Advances in Assisted Reproductive Technologies

1. Front Matter

   Pages i-xvii

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2. Controversies in Induction of Ovulation

   1. Is There a Best Stimulation Protocol?

      • Howard W. Jones Jr., Georgeanna S. Jones, Suheil J. Muasher, Debbie Jones

      Pages 1-15

   2. Limitations in the Use of Combined Gonadotropin Releasing Hormone Analog and Human Menopausal Gonadotropin for In Vitro Fertilization

      • Z. Ben-Rafael, Y. Menashe, R. Mimon, S. Lipitz, D. Bider, M. Zolti et al.

      Pages 17-29

   3. The Combined Pituitary Suppression/Ovarian Stimulation Therapy: Myths and Realities

      • V. Insler, E. Lunenfeld, G. Potashnik, J. Levy

      Pages 31-38

   4. Past Present and Future of Gonadotropins

      • Bruno Lunenfeld

      Pages 39-45

3. Aspects of Ovarian Stimulation in Medically Assisted Reproduction

   1. Physiology of Follicle Development in Stimulated Cycles

      • Torbjörn Hillensjö, Jan-Henrik Olsson, Lars Hamberger

      Pages 47-52

   2. Safe Gonadotrophins

      • H. M. Vemer, E. H. Houwink

      Pages 53-54

   3. IVF: LH Surge vs hCG

      • Douglas Keeping

      Pages 55-63

   4. Experience with GnRH-Agonists in Ovarian Stimulation

      • K. Diedrich, R. Schmutzler, Ch. Diedrich, H. van der Ven, S. Al-Hasani, D. Krebs

      Pages 65-75

   5. The Association of Ovarian Hyperstimulation and Zygote Intrafallopian Transfer

      • P. Devroey, C. Staessen, M. Camus, A. Wisanto, N. Bollen, P. Henderix et al.

      Pages 77-82

4. Ovarian Physiology

   1. Control of follicular growth During the primate menstrual cycle

      • Anthony J. Zeleznik

      Pages 83-91

   2. Growth Factor Modulation of Gonadotropin Action on Porcine Granulosa Cells

      • Takahide Mori, Kenji Takakura, Masatsune Fukuoka, Shunzo Taii, Keiko Yasuda

      Pages 93-101

   3. Follicular Rupture During Ovulation: Activation of Collagenolysis

      • A. Tsafriri, D. Daphna-Iken, A. O. Abisogun, R. Reich

      Pages 103-112

   4. Involvement of Calcium in the Transduction of the Hormonal Signal for Induction of Oocyte Maturation

      • Nava Dekel, Sari Goren, Yoram Oron

      Pages 113-118

   5. Hydration as the Key Event in Mucificatton of the Rat Cumulus

      • Y. Barak, P. F. Kraicer, M. Kostiner, Z. Nevo

      Pages 119-127

   6. Tumor Necrosis Factor (TNFα) and the Endogenous Prostaglandin Inhibitor (PGIn) in Bovine Follicles

      • M. Shemesh, R. Meiron, M. Zolti, Z. Ben-Rafael, D. R. Wollach

      Pages 129-137

   7. The Role of Tumor Necrosis Factor in Human Granulosa Cells and Early Embryo

      • M. Zolti, R. Meirom, M. Shemesh, D. Wallach, S. Mashiach, Z. Ben-Rafael

      Pages 139-146

   8. The Ovarian Renin-Angiotensin System and Compartmental Function in the Ovary

      • R. Apa, T. Zreik, A. Lightman, A. Palumbo, T-K. Yoon, P. Andrade-Gordon et al.

      Pages 147-151

   9. The Physiology of Human Ovarian Prorenin-Angiotensin System

      • Joseph Itskovitz, Jean E. Sealey

      Pages 153-168

5. GnRH and GnRH Analogs: Basic Aspects

   1. Prolactin as a Possible Modulator of Gonadotropin Action on the Ovary

      • Yitzhak Koch, Nava Dekel

      Pages 169-174

The World Congress of In Vitro Fertilization and Alternate Assisted Reproduction, held in Jerusalem, Israel, 2-7 April, 1989, was the sixth in the sequence of these Congresses, but was the first to emphasize the major importance and the place of assisted reproductive technologies in the treatment of infertility. The eternal City of Jerusalem witnessed the gathering of more than 1500 participants from allover the world who shared and exchanged knowledge and up-to-date experience in this ever-evolving field. The high quality scientific contributions to the Congress culminated in the publication of this Proceedings. It embraces all-important aspects in the field of in vitro fertilization and alternate assisted reproduction. Papers on controversies and diversities of methods to stimulate the ovaries, imaging techniques, basic research and state-of-the-art papers on ovarian physiology, the role of GnRH and its analog, clinical aspects of IVF treatment and cryopreservation, up-to-date techniques in assisted reproductive technologies that are quickly developing in conjunction with IVF, were included. When should IVF be preferable to surgery? What are the ex­ pected up-to-date world results and what are the psychological, moral, ethical and religious implications? These are all the concerns of the treating team and are addressed here. Male factor infertility remains a frustrating problem, but advances in the understanding of sperm-egg interaction, sperm evaluation and preparation are reported. Micromanipulation emerges as a possible alternative to bring some relief to this problem, but it also promises to be central in promoting the field of prenatal genetic analysis.

• Calcium
• Hydra
• ethics
• infertility
• physiology
• ultrasound

Policies and ethics