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Drugs Affecting Lipid Metabolism VIII

  • Book
  • © 1985

Overview

Editors:
  1. David Kritchevsky

    1. The Wistar Institute of Anatomy and Biology, Philadelphia, USA

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  2. William L. Holmes

    1. West Chester, USA

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  3. Rodolfo Paoletti

    1. Institute of Pharmacology and Pharmacognosy, University of Milan, Milan, Italy

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Part of the book series: Advances in Experimental Medicine and Biology (AEMB, volume 183)

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Table of contents (28 chapters)

  1. Front Matter

    Pages i-xiii
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  2. Cellular Biology of Atherosclerosis

    1. The Cellular Pathobiology of Atherosclerosis In 1983

      • Robert W. Wissler
      Pages 1-16

    2. Secretory Functions of the Mononuclear Phagocyte

      • W. A. Scott, N. A. Pawlowski, E. B. Cramer, Z. A. Cohn
      Pages 17-25

    3. Risk Factors for the Development of Premature Cardiovascular Disease

      • H. Bryan Brewer Jr., Dennis L. Sprecher, Richard E. Gregg, Jeffrey M. Hoeg
      Pages 27-36

    4. Fate of Cholesteryl Linoleyl Ether Injected Into Rats as Chylomicrons, Acetylated LDL and HDL

      • Yechezkiel Stein, Olga Stein
      Pages 37-46

    5. Hypertriglyceridemia: Lipoprotein Receptors and Atherosclerosis

      • S. H. Gianturco, A. M. Gotto Jr., W. A. Bradley
      Pages 47-71

    6. Hypertriglyceridemia and Atherosclerosis Analysis of an Abnormal Lipoprotein System and Potential Beneficial Effects of Triglyceride Lowering Therapy

      • Shlomo Eisenberg
      Pages 73-84

  3. Apolipoprotein

    1. The Role of Hydrophobicity in the Structure of the Human Plasma Lipoproteins

      • Henry J. Pownall, Antonio M. Gotto Jr.
      Pages 85-97

    2. Metabolism of Apolipoproteins and the Metabolic Heterogeneity of Apo B in the Rat

      • Julian B. Marsh
      Pages 99-112

    3. Proapolipoprotein A-I Metabolism in the Human and the Rat

      • Giancarlo Ghiselli, Bette C. Sherrill
      Pages 113-120

    4. Isolation and Characterization of the Apolipoprotein Genes

      • Jan L. Breslow
      Pages 121-124

    5. Apoprotein Measurements

      • John J. Albers
      Pages 125-133

    6. Use of Monoclonal Antibodies in Studies of Lipoprotein Structure and Function

      • Gustav Schonfeld, Matti J. Tikkanen, Kyung-soo Hahm
      Pages 135-157

    7. Apolipoprotein E: Receptor Binding Properties

      • K. H. Weisgraber, T. L. Innerarity, S. C. Rall Jr., R. W. Mahley
      Pages 159-171

    8. Apolipoprotein E Mutants, Hyperlipidemia and Arteriosclerosis

      • Gerd Utermann
      Pages 173-188

  4. Noninvasive Assessment of Atherosclerosis

    1. Noninvasive Assessment of Atherosclerosis in Nonhuman Primates

      • M. Gene Bond, Sharon K. Wilmoth, Jean F. Gardin, Ralph W. Barnes, Janet K. Sawyer
      Pages 189-195

    2. Noninvasive Assessment of Atherosclerosis: Studies in Man

      • Robert J. Lusby
      Pages 197-208

    3. Noninvasive Atherosclerosis Assessment for Controlled Clinical Trials

      • David H. Blankenhorn
      Pages 209-223
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Keywords

About this book

The Proceedings of the Eight International Symposium on Drugs Affecting Lipid Metabolism (8th D.A.L.M.) is the subject of this volume. Since the first symposium in 1960, each successive meeting has broken new ground in the field of pharmacological control of lipid levels - offering new and stimulating insights and exposing the audience to the state of the art. The field has progressed sufficiently to permit discussion of the cellular biology of athero­ sclerosis. The opening session was devoted to pathology, macrophages, lipoproteins and their receptors and choles­ terol ester metabolism. Because of the recent emergence of new apolipoprotein technology, a workshop devoted sole­ ly to apolipoprotein methodology was introduced followed by a plenary session devoted to their metabolism and structure. Another rapidly developing area of atherosclerosis research is non-invasive assessment of this condition. Accordingly, a session was devoted to new techniques for this research modality. The final plenary sessions were devoted to the roles of drugs and diet in athero~ scl~rosis - cause, treatment and mechanisms of action. The meeting was summarized by Dr. O.J. Pollak, one of the "founding fathers" of this field. There were nine sessions of proffered papers whose abstracts appear in this volume. In addition, special workshops (to be reported elsewhere) were devoted to several drugs including Oiyzanol, Probucol and Etofibrate.

Editors and Affiliations

  • The Wistar Institute of Anatomy and Biology, Philadelphia, USA

    David Kritchevsky

  • West Chester, USA

    William L. Holmes

  • Institute of Pharmacology and Pharmacognosy, University of Milan, Milan, Italy

    Rodolfo Paoletti

Bibliographic Information

  • Book Title: Drugs Affecting Lipid Metabolism VIII

  • Editors: David Kritchevsky, William L. Holmes, Rodolfo Paoletti

  • Series Title: Advances in Experimental Medicine and Biology

  • DOI: https://doi.org/10.1007/978-1-4613-2459-1

  • Publisher: Springer New York, NY

  • eBook Packages: Springer Book Archive

  • Copyright Information: The Editor(s) (if applicable) and The Author(s), under exclusive license to Springer Science+Business Media, LLC, part of Springer Nature 1985

  • Softcover ISBN: 978-1-4612-9493-1Published: 12 December 2012

  • eBook ISBN: 978-1-4613-2459-1Published: 06 December 2012

  • Series ISSN: 0065-2598

  • Series E-ISSN: 2214-8019

  • Edition Number: 1

  • Number of Pages: XIV, 502

  • Number of Illustrations: 74 b/w illustrations

  • Topics: Pharmacology/Toxicology

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