Skip to main content
SpringerLink
Log in

The Serotonin Receptors

  • Book
  • © 1988

Overview

Editors:
  1. Elaine Sanders-Bush

    1. Department of Pharmacology and Psychiatry, Vanderbilt University School of Medicine, Nashville, USA

    View editor publications

    You can also search for this editor in PubMed   Google Scholar

Part of the book series: The Receptors (REC)

This is a preview of subscription content, log in via an institution to check access.

Access this book

Log in via an institution
eBook USD 84.99
Price excludes VAT (USA)
  • Available as PDF
  • Read on any device
  • Instant download
  • Own it forever
Softcover Book USD 109.99
Price excludes VAT (USA)
  • Compact, lightweight edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info
Hardcover Book USD 109.99
Price excludes VAT (USA)
  • Durable hardcover edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info

Tax calculation will be finalised at checkout

Other ways to access

Licence this eBook for your library

Institutional subscriptions

Table of contents (12 chapters)

  1. Front Matter

    Pages i-xvi
    Download chapter PDF

  2. Historical Perspectives

    1. Front Matter

      Pages 1-1
      Download chapter PDF

    2. Historical Perspectives

      • Samuel S. Wang, Stephen J. Peroutka
      Pages 3-20

  3. Characterization of Serotonin Receptor Binding Sites

    1. Front Matter

      Pages 21-21
      Download chapter PDF

    2. Biochemistry and Pharmacology of the 5-HT1 Serotonin Binding Sites

      • David L. Nelson
      Pages 23-57

    3. Pharmacology and Biochemistry of the 5-HT2 Receptor

      • Robert A. Lyon, Milt Titeler
      Pages 59-88

    4. Autoradiographic Studies of Serotonin Receptors

      • J. M. Palacios, M. M. Dietl
      Pages 89-138

  4. Biochemical Mechanisms of Receptor Action

    1. Front Matter

      Pages 139-139
      Download chapter PDF

    2. 5-HT Receptors Coupled to Adenylate Cyclase

      • Michael De Vivo, Saul Maayani
      Pages 141-179

    3. 5-HT Receptors Coupled to Phosphoinositide Hydrolysis

      • Elaine Sanders-Bush
      Pages 181-198

  5. Correlation of Binding Sites with Function

    1. Front Matter

      Pages 199-199
      Download chapter PDF

    2. Autoreceptors Regulating Serotonin Release

      • Derek N. Middlemiss
      Pages 201-224

    3. Electrophysiology of Central Serotonin Receptor Subtypes

      • G. K. Aghajanian, J. S. Sprouse, K. Rasmussen
      Pages 225-252

    4. Behavioral Models of Serotonin Receptor Activation

      • Richard A. Glennon, Irwin Lucki
      Pages 253-293

    5. Serotonin Receptors in Vascular Smooth Muscle

      • Marlene L. Cohen
      Pages 295-316

  6. Regulation of Serotonin Receptors

    1. Front Matter

      Pages 317-317
      Download chapter PDF

    2. Regulation of Serotonin Receptors and Responsiveness in the Brain

      • Alan Frazer, Steve J. Offord, Irwin Lucki
      Pages 319-362

  7. Future Vistas

    1. Front Matter

      Pages 363-363
      Download chapter PDF

    2. Future Vistas

      • Elaine Sanders-Bush
      Pages 365-366

  8. Back Matter

    Pages 367-388
    Download chapter PDF
Back to top

Keywords

About this book

Serotonin (5-HT) was isolated and chemically characterized nearly four decades ago, and is now generally accepted to function as a neurotransmitter and neuromodulatory agent. Early research focused on the measurement of concentrations, synthesis, and metabolism of 5-HT, and only recently has the focus shifted to characterization of 5-HT receptors. Gaddum and Picarelli first sug­ gested in 1957 that the effect of 5-HT in the guinea pig ileum is mediated by two pharmacologically distinguishable receptors; however, the possibility of dual5-HT receptors was not explored systematically or successfully until the past decade. It is now clear that more, perhaps many more, subclasses of 5-HT receptors exist. The purpose of this book is to provide an up-to-date report on 5-HT receptors. This is a difficult task considering the astonishing speed at which research in this field is expanding. As the first of what we can expect to be a steady stream of monographs focusing on 5-HT receptors, the book confirms that we are in an exciting time in the history of 5-HT. For those of us who have been work­ ing on 5-HT for many years, our dream of equal progress and recognition with the more extensively studied catecholamines is finally being realized. We now have a Serotonin Club that held its first international scientific meeting in 1987, and several more international meetings are in the planning stages.

Editors and Affiliations

  • Department of Pharmacology and Psychiatry, Vanderbilt University School of Medicine, Nashville, USA

    Elaine Sanders-Bush

Bibliographic Information

  • Book Title: The Serotonin Receptors

  • Editors: Elaine Sanders-Bush

  • Series Title: The Receptors

  • DOI: https://doi.org/10.1007/978-1-4612-4560-5

  • Publisher: Humana Totowa, NJ

  • eBook Packages: Springer Book Archive

  • Copyright Information: The Humana Press Inc. 1988

  • Hardcover ISBN: 978-0-89603-142-5Published: 03 February 1989

  • Softcover ISBN: 978-1-4612-8912-8Published: 05 October 2011

  • eBook ISBN: 978-1-4612-4560-5Published: 06 December 2012

  • Series ISSN: 1048-6909

  • Series E-ISSN: 2524-6488

  • Edition Number: 1

  • Number of Pages: XVI, 388

  • Topics: Neurosciences

Publish with us

Policies and ethics

Back to top

Search

Navigation