Overview
- Editors:
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Andor Szentivanyi
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Department of Pharmacology and Therapeutics, Unversity of South Florida, Tampa, USA
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Paul H. Maurer
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Department of Biochemistry, Jefferson Medical College of Thomas Jefferson University, Philadelphia, USA
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Bernard W. Janicki
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Immunology, Allergic and Immunologic Diseases Program National Institute of Allergy and Infectious Disease, National Institutes of Health, Bethesda, USA
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Table of contents (17 chapters)
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Front Matter
Pages i-viii
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Structures of Antibodies and the Combining Site
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- Keith J. Dorrington, Michel H. Klein
Pages 3-10
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- Heinz Kohler, Thomas Kieber-Emmons
Pages 11-17
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B Cell Development, Function, Repertoire and Activation
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- Nicolas Fasel, Michael Briskin, Carla Carter, Herman Govan, Gary Hermanson, Ronald Law et al.
Pages 49-60
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- Barbara G. Froscher, Norman R. Klinman
Pages 61-69
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- Junichiro Mizuguchi, Michael Beaven, Peter Hornbeck, Wayne Tsang, William E. Paul
Pages 71-78
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Antiboby Idiotypes, Anti-Idiotypes, and Network Regulation
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- Michael F. Gurish, Tamar Ben-Porat, Alfred Nisonoff
Pages 81-89
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- Carol Victor-Kobrin, Zahava Barak, F. A. Bonilla, Constantin Bona
Pages 91-105
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- Gregory W. Siskind, Edmond A. Goidl, Young Tai Kim, Marc E. Weksler, G. Jeanette Thorbecke
Pages 107-115
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Immunologic Intervention with Anti-Idiotype Antibodies
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Front Matter
Pages 117-117
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- B. F. Erlanger, W. L. Cleveland, N. H. Wasserman, H. H. Ku, B. L. Hill, R. Sarangarajan et al.
Pages 119-134
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Immunologic Intervention with Monoclonal Antibodies
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Front Matter
Pages 165-165
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- Sherie L. Morrison, Letitia A. Wims, Polly D. Gregor, Barry J. Kobrin, Vernon T. Oi
Pages 167-178
About this book
This publication is based on a Symposium that has been held in Clearwater, Florida on February 19-21, 1986, on antibodies, their structure, synthesis, function, and clinical applicability in disease. Organization of this symposium by the University of South Florida College of Medicine was prompted by the unparalleled current expansion of information on these topics in general, and in the field of antibody diver sity, in particular. The issues that surround the last named dimension of this field, began to surface in the late 1950's with the first conclusive genetic studies having been answered, and a new set of concepts has been de fined. As we see it from the material presented in this volume, now new and different questions are being raised and answered by studies in progress, and it may be expected that there will be other questions that will be with us for a considerably longer time. We believe that the symposium brought together many prominent investi gators with different backgrounds and training experiences such as immunolo gists, microbiologists, biochemists, molecular biologists, and clinical sci entists, thus providing an excellent example of the interdisciplinary value of modern immunology and modern biomedical science in general. We believe, therefore, that bringing these complex topics to a wide audience of bio medical scientists through this symposium as well as this volume is of value to the scientific and to the medical community.
Editors and Affiliations
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Department of Pharmacology and Therapeutics, Unversity of South Florida, Tampa, USA
Andor Szentivanyi
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Department of Biochemistry, Jefferson Medical College of Thomas Jefferson University, Philadelphia, USA
Paul H. Maurer
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Immunology, Allergic and Immunologic Diseases Program National Institute of Allergy and Infectious Disease, National Institutes of Health, Bethesda, USA
Bernard W. Janicki
