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The Embryo

Normal and Abnormal Development and Growth

  • Book
  • © 1991

Overview

Editors:
  1. Michael G. Chapman

    1. Department of Obstetrics and Gynaecology, Guy’s Hospital, London, UK

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  2. J. Gedis Grudzinskas

    1. Academic Unit of Obstetrics and Gynaecology, The London Hospital, Whitechapel, London, UK

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  3. Tim Chard

    1. Academic Unit of Reproductive Physiology, St Bartholomew’s Hospital Medical College, London, UK

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Table of contents (17 chapters)

  1. Front Matter

    Pages i-xi
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  2. Mechanisms of Early Embryonic Loss In Vivo and In Vitro

    • P. Braude, M. Johnson, S. Pickering, C. Vincent
    Pages 1-10

  3. Aetiology of Pregnancy Failure

    • J. L. Simpson
    Pages 11-34

  4. Anembryonic Pregnancy

    • I. Stabile
    Pages 35-43

  5. Embryonic Loss: Clinical Perspectives

    • J. L. Yovich
    Pages 45-62

  6. Embryo Biopsy

    • V. N. Bolton
    Pages 63-79

  7. Preimplantation Diagnosis by DNA Amplification

    • A. H. Handyside
    Pages 81-90

  8. Transabdominal Chorion Villus Biopsy Versus Amniocentesis for Diagnosis of Aneuploidy: Safety Is Not Enough

    • R. J. Lilford, H. Irving, J. K. Gupta, P. O’Donovan, G. Linton
    Pages 91-100

  9. The Role of Echography in the Diagnosis of Fetal Chromosomal Defects

    • K. H. Nicolaides, R. J. M. Snijders, C. M. Gosden
    Pages 101-121

  10. Embryoscopy: An Evolving Technology for Early Prenatal Diagnosis

    • E. A. Reece, J. C. Hobbins
    Pages 123-140

  11. Sexing the Pre-embryo

    • J. D. West
    Pages 141-164

  12. Embryonic Development: The Origin of Neural Tube Defects

    • A. J. Copp
    Pages 165-180

  13. Ultrasound and Biochemical Assessment of First Trimester Pregnancy

    • B. Brambati, A. Lanzani, L. Tului
    Pages 181-194

  14. Endocrinology and Metabolism in Early Pregnancy

    • J. G. Grudzinskas, T. Chard
    Pages 195-207

  15. The Endocrinology of the Fetoplacental Unit in the Second Trimester of Pregnancy

    • T. Chard, J. G. Grudzinskas
    Pages 209-226

  16. Endometrial Proteins

    • R. Koistinen, M. Julkunen, L. Riittinen, A. M. Suikkari, M. Seppälä
    Pages 227-239

  17. Maternal Serum AFP Screening for Fetal Malformations and Down’s Syndrome

    • B. Nørgaard-Pedersen
    Pages 241-249

  18. Biochemical Screening for Down’s Syndrome

    • N. Wald, H. Cuckle
    Pages 251-257

  19. Back Matter

    Pages 259-263
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Keywords

About this book

A variety of new techniques that promise to revolutionize the clinical management of early pregnancy are fully detailed in this state-of-the-art book. Leading international researchers describe fast-moving topics such as embryo manipulation and the diagnosis of congenital abnormalities. The technology of assisted reproduction has made it possible to study living embryonic material for the first time, which has led to rapid advances in our understanding of the human embryo's early development. For example, study of the embryo in the test tube has pointed to early pregnancy loss as a possible cause of later infertility. Even more important, diagnostic tests using sophisticated techniques of molecular biology can be run on single cells before the embryo is replaced in the uterus. Another area of advance is the diagnosis of congenital abnormalities in the first and second trimesters of pregnancy. Great improvements have been made in the techniques of chorion villus biopsy and ultrasound imaging. A spectrum of simple biochemical tests performed on the mother's blood can greatly improve the detection of Down syndrome and other chromosome defects. Together with other developments in the fields of molecular biology and endocrinology, these new diagnostic techniques are the beginning of a new age in clinical human genetics and embryology.

Editors and Affiliations

  • Department of Obstetrics and Gynaecology, Guy’s Hospital, London, UK

    Michael G. Chapman

  • Academic Unit of Obstetrics and Gynaecology, The London Hospital, Whitechapel, London, UK

    J. Gedis Grudzinskas

  • Academic Unit of Reproductive Physiology, St Bartholomew’s Hospital Medical College, London, UK

    Tim Chard

Bibliographic Information

  • Book Title: The Embryo

  • Book Subtitle: Normal and Abnormal Development and Growth

  • Editors: Michael G. Chapman, J. Gedis Grudzinskas, Tim Chard

  • DOI: https://doi.org/10.1007/978-1-4471-1802-2

  • Publisher: Springer London

  • eBook Packages: Springer Book Archive

  • Copyright Information: Springer-Verlag London Limited 1991

  • Softcover ISBN: 978-1-4471-1804-6Published: 22 November 2011

  • eBook ISBN: 978-1-4471-1802-2Published: 06 December 2012

  • Edition Number: 1

  • Number of Pages: XI, 263

  • Topics: Obstetrics/Perinatology/Midwifery, Endocrinology, Human Genetics, Pediatrics

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