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Cysteine Proteases of Pathogenic Organisms

  • Book
  • © 2011

Overview

Editors:
  1. Mark W. Robinson

    1. Infection, Immunity and Innovation (i3) Institute, University of Technology Sydney, Ultimo, Sydney, Australia

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  2. John P. Dalton

    1. Institute of Parasitology, McGill University, St. Anne de Bellevue, Canada

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    You can also search for this editor in PubMed   Google Scholar

  • Written by leading researchers from Europe, Australia and North America
  • Review recent developments in bacterial cysteine proteases Focuses on protozoan parasites of medical importance
  • Covers cysteine proteases from helminths of medical and veterinary importance

Part of the book series: Advances in Experimental Medicine and Biology (AEMB, volume 712)

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Table of contents (13 chapters)

  1. Front Matter

    Pages i-xix
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  2. Papain-Like Proteases of Staphylococcus aureus

    • Tomasz Kantyka, Lindsey N. Shaw, Jan Potempa
    Pages 1-14

  3. The Lysine-Specific Gingipain of Porphyromonas gingivalis

    • Tang Yongqing, Jan Potempa, Robert N. Pike, Lakshmi C. Wijeyewickrema
    Pages 15-29

  4. Falcipains and Other Cysteine Proteases of Malaria Parasites

    • Philip J. Rosenthal
    Pages 30-48

  5. Cathepsin Proteases in Toxoplasma gondii

    • Zhicheng Dou, Vern B. Carruthers
    Pages 49-61

  6. Entamoeba histolytica Cathepsin-Like Enzymes

    • Vanessa Kissoon-Singh, Leanne Mortimer, Kris Chadee
    Pages 62-83

  7. Cysteine Peptidases of Kinetoplastid Parasites

    • Conor R. Caffrey, Ana-Paula Lima, Dietmar Steverding
    Pages 84-99

  8. Cruzain

    • Mohammed Sajid, Stephanie A. Robertson, Linda S. Brinen, James H. McKerrow
    Pages 100-115

  9. The Phylogeny, Structure and Function of Trematode Cysteine Proteases, with Particular Emphasis on the Fasciola hepatica Cathepsin L Family

    • Colin Stack, John P. Dalton, Mark W. Robinson
    Pages 116-135

  10. Cathepsins B1 and B2 of Trichobilharzia SPP., Bird Schistosomes Causing Cercarial Dermatitis

    • Martin Kašný, Libor Mikeš, Kateřina Dolečková, Vladimír Hampl, Jan Dvořák, Marian Novotný et al.
    Pages 136-154

  11. Proteases in Blood-Feeding Nematodes and Their Potential as Vaccine Candidates

    • David Knox
    Pages 155-176

  12. Cysteine Proteases from Bloodfeeding Arthropod Ectoparasites

    • Daniel Sojka, Ivo M. B. Francischetti, Eric Calvo, Michalis Kotsyfakis
    Pages 177-191

  13. How Pathogen-Derived Cysteine Proteases Modulate Host Immune Responses

    • Sheila Donnelly, John P. Dalton, Mark W. Robinson
    Pages 192-207

  14. Cystatins of Parasitic Organisms

    • Christian Klotz, Thomas Ziegler, Emilia Daniłowicz-Luebert, Susanne Hartmann
    Pages 208-221

  15. Back Matter

    Pages 223-226
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Keywords

About this book

Cysteine proteases expressed by pathogenic organisms play key roles in virulence including host entry, feeding and suppression of host immune responses. This book gives comprehensive coverage to all aspects of pathogen cysteine proteases and brings together numerous scientific advances which have been made over many years. Thus, the biochemistry, molecular biology and structure‑function relationships of these important pathogen enzymes are covered in detail. Written by leading researchers from Europe, Australia and North America, this book is essential reading for students and professionals interested in human medicine and infectious disease research.

Editors and Affiliations

  • Infection, Immunity and Innovation (i3) Institute, University of Technology Sydney, Ultimo, Sydney, Australia

    Mark W. Robinson

  • Institute of Parasitology, McGill University, St. Anne de Bellevue, Canada

    John P. Dalton

About the editors

MARK W. ROBINSON is a Chancellor’s Postdoctoral Research Fellow at the Infection, Immunity and Innovation (i3) Institute at the University of Technology, Sydney (UTS), Australia. Robinson received a BSc (Hons) in Zoology (1999) and a PhD in molecular parasitology (2003) from Queen’s University, Belfast (Northern Ireland). As a postdoctoral researcher, he worked on nematode proteomics and molecular biology at the University of Aberdeen (Scotland) until 2007 when he was awarded a prestigious Wain International Fellowship from the British Biotechnology and Biological Sciences Research Council (BBSRC) to continue his proteomics research at UTS (Australia). Robinson was awarded a UTS Chancellor’s Postdoctoral Fellowship in 2008 which he currently holds as an independent researcher. His research interests include proteomics of host‑pathogen interactions, structure‑function relationships of parasite immuno‑modulators and the molecular biology of helminth proteases.

Bibliographic Information

  • Book Title: Cysteine Proteases of Pathogenic Organisms

  • Editors: Mark W. Robinson, John P. Dalton

  • Series Title: Advances in Experimental Medicine and Biology

  • DOI: https://doi.org/10.1007/978-1-4419-8414-2

  • Publisher: Springer New York, NY

  • eBook Packages: Biomedical and Life Sciences, Biomedical and Life Sciences (R0)

  • Copyright Information: The Editor(s) (if applicable) and The Author(s), under exclusive license to Springer Science+Business Media, LLC, part of Springer Nature 2011

  • Hardcover ISBN: 978-1-4419-8413-5Published: 23 March 2011

  • Softcover ISBN: 978-1-4899-7942-1Published: 23 August 2016

  • eBook ISBN: 978-1-4419-8414-2Published: 10 June 2011

  • Series ISSN: 0065-2598

  • Series E-ISSN: 2214-8019

  • Edition Number: 1

  • Number of Pages: XIX, 226

  • Topics: Biomedicine general, Molecular Medicine

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