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Concepts in Viral Pathogenesis

  • Textbook
  • © 1984

Overview

Editors:
  1. Abner Louis Notkins

    1. National Institutes of Health, Bethesda, USA

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    You can also search for this editor in PubMed   Google Scholar

  2. Michael B. A. Oldstone

    1. Department of Immunopathology, Scripps Clinic and Research Foundation, La Jolla, USA

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    You can also search for this editor in PubMed   Google Scholar

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Table of contents (53 chapters)

  1. Front Matter

    Pages i-xviii
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  2. Host Control of Viral Spread

    1. Front Matter

      Pages 1-2
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    2. Early Non-immune Control

      1. Interferon and Viral Pathogenesis
        • G. John Stanton, S. Baron
        Pages 3-10
      2. Natural Killer Cells in Viral Infection
        • Paolo Casali, Giorgio Trinchieri
        Pages 11-19
      3. The Role of the Complement System in Host Defense Against Virus Diseases
        • Neil R. Cooper
        Pages 20-25
      4. Proteolytic Cleavage and Virus Pathogenesis
        • Andreas Scheid, Purnell W. Choppin
        Pages 26-31

    3. Immune Control—Humoral

      1. Mechanisms of Virus Neutralization
        • Benjamin Mandel
        Pages 32-38
      2. Antibody- and Complement-Dependent Lysis of Virus-Infected Cells
        • J. G. P. Sissons
        Pages 39-45

    4. Immune Control—Cellular

      1. The Inflammatory Response to Acute Viral Infections
        • Diane E. Griffin
        Pages 46-52
      2. MHC Restriction and Cytotoxic T Lymphocytes
        • P. C. Doherty, R. M. Zinkernagel
        Pages 53-57
      3. Antibody-Dependent Cellular Cytotoxicity (ADCC) Mediated by Human Killer Lymphocytes (K-Cells)
        • Peter Perlmann
        Pages 58-64
      4. Cloning of Functional T Lymphocytes
        • Jean-Charles Cerottini, H. Robson MacDonald
        Pages 65-70

    5. Genetic Control

      1. Host Genes that Influence Susceptibility to Viral Diseases
        • Margo A. Brinton, Kenneth J. Blank, Neal Nathanson
        Pages 71-78
      2. Host Genes Controlling the Immune Response
        • Hugh O. McDevitt
        Pages 79-85
      3. On the Role of Recombinant Retroviruses in Murine Leukemia
        • John H. Elder
        Pages 86-93

  3. Host Range and Tissue Tropism

    1. Front Matter

      Pages 95-95
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    2. Viral Receptors: Expression, Regulation and Relationship to Infectivity

      • Patrick R. McClintock, Abner Louis Notkins
      Pages 97-101

    3. Viral Genes and Tissue Tropism

      • Bernard N. Fields
      Pages 102-108

    4. Utilization of Host Proteins as Virus Receptors

      • Gregory H. Tignor, Abigail L. Smith, Robert E. Shope
      Pages 109-116

    5. Host Range and Tissue Tropisms: Antibody-Dependent Mechanisms

      • James S. Porterfield, M. Jane Cardosa
      Pages 117-122
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About this book

The current proliferation of scientific information makes it difficult for even the most diligent reader to keep up with the latest developments in his/her own field, let alone other areas of interest. Review articles are one solution, but they too have become so voluminous and detailed that they often defeat the purpose for which they were intended. We have attempted to ease this problem by using a different format. In this volume on Concepts in Viral Pathogenesis, we have assembled a series of mini-reviews/editorials, 1,000 to 2,000 words in length. Each is a pithy distil­ lation of the state-of-the-art with emphasis on current thinking and unifying concepts rather than a compendium of the literature. The 53 articles, all written by active workers in their respective fields, are organized systemati­ cally so that the book will provide busy investigators, teachers and students of up-to-date information in a very brief and easily read­ a conceptual core able form. In addition, the authors have attempted to identify unresolved problems and point to future directions.

Editors and Affiliations

  • National Institutes of Health, Bethesda, USA

    Abner Louis Notkins

  • Department of Immunopathology, Scripps Clinic and Research Foundation, La Jolla, USA

    Michael B. A. Oldstone

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