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Kidney in Essential Hypertension

Proceedings of the Course on the Kidney in Essential Hypertension held at New Orleans, Louisiana, March 18–19, 1983

  • Conference proceedings
  • © 1984

Overview

Editors:
  1. Franz H. Messerli

    1. Hemodynamic Laboratory, Ochsner Clinic and Alton Ochsner Medical Foundation, New Orleans, USA
      Tulane University School of Medicine, New Orleans, USA

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Part of the book series: Developments in Cardiovascular Medicine (DICM, volume 35)

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Table of contents (19 papers)

  1. Front Matter

    Pages i-xii
    Download chapter PDF

  2. The Kidney in the Pathogenesis of Essential Hypertension

    1. The Relation of a Circulating Sodium Transport Inhibitor to Essential Hypertension

      • H. E. de Wardener, G. A. MacGregor
      Pages 1-14

    2. Atrial Natriuretic Factor

      • Nick C. Trippodo
      Pages 15-23

    3. The Physiology and Cell Biology of the Renin-Angiotensin System in Hypertension

      • Richard Re
      Pages 25-41

    4. Prostaglandins and Hypertension

      • John C. McGiff
      Pages 43-54

    5. Kallikrein and Kinins in Epithelial Ion Transport

      • Harry S. Margolius, Julie Chao, Alan W. Cuthbert
      Pages 55-64

    6. Renal Afferent Nerves: Evidence for a Role in Cardiovascular Regulation and the Pathogenesis of Experimental Hypertension

      • S. Winternitz, J. M. Wyss, S. Oparil
      Pages 65-75

    7. Renal Blood Flow and Function in Essential Hypertension

      • N. K. Hollenberg
      Pages 77-85

    8. The Kidney and Experimental Hypertension

      • John E. Hall, Arthur C. Guyton, Joey P. Granger, Thomas G. Coleman
      Pages 87-103

  3. The Kidney as a Target Organ in Essential Hypertension

    1. Determinants of Exaggerated Natriuresis in Arterial Hypertension

      • Friedrich C. Luft, M. H. Weinberger
      Pages 105-123

    2. Renal Hemodynamics in Obese and Lean Essential Hypertensive Patients

      • Efrain Reisin, Franz H. Messerli, Hector O. Ventura, Edward D. Frohlich
      Pages 125-129

    3. Sodium and Water Excretion in Patients with Congestive Heart Failure and Cirrhosis

      • Daniel Bichet, R. W. Schrier
      Pages 131-147

    4. Comparison of Renal Hemodynamics in Black and White Patients with Essential Hypertension

      • E. D. Frohlich, F. H. Messerli, F. G. Dunn
      Pages 149-156

  4. Antihypertensive Treatment and the Kidney

    1. Effects of Beta-Adrenergic Antagonists and Diuretics on Kidney Function in Hypertensive Patients

      • J. I. M. Drayer, P. L. Kraut, M. A. Weber
      Pages 157-169

    2. Effects of Central Alpha-Adrenoceptor Agonists and Adrenergic-Neuronal Blocking Agents on the Kidney

      • John H. Bauer
      Pages 171-191

    3. Effects of Alpha1-Adrenoceptor Antagonists and Directly Acting Vasodilators on the Kidney

      • John H. Bauer
      Pages 193-207

    4. Diuretics and the Kidney

      • John H. Dirks
      Pages 209-225

    5. Converting Enzyme Inhibition and the Kidney: Effect on Potassium Homeostasis and Renal Function

      • E. L. Bravo, S. C. Textor, L. Tadena-Thome
      Pages 227-234

    6. Systemic and Renal Hemodynamic Effects of Enalapril in Patients with Essential Hypertension

      • Francis G. Dunn, Wille Oigman, Hector O. Ventura, Franz H. Messerli, Isaac Kobrin, Edward D. Frohlich
      Pages 235-245

    7. Antihypertensive Treatment in Renal Failure

      • Francois C. Reubi
      Pages 247-259
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Keywords

About this book

The kidney, similar to the heart, plays a three-fold role in essential hypertension. First, it participates in the patho­ genesis of arterial hypertension. Second, it suffers as a target organ of long-standing hypertension, and third, it experiences the effects of antihypertensive therapy. Perhaps most contested at the present time is the involvement of the kidney in the patho­ genesis of essential hypertension. More than a century ago, William Osler put forward three basic hypotheses about the "genuine contracted kidney. "l 1. "The hypertrophy can be regarded as an effect to overcome a sort of stop-cock action of the vessels when under the influence of an irritating ingredient in the blood greatly contracted and increased the peripheral resistance. " Clearly this hypothesis of an "irritating ingredient" is perhaps the most convincing nowadays, and numerous attempts have been made to identify a specific vasoconstrictive agent in the blood in essential hypertension. 2. "The obliteration of a large number of capillary territories in the kidney materially raised the arterial pressure. An additional factor of dimin­ ished excretion of water also heightened the pressure within the blood vessel. " Today we know that fluid volume overload in the presence of reduced renal mass seems to be the most likely mechanism accoun­ ting for renal parenchymal hypertension and, as shown by Guyton's group, for certain forms of experimental hypertension. 3.

Editors and Affiliations

  • Hemodynamic Laboratory, Ochsner Clinic and Alton Ochsner Medical Foundation, New Orleans, USA

    Franz H. Messerli

  • Tulane University School of Medicine, New Orleans, USA

    Franz H. Messerli

Bibliographic Information

  • Book Title: Kidney in Essential Hypertension

  • Book Subtitle: Proceedings of the Course on the Kidney in Essential Hypertension held at New Orleans, Louisiana, March 18–19, 1983

  • Editors: Franz H. Messerli

  • Series Title: Developments in Cardiovascular Medicine

  • DOI: https://doi.org/10.1007/978-1-4613-3897-0

  • Publisher: Springer New York, NY

  • eBook Packages: Springer Book Archive

  • Copyright Information: Martinus Nijhoff Publishing, Boston 1984

  • Hardcover ISBN: 978-0-89838-616-5Published: 30 November 1983

  • Softcover ISBN: 978-1-4613-3899-4Published: 14 February 2012

  • eBook ISBN: 978-1-4613-3897-0Published: 06 December 2012

  • Series ISSN: 0166-9842

  • Edition Number: 1

  • Number of Pages: XII, 260

  • Topics: Cardiology, Nephrology

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