The Neural Control of Sleep and Waking

1. Front Matter

   Pages i-xvi

   PDF

2. A Brief Synopsis of Neuroanatomy

   1. A Brief Synopsis of Neuroanatomy

      Pages 1-6

3. The First Half-Century: The Groundwork for the Science of Sleep and Waking Is Laid

   1. Front Matter

      Pages 7-7

      PDF

   2. Technological Developments

      Pages 9-26

   3. Early Research on Brain Mechanisms of Sleep and Waking

      Pages 27-31

4. The Second Half-Century: The Benefits Are Reaped

   1. Front Matter

      Pages 33-33

      PDF

   2. The Waking Brain

      1. The Discovery of the Ascending Reticular Activating System

         Pages 35-45

      2. The Neural Pathways That Produce Arousal

         Pages 47-52

5. The Second Half-Century: The Benefits Are Reaped

   1. Front Matter

      Pages 53-53

      PDF

   2. The Sleeping Brain: Slow-Wave Sleep

      1. Forebrain and Hindbrain Inhibition of the Reticular Activating System

         Pages 55-60

      2. EEG Synchrony and Behavioral Inhibition

         Pages 61-77

      3. Cellular Mechanisms and Neural Circuits That Produce Sleep

         Pages 79-84

      4. Sleep Factors

         Pages 85-91

      5. Sleep as a Circadian Rhythm

         Pages 93-101

6. The Second Half-Century: The Benefits Are Reaped

   1. Front Matter

      Pages 103-103

      PDF

   2. The Dreaming Brain: REM and Paradoxical Sleep

      1. The Discovery of REM Sleep

         Pages 105-112

      2. The Neural Control of REM Sleep

         Pages 113-126

7. The Functions and Disorders of Sleep and Waking

   1. Front Matter

      Pages 127-127

      PDF

   2. Theories of Sleep and Waking

      Pages 129-154

   3. Disorders of Sleep and Waking

      Pages 155-169

My first contact with “the other” Jerome Siegel came in 1973, when I moved to Los Angeles to do postdoctoral work at UCLA. My thesis work had been listed in a nationally available posting without any address. The Brain Inf- mation Service, thinking they knew where I was, listed “the other” Jerome Siegel’s Delaware address for reprint requests. I soon received a letter from Jerry along with the requests he had received and we have remained in c- tact ever since. I am occasionally reminded of my namesake when I meet a new colleague who is impressed that someone “so young” published a paper in Science in 1965 (one year out of high school, if it had been me). I entered the field in the early 1970s just as he left. My interests in REM sleep and brainstem mechanisms have been eerily similar to his (and he also did po- doctoral work at UCLA), so our research contributions can be distinguished easily only by my use of my middle initial (which has occasionally been om- ted from my publications). So, my namesake and I both have an interest in seeing to it that no one “brings shame to the name. ” The current work certainly fulfills that dictum. This is a very unusual book, both in its scope and in its approach to the - terial.

• Arousal
• anatomy
• biology
• brain
• electroencephalography (EEG)
• forebrain
• neuroanatomy
• physiology
• psychology

• Departments of Psychology and Biological Sciences, University of Delaware, Newark, USA

  Jerome Siegel

Policies and ethics