Overview
- Editors:
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Earl A. Surwit
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Southern Arizona Surgical Oncology, Ltd, Tucson, USA
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David S. Alberts
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College of Medicine, University of Arizona, Tucson, USA
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Table of contents (9 chapters)
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- Lynda F. Voigt, Noel S. Weiss
Pages 1-21
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- Gerard Wain, C. Paul Morrow
Pages 23-40
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- P. G. Satyaswaroop, R. J. Zaino, R. Mortel
Pages 71-92
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- Charles E. Welander, Charles M. Jones III, David S. Alberts, Sydney E. Salmon
Pages 117-126
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Back Matter
Pages 127-131
About this book
The incidence of endometrial cancer rose sharply in the United States in the early 1970s, paralleling changes in the use of postmenopausal estrogens by American women. A sizeable body of evidence supports the role of both excessive endogenous estrogen and exogenous estrogen in the etiology of endometrial cancer. There is growing evidence that inadequate progesterone has the opposite effect, in that progesterone supplementation of postmeno pausal estrogen therapy reduces the incidence of endometrial cancer. Despite this new awareness of the hormonal role that is played in carcino ma of the endometrium, the disease still plagues the oncologist. The general approach to carcinoma of the endometrium in the United States is that of primary surgical staging. This provides the maximum amount of information to best plan postoperative radiation therapy and/or chemotherapy for these patients. In general, patients who are considered candidates for surgical staging are those with advanced disease or high-risk stage I endometrial carcinoma. High-risk endometrial carcinoma is defined as those patients with moderately differentiated lesions with deep myometrial invasion, poor ly differentiated carcinoma of the endometrium, and the high-risk histolo gies such as papillary carcinoma and clear-cell carcinomas. The surgical staging has extended in most institutions to patients with occult stage II carcinoma of the endometrium, i. e.
Reviews
`I recommend this book to physicians, especially gynaecologic and medical oncologists who would like to have a comprehensive summary of new aspects in the management of endometrial cancer.'
M. Kaufmann, Annals of Oncology, 1990
Editors and Affiliations
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Southern Arizona Surgical Oncology, Ltd, Tucson, USA
Earl A. Surwit
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College of Medicine, University of Arizona, Tucson, USA
David S. Alberts