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Oxidative Stress in Lung Diseases

Volume 2

  • Book
  • © 2020

Overview

  • Adopts a multidisciplinary approach, demonstrating cellular and molecular mechanisms associated with ROS-induced initiation and progression of a variety of lung diseases

  • Covers pathological aspects of oxidative stress induced initiation and progression of different types of lung disease, including COPD, asthma and their potential therapeutics known to date

  • Focuses upon the advances in therapies for various lung diseases, such as COPD, lung cancer and other pulmonary diseases

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Table of contents (22 chapters)

  1. General Aspects of Reactive Oxygen Species-Mediated Lung Diseases

  2. Chronic Lung Diseases

  3. Other Lung Diseases

Keywords

About this book

This is the second volume of the comprehensive, two-volume work on oxidative stress in lung diseases. Adopting a multidisciplinary approach, it demonstrates the cellular and molecular mechanisms associated with ROS (reactive oxygen species)-induced initiation and progression of a variety of lung diseases, such as COPD, emphysema, asthma, cystic fibrosis, occupational pulmonary diseases and pulmonary hypertension and discusses points for therapeutic intervention. The book also covers translational research and the latest research on prevention and therapeutics. Each chapter includes in-depth insights into the mechanisms associated with lung diseases and into identifying targets for drug development. Bridging the gap between fundamental and translational research, and examining applications in the biomedical and pharmaceutical industry, it is a thought- provoking read for basic and applied scientists engaged in biomedical research.




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Editors and Affiliations

  • Department of Biochemistry and Biophysics, University of Kalyani, Kalyani, India

    Sajal Chakraborti, Rita Ghosh, Tapati Chakraborti

  • Department of Internal Medicine, The Ohio State University, Columbus, USA

    Narasimham L. Parinandi

  • Apollo Hospitals Educational & Research Foundation (AHERF), Indraprastha Apollo Hospitals, New Delhi, India

    Nirmal K. Ganguly

About the editors

Prof. Sajal Chakraborti is a Professor of Biochemistry at the University of Kalyani, West Bengal, India. His research covers the role of proteases, oxidant and Ca2+ signalling in the pathogenesis of a variety of diseases. Prof. Chakraborti did is PhD from Calcutta University (1982) and DSc from Kalyani University (2014). He did his post- doctoral research at Johns Hopkins University, University of Utah and New York Medical College. He received DBT-Senior overseas research award for his research at the Brain Institute, University of Florida, Gainesville (1998-1999). He has been engaged in teaching and research in biochemistry for the past 40 years. He has published more than hundred original papers, 22 book chapters, 15 review articles and edited seven books published by Springer.

Dr. Tapati Chakraborti is a Professor of Biochemistry at the University of Kalyani, West Bengal, India. Her research focuses on the determination of the Mechanisms Associated with the Role of Proteases in the Oxidant-mediated Cellular Dysregulation of Pulmonary Vascular Endothelial and Smooth Muscle Cells. She received Ph.D. from the CSIR-Indian Institute of Chemical Biology (affiliated to Jadavpur University, Kolkata in the year 1992 and did post-doctoral research at the Brain Institute, University of Florida, Gainesville, Florida during 1999-2002.  Dr. Tapati Chakraborti has been actively involved in teaching and research for the past 30 years. She has published more than 80 original research papers, 18 book chapters, and 12 review articles. She also edited a book entitled “Proteases in human diseases” published by Springer in the year 2017.

Prof. Rita Ghosh is a Professor of Biophysics in the Department of Biochemistry and Biophysics, University of Kalyani, Kalyani, West Bengal, India. She did her MSc in Physics from Calcutta University and PhD from Saha Institute of Nuclear Physics, Kolkata. She did her post doctoral research at the Swiss Institute of Experimental Cancer Research, Lausanne, Switzerland (1991-1993). Her research covers mainly in the area of  cell biology..   She has been engaged in teaching and research for more than 30 years. She has published above 40 original research papers, review articles and books chapters.

 Prof. Nirmal K. Ganguly was the Director General of Indian Council of Medical Research (ICMR), New Delhi and the Director of PGIMER (Chandigarh) and National Institute of Biologicals (Noida). Dr. Ganguly is currently a Distinguished Professor, Global Health Strategies at New Delhi, India and the Chief Advisor of the Policy Centre for Biomedical Research, Translational Health Science & Technology Institute, Faridabad, India and at Ganga Ram Institute for Postgraduate Medical Education & Research (GRIPMER). Dr. Ganguly has published over 780 research papers and has mentored 130 doctoral students leading to the fulfillment of Ph.D. dissertations as the Doctoral Advisor/Joint Advisor.  Currently, Dr. Ganguly also focuses on the Immunological Basis of Cancer as a major area of his research.  Dr. Ganguly is a Fellow of the Imperial College Faculty of Medicine, London, the Royal College of Pathologists, London,the International Academy of Cardiovascular Sciences, Canada, the Third World Academy of Sciences, Italy, and the International Medical Sciences Academy, New Delhi. Dr. Ganguly is also a Fellow of all the National Academies of Sciences. He has received more than 119 awards, including 8 International and 111 National Awards. He has been honored with the prestigious Indian National Padma Bhushan Award presented to him by the President of India, on 26th January, 2008 in the field of Medicine.

Dr. Narasimham L Parinandi is currently an Associate Professor in Department of Internal Medicine and Division of Pharmacology, The Ohio State University, Columbus, Ohio. Dr. Parinandi earned his Ph.D. (1986) at the University of Toledo, Toledo, OH, USA.  He did his post doctoral research (1986-90) at the Hormel Institute, University of Minnesota, where he was associated with Prof. Harald Schmid (a celebrity in the area of lipid biochemistry) and  Prof. Ralph T. Holman (Member of the National Academy of Sciences, USA). He was a research scientist at the Johns Hopkins University School of Medicine (1998-2002). Dr. Parinandi also collaborated with Dr. Louis J. Ignarro, a recipient of the 1998 Nobel Prize in Physiology (for signaling properties of nitric oxide). He has published 120 original research papers, reviews, and book chapters, and edited a book on Free Radicals and Antioxidant Protocols with Prof. William Pryor, the legendary Free Radical and Lipid Peroxidation Scientist. Dr. Parinandi is an Associate Editor of Cell Biophysics & Biochemistry (Springer). Dr. Parinandi has teaching and mentoring experience of more than 37 years in the US universities and has mentored over 75 students in his laboratory at 4 major US universities.



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