 26 November 2012

  • eBook ISBN: 978-1-4613-4319-6Published: 07 March 2013

  • Edition Number: 1

  • Number of Pages: XXIII, 721

  • Topics: Science, Humanities and Social Sciences, multidisciplinary

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