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Understanding the Dynamics of Biological Systems

Lessons Learned from Integrative Systems Biology

  • Book
  • © 2011

Overview

Editors:
  1. Werner Dubitzky

    1. Nano Systems Biology Research Group, Biomedical Sciences Research Institute, University of Ulster, Coleraine, United Kingdom

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  2. Jennifer Southgate

    1. Jack Birch Unit of Molecular Carcinogene, Department of Biology, University of York, York, United Kingdom

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  3. Hendrik Fuß

    1. Biomedical Sciences Research Institute, Biomedical Sciences Research Institute, University of Ulster, Coleraine, United Kingdom

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  • This book is for professionals that consider adopting a systems biology approach

  • This book addresses the requirements of scientists and re-searchers to gain an overview and a basic understanding of key systems biology methodologies and tools

  • The contributors have attempted to cover a representative range of life science areas and systems biology methodologies

  • Includes supplementary material: sn.pub/extras

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Table of contents (10 chapters)

  1. Front Matter

    Pages i-xiv
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  2. Effects of Protein Quality Control Machinery on Protein Homeostasis

    • Conner I. Sandefur, Santiago Schnell
    Pages 1-17

  3. Metabolic Network Dynamics: Properties and Principles

    • Neema Jamshidi, Bernhard Ø. Palsson
    Pages 19-37

  4. A Deterministic, Mathematical Model for Hormonal Control of the Menstrual Cycle

    • R. Drew Pasteur, James F. Selgrade
    Pages 39-58

  5. Modeling Transport Processes and Their Implications for Chemical Disposition and Action

    • Nick Plant
    Pages 59-82

  6. Systems Biology of Tuberculosis: Insights for Drug Discovery

    • Karthik Raman, Nagasuma Chandra
    Pages 83-110

  7. Qualitative Analysis of Genetic Regulatory Networks in Bacteria

    • Valentina Baldazzi, Pedro T. Monteiro, Michel Page, Delphine Ropers, Johannes Geiselmann, Hidde de Jong
    Pages 111-130

  8. Modeling Antibiotic Resistance in Bacterial Colonies Using Agent-Based Approach

    • James T. Murphy, Ray Walshe
    Pages 131-154

  9. Modeling the Spatial Pattern Forming Modules in Mitotic Spindle Assembly

    • Chaitanya A. Athale
    Pages 155-173

  10. Cell-Centred Modeling of Tissue Behaviour

    • Rod Smallwood
    Pages 175-194

  11. Interaction-Based Simulations for Integrative Spatial Systems Biology

    • Antoine Spicher, Olivier Michel, Jean-Louis Giavitto
    Pages 195-231

  12. Back Matter

    Pages 233-238
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Keywords

About this book

This book is intended as a communication platform to bridge the cultural, conceptual, and technological gap among the key systems biology disciplines of biology, mathematics, and information technology. To support this goal, contributors were asked to adopts an approach that appeals to audiences from different backgrounds.

Editors and Affiliations

  • Nano Systems Biology Research Group, Biomedical Sciences Research Institute, University of Ulster, Coleraine, United Kingdom

    Werner Dubitzky

  • Jack Birch Unit of Molecular Carcinogene, Department of Biology, University of York, York, United Kingdom

    Jennifer Southgate

  • Biomedical Sciences Research Institute, Biomedical Sciences Research Institute, University of Ulster, Coleraine, United Kingdom

    Hendrik Fuß

Bibliographic Information

  • Book Title: Understanding the Dynamics of Biological Systems

  • Book Subtitle: Lessons Learned from Integrative Systems Biology

  • Editors: Werner Dubitzky, Jennifer Southgate, Hendrik Fuß

  • DOI: https://doi.org/10.1007/978-1-4419-7964-3

  • Publisher: Springer New York, NY

  • eBook Packages: Biomedical and Life Sciences, Biomedical and Life Sciences (R0)

  • Copyright Information: Springer Science+Business Media, LLC 2011

  • Hardcover ISBN: 978-1-4419-7963-6Published: 20 January 2011

  • Softcover ISBN: 978-1-4899-8151-6Published: 29 November 2014

  • eBook ISBN: 978-1-4419-7964-3Published: 07 January 2011

  • Edition Number: 1

  • Number of Pages: XIV, 238

  • Topics: Systems Biology, Bioinformatics, Computer Appl. in Life Sciences

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