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Introduction to Basics of Pharmacology and Toxicology

Volume 1: General and Molecular Pharmacology: Principles of Drug Action

  • Elucidates significant discoveries by Nobel Laureates in pharmacology
  • Provides extensive information on the principles governing drug action
  • Covers special topics in pharmacology that are hard to find elsewhere
  • Introduces readers to topics such as drug poisoning and toxicology through highly engaging chapters
  • Covers classical and cutting-edge molecular biology techniques employed in pharmacology

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Table of contents (34 chapters)

  1. Front Matter

    Pages i-xviii
  2. Historical Aspects of Drug Discovery

    1. Front Matter

      Pages 1-1
    2. Indian Contributions to Pharmacology

      • Sakthibalan Murugesan, Mangaiarkkarasi Adhimoolam
      Pages 41-57
  3. General Pharmacological Principles

    1. Front Matter

      Pages 59-59
    2. Sources and Nature of Drugs

      • Avinash Arivazhahan
      Pages 61-68
    3. Principles and Modes of Drug Administration

      • Avinash Arivazhahan
      Pages 69-79
    4. Drug Absorption and Bioavailability

      • Abialbon Paul
      Pages 81-88
    5. Drug Distribution

      • Abialbon Paul
      Pages 89-98
    6. Drug Metabolism

      • Mageshwaran Lakshmanan
      Pages 99-116
    7. Drug Elimination

      • Elavarasi Pichai, Mageshwaran Lakshmanan
      Pages 117-129
    8. Mechanisms of Drug Action

      • Abialbon Paul
      Pages 131-153
    9. Drug Transporters

      • Rekha Priyadarshini
      Pages 155-176
    10. Adverse Effects and Pharmacovigilance

      • Avinash Arivazhahan, Sushil Kiran Kunder
      Pages 177-196
    11. Drug Interactions

      • Heta Shah, Neel Jayesh Shah
      Pages 197-204
    12. Structure-Activity Relationships

      • Mageshwaran Lakshmanan
      Pages 205-219
  4. Special Topics in Pharmacology

    1. Front Matter

      Pages 221-221
    2. Drug Information

      • Nishanthi Anandabaskar
      Pages 223-234
    3. Chronopharmacology

      • Nishanthi Anandabaskar
      Pages 261-270

About this book

This book illustrates, in a comprehensive manner, the most crucial principles involved in pharmacology and allied sciences. The title begins by discussing the historical aspects of drug discovery, with up to date knowledge on Nobel Laureates in pharmacology and their significant discoveries. It then examines the general pharmacological principles - pharmacokinetics and pharmacodynamics, with in-depth information on drug transporters and interactions. In the remaining chapters, the book covers a definitive collection of topics containing essential information on the basic principles of pharmacology and how they are employed for the treatment of diseases.

Readers will learn about special topics in pharmacology that are hard to find elsewhere, including issues related to environmental toxicology and the latest information on drug poisoning and treatment, analytical toxicology, toxicovigilance, and the use of molecular biology techniques in pharmacology. The book offers a valuable resource for researchers in the fields of pharmacology and toxicology, as well as students pursuing a degree in or with an interest in pharmacology. 

Editors and Affiliations

  • Department of Pharmacology, Sri Venkateshwaraa Medical College Hospital and Research Centre (SVMCH & RC), Puducherry, India

    Gerard Marshall Raj

  • Department of Pharmacology, Jawaharlal Institute of Postgraduate Medical Education and Research (JIPMER), Puducherry, India

    Ramasamy Raveendran

About the editors

Dr. Gerard Marshall Raj. D holds an M.B.B.S. and M.D. in Pharmacology. Currently, he is working as an Assistant Professor at the Dept. of Pharmacology, Sri Venkateshwaraa Medical College Hospital & Research Centre, Puducherry, India. He has published two book chapters, one on ‘Intellectual Property Rights in Drug Development and Biotechnology’ in the book ‘Intellectual Property Issues in Biotechnology’ (CABI; ISBN: 9781780646534) and the other on ‘Intellectual Property Issues Surrounding Antimicrobial Agents’ in the book ‘Intellectual Property Issues in Microbiology’ (Springer-Nature; ISBN: 9789811374654). He was awarded the ‘Prof. M. N. Ghosh Gold Medal’ for outstanding performance during the M.D. Pharmacology course at JIPMER, Puducherry and has published many research articles, reviews, commentaries, case reports and letters-to-the-editor in peer-reviewed and indexed journals. 

Dr. Ramasamy Raveendran, Dean (Research) -cum- Professor (Senior Scale) and Head of Pharmacology, JIPMER, Puducherry, graduated from the University of Madras and obtained his M.D. degree in Pharmacology from JIPMER, Puducherry and his Diploma in Clinical Pharmacology from St Bartholomew’s Medical College, London, UK. With over 34 years of research and teaching experience, his main interests include Computer Assisted Learning (CAL) and toxicology. He has authored 55 research papers, 7 CAL software packages and 1 book. He has also conducted more than 50 workshops on research methodologies, biomedical communication and biostatistics throughout India. He was chief editor of the Indian Journal of Pharmacology from 2001 to 2006 and is currently editor-in-chief of the Journal of Pharmacology and Pharmacotherapeutics (since 2010). Further, as the Dean (Research) of JIPMER, he is coordinating all research activities at the premier institute. 


Bibliographic Information

  • Book Title: Introduction to Basics of Pharmacology and Toxicology

  • Book Subtitle: Volume 1: General and Molecular Pharmacology: Principles of Drug Action

  • Editors: Gerard Marshall Raj, Ramasamy Raveendran

  • DOI: https://doi.org/10.1007/978-981-32-9779-1

  • Publisher: Springer Singapore

  • eBook Packages: Biomedical and Life Sciences, Biomedical and Life Sciences (R0)

  • Copyright Information: Springer Nature Singapore Pte Ltd. 2019

  • Hardcover ISBN: 978-981-32-9778-4Published: 29 November 2019

  • Softcover ISBN: 978-981-32-9781-4Published: 29 November 2020

  • eBook ISBN: 978-981-32-9779-1Published: 16 November 2019

  • Edition Number: 1

  • Number of Pages: XVIII, 417

  • Number of Illustrations: 48 b/w illustrations, 39 illustrations in colour

  • Topics: Pharmaceutical Sciences/Technology, Pharmacy, Drug Resistance

Buy it now

Buying options

eBook USD 149.00
Price excludes VAT (USA)
  • Available as EPUB and PDF
  • Read on any device
  • Instant download
  • Own it forever
Softcover Book USD 199.99
Price excludes VAT (USA)
  • Compact, lightweight edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info
Hardcover Book USD 199.99
Price excludes VAT (USA)
  • Durable hardcover edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info

Tax calculation will be finalised at checkout

Other ways to access