Brain Ischemia

1. Front Matter

   Pages i-xiii

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2. The Brain

   1. Front Matter

      Pages 1-1

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   2. Prefatory Comments

      • Louis R. Caplan

      Pages 3-6

   3. Mechanisms of Cell Death in Ischemia

      • J. H. Garcia

      Pages 7-18

   4. Positron Emission Tomography (PET) in Acute Ischemic Stroke: Pathophysiological and Clinical Implications

      • J. C. Baron

      Pages 19-27

   5. Excitotoxicity and Stroke

      • D. W. Choi

      Pages 29-36

   6. Growth Factors in Stroke

      • S. P. Finklestein

      Pages 37-41

   7. Ischemic Cerebral Edema

      • M. D. O’Brien

      Pages 43-50

   8. Concluding Comments

      • Louis R. Caplan

      Pages 51-56

3. The Eye

   1. Front Matter

      Pages 57-57

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   2. Prefatory Comments

      • Louis R. Caplan

      Pages 59-60

   3. Ocular Ischemia

      • T. R. Hedges

      Pages 61-73

   4. Concluding Comments

      • Louis R. Caplan

      Pages 75-79

4. The Blood

   1. Front Matter

      Pages 81-81

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   2. Prefatory Comments

      • Louis R. Caplan

      Pages 83-84

   3. Coagulation

      • W. M. Feinberg

      Pages 85-96

   4. Immunohematologic Mechanisms in Stroke

      • M. J. Fisher

      Pages 97-103

   5. Fibrinolysis and its Relevance to Acute Focal Cerebral Ischemia

      • G. J. del Zoppo

      Pages 105-119

   6. Concluding Comments

      • Louis R. Caplan

      Pages 121-126

5. The Blood Vessels

   1. Front Matter

      Pages 127-127

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Professor Caplan has extensively edited the book to shape and organize the contents into a succinct presentation by experts of the basic science and clinical aspects of the topic. The text has been divided into sections: The Brain.- Macroscopic and microscopic molecular aspects of brain ischemia, including pathophysiology, pathology, biochemistry, and clinical measurement.- Blood Vessels.- Their constitution and the pathology and physiology of the endothelium and arterial wall.- Blood Flow.- Its physics, control, rheology, and pathophysiology.- Blood.- The role of the cellular and serological constituents in coagulation and fibrinolysis. - Heart.- Sources of embolism and cardiac changes caused by brain ischemia.- And Epidemiology, Databases, and Trials. Prefatory remarks by Professor Caplan introduce each section. At the end of each section he relates the basic concepts to patient problems in the clinic, integrates the various contributions in the section, and covers other areas not discussed by the individual contributors.

• PET
• biochemistry
• brain
• cerebral ischemia
• intracranial pressure
• neuroprotection
• pathophysiology
• physiology
• positron emission tomography (PET)
• stroke
• tomography

• Department of Neurology, New England Medical Center Hospitals, Boston, USA

  Louis R. Caplan

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