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Restorative Therapies in Parkinson's Disease

  • Book
  • © 2006

Overview

Editors:
  1. Patrik Brundin

    1. Department of Experimental Medical Science Wallenberg Neuroscience Center, Lund University, Lund, Sweden

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  2. C. Warren Olanow

    1. Department of Neurology, Mount Sinai School of Medicine, New York, USA

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  • Overview of state-of-the-art research for brain repair

  • Includes supplementary material: sn.pub/extras

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Table of contents (16 chapters)

  1. Front Matter

    Pages i-xxxi
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  2. Restorative Therapies for Parkinson's Disease: Current Status and Future Perspectives

    • Anders Björklund
    Pages 1-11

  3. Restorative Therapies for Parkinson's Disease: Ethical Issues

    • Gerard J. Boer
    Pages 12-49

  4. Evolution of Parkinson's Disease and Treatment Requirements: What New Treatments are Needed and the Role of Striatal Grafting

    • José A Obeso, Anthony E Lang
    Pages 50-64

  5. Clinical Trial Design Issues

    • Karl Kieburtz
    Pages 65-77

  6. Lessons Learned From Early Clinical Neural Grafting in Parkinson's Disease

    • Pierre Cesaro, Håkan Widner
    Pages 78-92

  7. Fetal Nigral Transplantation as a Therapy for Parkinson's Disease

    • C. W. Olanow, S. Fahn
    Pages 93-118

  8. Imaging of the Parkinsonian Brain in Relation to Restorative Therapy

    • A. Jon Stoessl, Vesna Sossi, David J. Brooks
    Pages 119-130

  9. Important Aspects of Surgical Methodology for Transplantation in Parkinson's Disease

    • Thomas B. Freeman, Patrik Brundin
    Pages 131-165

  10. Histopathological and Clinical Criteria for Analyzing Transplanted Human Dopamine Cells in Parkinson's Disease

    • Ole Isacson, Nicholas Lange, Oliver Cooper, Rosario Sanchez-Pernaute
    Pages 166-183

  11. Dyskinesias and Neural Grafting in Parkinson's Disease

    • M. Angela Cenci-Nilsson, Peter Hagell
    Pages 184-224

  12. Porcine Neural Xenotransplantation: Current Status

    • Roger A. Barker, Mark Sayles
    Pages 225-243

  13. Adult-Derived Stem Cells for Transplantation in Parkinson's Disease

    • Xinyu Zhao, D. Chichung Lie, Fred H. Gage
    Pages 244-268

  14. Embryonic Stem Cells for Grafting in Parkinson's Disease

    • Viviane Tabar, Lorenz Studer
    Pages 269-284

  15. Genetically Modified Cells as a Source for Grafting in Parkinson's Disease

    • Hyun-Jung Kim, Gesine Paul, Yu-Tzu Tai, Clive N. Svendsen
    Pages 285-296

  16. Delivery of GDNF for Parkinson's Disease: Transition of a Neuroprotective Treatment Strategy From Basic Sciences to Clinical Application

    • Deniz Kirik, Biljana Georgievska, Soshana Behrstock, Clive Niels Svendsen
    Pages 297-316

  17. In Vivo Gene Therapy as a Potential Treatment for Parkinson's Disease

    • Caryl E. Sortwell, Jeffrey H. Kordower
    Pages 317-344

  18. Back Matter

    Pages 345-365
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Keywords

About this book

Never in history has there been greater hope that novel experimental therapies can support significant restoration of brain function. The field of restorative therapies in Parkinson’s disease has passed the initial phase of pioneering experimental and clinical trials. There still does not exist restorative therapy that can be applied in large numbers of patients, but the initial trials have provided us with fundamental insight into the potential for plasticity in the diseased brain. This book gives an overview of the current state-of-the-art research for brain repair, what the challenges are and an indication of what research can provide for the next generation of people with Parkinson’s disease.

Editors and Affiliations

  • Department of Experimental Medical Science Wallenberg Neuroscience Center, Lund University, Lund, Sweden

    Patrik Brundin

  • Department of Neurology, Mount Sinai School of Medicine, New York, USA

    C. Warren Olanow

Bibliographic Information

  • Book Title: Restorative Therapies in Parkinson's Disease

  • Editors: Patrik Brundin, C. Warren Olanow

  • DOI: https://doi.org/10.1007/0-387-32823-2

  • Publisher: Springer New York, NY

  • eBook Packages: Biomedical and Life Sciences, Biomedical and Life Sciences (R0)

  • Copyright Information: Springer-Verlag US 2006

  • Hardcover ISBN: 978-0-387-29984-6Published: 05 July 2006

  • Softcover ISBN: 978-1-4899-9522-3Published: 19 September 2014

  • eBook ISBN: 978-0-387-32823-2Published: 31 August 2006

  • Edition Number: 1

  • Number of Pages: XVII, 365

  • Topics: Neurosciences, Neurology

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