Overview
Describes the role of zinc in regulating protein functions and as an intracellular and extracellular signaling factor
Explains the critical contributions of the zinc signal in health and a wide range of disorders
New edition reflecting all the latest advances in knowledge
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Table of contents (19 chapters)
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Front Matter
Keywords
About this book
This book, now in an extensively revised second edition, describes the crucial role of zinc signaling in biological processes on a molecular and physiological basis. Global leaders in the field review the latest knowledge, including the very significant advances in understanding that have been achieved since publication of the first edition. Detailed information is provided on all the essentials of zinc signaling, covering molecular aspects and the roles of zinc transporters, the zinc sensing receptor, and metallothioneins. Detection techniques for zinc signals, involving genetically encoded and chemical probes, are also described. The critical contributions of the zinc signal in maintaining health and the adverse consequences of any imbalance in the signal are then thoroughly addressed. Here, readers will find up-to-date information on the significance of the zinc signal in a wide range of conditions, including cardiovascular disorders, neurodegenerative diseases, diabetes, autoimmune diseases, inflammatory conditions, skin disease, osteoarthritis, and cancer. The book will be of value for researchers, clinicians, and advanced students.
Editors and Affiliations
About the editors
Associate professor. Taiho Kambe, Ph.D., Department of Applied Molecular Biology, Division of Integrated Life Science, Graduate School of Biostudies, Kyoto University, Japan.
Bibliographic Information
Book Title: Zinc Signaling
Editors: Toshiyuki Fukada, Taiho Kambe
DOI: https://doi.org/10.1007/978-981-15-0557-7
Publisher: Springer Singapore
eBook Packages: Biomedical and Life Sciences, Biomedical and Life Sciences (R0)
Copyright Information: Springer Nature Singapore Pte Ltd. 2019
Hardcover ISBN: 978-981-15-0556-0Published: 07 February 2020
Softcover ISBN: 978-981-15-0559-1Published: 26 August 2021
eBook ISBN: 978-981-15-0557-7Published: 13 December 2019
Edition Number: 2
Number of Pages: VIII, 413
Number of Illustrations: 14 b/w illustrations, 56 illustrations in colour
Topics: Biomedicine, general, Cell Physiology, Cell Biology, Biochemistry, general, Medical Biochemistry