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Aldehyde Dehydrogenases

From Alcohol Metabolism to Human Health and Precision Medicine

  • Book
  • © 2019

Overview

  • Covers the science of ALDH enzymes in relation to chronic disease processes
  • Provides the future therapeutic potentials of targeting ALDH
  • Demonstrates the unique value of targeting genetic polymorphism in ALDH enzymes in personalized medicine

Part of the book series: Advances in Experimental Medicine and Biology (AEMB, volume 1193)

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Table of contents (15 chapters)

Keywords

About this book

This volume covers the science of ALDH enzymes in relation to chronic disease processes and the future therapeutic potentials of targeting ALDH in these processes. It thoroughly reviews the roles of ALDH family in alcohol metabolism, as well as recent findings of their emerging roles in a variety of human pathologies such as cardiovascular diseases, diabetes, obesity, stroke, cancer, liver diseases and kidney diseases. Delicate contribution of ALDH enzymes in the therapeutics against chronic diseases is also discussed. It demonstrates the unique value of targeting genetic polymorphism in ALDH enzymes in personalized medicine. The book will appeal to scientists, physicians, graduate and professional students in the fields of ALDH enzymes, alcohol metabolism, cardiometabolic and other chronic diseases. Pharmaceutical and other companies developing new tools for cardiometabolic and chronic diseases treatment will also find this a valuable resource.


Editors and Affiliations

  • Department of Cardiology, Shanghai Institute of Cardiovascular Diseases, Zhongshan Hospital, Fudan University, Shanghai, China

    Jun Ren, Yingmei Zhang, Junbo Ge

About the editors

Prof. Jun Ren is Professor at the Department of Cardiology, Zhongshan Hospital, Fudan University, China, and Associate Dean for Research & Professor of Pharmacology, University of Wyoming College of Health Sciences, USA.
Prof. Yingmei Zhang is Professor at the Department of Cardiology, Zhongshan Hospital, Fudan University, China.
Prof. Junbo Ge is an Academician of the Chinese Academy of Sciences, and Professor at the Shanghai Institute of Cardiovascular Diseases, Zhongshan Hospital and Institute of Panvascular Medicine, Fudan University, Shanghai, China.

Bibliographic Information

  • Book Title: Aldehyde Dehydrogenases

  • Book Subtitle: From Alcohol Metabolism to Human Health and Precision Medicine

  • Editors: Jun Ren, Yingmei Zhang, Junbo Ge

  • Series Title: Advances in Experimental Medicine and Biology

  • DOI: https://doi.org/10.1007/978-981-13-6260-6

  • Publisher: Springer Singapore

  • eBook Packages: Biomedical and Life Sciences, Biomedical and Life Sciences (R0)

  • Copyright Information: Springer Nature Singapore Pte Ltd. 2019

  • Hardcover ISBN: 978-981-13-6259-0Published: 15 August 2019

  • Softcover ISBN: 978-981-13-6262-0Published: 16 August 2020

  • eBook ISBN: 978-981-13-6260-6Published: 31 July 2019

  • Series ISSN: 0065-2598

  • Series E-ISSN: 2214-8019

  • Edition Number: 1

  • Number of Pages: XX, 253

  • Number of Illustrations: 7 b/w illustrations, 20 illustrations in colour

  • Topics: Molecular Medicine, Enzymology, Human Physiology, Metabolic Diseases

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