Overview
Describes our current understanding of the biogenesis and function of peroxisomes
Examines the role of peroxisomes in human diseases and the latest diagnostic and therapeutic strategies
Discusses a range of hot topics in peroxisome research
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Table of contents (12 chapters)
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Biogenesis and Function of Peroxisome
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Dysfunction of Peroxisome and Human Disease
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Topics in Peroxisome Research
Keywords
About this book
This book provides readers with a comprehensive overview of peroxisomes and their role in human diseases. It starts by describing the history of peroxisome research and then examines in detail the current understanding of the biogenesis and function of peroxisomes. It then focuses on peroxisomal disorders and the involvement of peroxisomes in cancer and age-related diseases, discussing in detail the use of model organisms to elucidate the pathogenesis of peroxisomal disorders and the physiological importance of peroxisomal proteins. Further, the book examines diagnostic and therapeutic strategies in peroxisomal disorders as well as significant recent advances. Lastly, it addresses various topics in peroxisome research, including the isolation of peroxisomes from mammalian tissues and cells, the structural biology of peroxisomal proteins, the lipidomics of peroxisomal disorders, the value of exome sequencing, and neuropsychological testing in X-linked adrenoleukodystrophy. Given its scope, the book is a valuable resource for postgraduate students and researchers in the life sciences and clinicians in the fields of internal medicine, pediatrics, and neurology.
Editors and Affiliations
About the editors
Bibliographic Information
Book Title: Peroxisomes: Biogenesis, Function, and Role in Human Disease
Editors: Tsuneo Imanaka, Nobuyuki Shimozawa
DOI: https://doi.org/10.1007/978-981-15-1169-1
Publisher: Springer Singapore
eBook Packages: Biomedical and Life Sciences, Biomedical and Life Sciences (R0)
Copyright Information: Springer Nature Singapore Pte Ltd. 2019
Hardcover ISBN: 978-981-15-1168-4Published: 17 January 2020
Softcover ISBN: 978-981-15-1171-4Published: 17 January 2021
eBook ISBN: 978-981-15-1169-1Published: 16 January 2020
Edition Number: 1
Number of Pages: XII, 279
Number of Illustrations: 32 b/w illustrations, 33 illustrations in colour
Topics: Human Physiology, Cell Biology, Cell Physiology, Animal Biochemistry