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Diseases of DNA Repair

  • Book
  • © 2010

Overview

  • Presents an updated detailed account of some important additional diseases of DNA repair
  • Aimed to maintain a balance between the DNA repair diseases that have been studied exhaustively, well-defined genetic defects in DNA repair system(s) and those diseases that shows a tangential association with DNA repair defects and hence more studies are warranted
  • Beneficial to the clinicians in treating their specialized cases

Part of the book series: Advances in Experimental Medicine and Biology (AEMB, volume 685)

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Table of contents (22 chapters)

Keywords

About this book

Since this book is geared to be used by varied groups of readers such as advanced students and instructors in the fields of biology and medicine, scientists and more importantly clinicians, it is considered important to provide brief accounts of the basics of DNA damage, repair, mutagenesis and cancer. The purpose of this book is to present an updated detailed account of some important additional diseases of DNA repair. It has not been possible to cover all the DNA repair deficient diseases in this volume, hence diseases such as Bloom’s syndrome, Werner’s syndrome, Nijmegen breakage syndrome, ataxia telangiectasia‑like disorder, RA D 50 deficiency, RIDDLE syndrome and others will be presented in a forthcoming volume.

Editors and Affiliations

  • School of Science and Technology, Nottingham Trent University, Nottingham, UK

    Shamim I. Ahmad

About the editor

Shamim Ahmad after obtaining his Master’s degree in Botany from Patna University, Bihar, India and his PhD in Molecular Genetics from Leicester University, England, joined Nottingham Polytechnic as Grade 1 lecturer and subsequently promoted to SL post. Nottingham Polytechnic subsequently became Nottingham Trent University where, after serving for about 35 years, he took early retirement to spend the remaining time writing books and conducting full‑time research. For more than three decades he worked on different areas of biology including thymineless death in bacteria, genetic control of nucleotide catabolism, development of anti‑AIDS drugs, control of microbial infection of burns, phages of thermophilic bacteria and microbial flora of Chernobyl after nuclear accident. But his primary interest, which started 25 years ago, is DNA damage and repair, particularly near UV photolysis of biological compounds, production of reactive oxygen species and their implications on human health including skin cancer and xeroderma pigmentosum. He is also investigating photolysis of non‑biological compounds such as 8‑methoxypsoralen+UVA, mitomycin C, and nitrogen mustard and their importance in psoriasis treatment and in Fanconi anemia. In 2003 he received a prestigious “Asian Jewel Award” in Britain for “Excellence in Education”. He is also the Editor of Molecular Mechanisms of Fanconi Anaemia, Molecular Mechanisms of Xeroderma Pigmentosum, Molecular Mechanisms of Ataxia Telangiectasia and Molecular Mechanisms of Cockayne Syndrome published by Landes Bioscience.

Bibliographic Information

  • Book Title: Diseases of DNA Repair

  • Editors: Shamim I. Ahmad

  • Series Title: Advances in Experimental Medicine and Biology

  • DOI: https://doi.org/10.1007/978-1-4419-6448-9

  • Publisher: Springer New York, NY

  • eBook Packages: Biomedical and Life Sciences, Biomedical and Life Sciences (R0)

  • Copyright Information: The Editor(s) (if applicable) and The Author(s), under exclusive license to Springer Science+Business Media, LLC, part of Springer Nature 2010

  • Hardcover ISBN: 978-1-4419-6447-2Published: 21 May 2010

  • Softcover ISBN: 978-1-4939-4104-9Published: 23 August 2016

  • eBook ISBN: 978-1-4419-6448-9Published: 11 January 2011

  • Series ISSN: 0065-2598

  • Series E-ISSN: 2214-8019

  • Edition Number: 1

  • Number of Pages: XXVII, 256

  • Topics: Human Genetics, Biomedicine general

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