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  • © 2018

Biochemistry and Cell Biology of Ageing: Part I Biomedical Science

  • Provides 17 chapters of up-to-date information on the biochemistry and cellular biology of aging processes in human cells
  • Explores a number of the current key areas of research in subcellular aging research
  • Examines topics such as mitochondrial aging, protein homeostasis and aging and the genetic processes that are involved in aging
  • Illustrates the roles of a variety of vitamins and minerals on aging and a number of other external factors (microbiological, ROS, inflammation, nutrition)
  • Presents contributions from leading experts in the field

Part of the book series: Subcellular Biochemistry (SCBI, volume 90)

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Table of contents (17 chapters)

  1. Front Matter

    Pages i-x
  2. Antioxidant Vitamins and Ageing

    • Irina Milisav, Samo Ribarič, Borut Poljsak
    Pages 1-23
  3. Autophagy: ‘Self-Eating’ Your Way to Longevity

    • Charlotte J. Pattison, Viktor I. Korolchuk
    Pages 25-47
  4. Key Age-Imposed Signaling Changes That Are Responsible for the Decline of Stem Cell Function

    • Melod Mehdipour, Yutong Liu, Chao Liu, Binod Kumar, Daehwan Kim, Ranveer Gathwala et al.
    Pages 119-143
  5. Creatine, Creatine Kinase, and Aging

    • Nathalie Sumien, Ritu A. Shetty, Eric B. Gonzales
    Pages 145-168
  6. Extracellular Matrix and Ageing

    • Helen L. Birch
    Pages 169-190
  7. Vitamin D and Ageing

    • Tom R. Hill, Antoneta Granic, Terence J. Aspray
    Pages 191-220
  8. Telomeres, Telomerase and Ageing

    • Gabriele Saretzki
    Pages 221-308
  9. Nuclear DNA Damage and Ageing

    • Kyriacos Agathangelou, Zisis Apostolou, George A. Garinis
    Pages 309-322
  10. Signal Transduction Pathways in Ageing

    • Cathy Slack, Jennifer Tullet
    Pages 323-350
  11. The Gut Microbiota and Ageing

    • Claire Maynard, David Weinkove
    Pages 351-371
  12. Nutrition and Ageing

    • Fiona C. Malcomson, John C. Mathers
    Pages 373-424
  13. Role/s of ‘Antioxidant’ Enzymes in Ageing

    • Elizabeth Veal, Thomas Jackson, Heather Latimer
    Pages 425-450
  14. B Vitamins and Ageing

    • Kathleen Mikkelsen, Vasso Apostolopoulos
    Pages 451-470
  15. Gene Expression, Epigenetics and Ageing

    • Babukrishna Maniyadath, Namrata Shukla, Ullas Kolthur-Seetharam
    Pages 471-504
  16. Glycobiology of Aging

    • Fabio Dall’Olio
    Pages 505-526

About this book

This new volume in the Subcellular Biochemistry series will focus on the biochemistry and cellular biology of aging processes in human cells. The chapters will be written by experts in their respective fields and will focus on a number of the current key areas of research in subcellular aging research. Main topics for discussion are mitochondrial aging, protein homeostasis and aging and the genetic processes that are involved in aging. There will also be chapters that are dedicated to the study of the roles of a variety of vitamins and minerals on aging and a number of other external factors (microbiological, ROS, inflammation, nutrition). This book will provide the reader with a state of the art overview of the subcellular aging field. This book will be published in cooperation with a second volume that will discuss the translation of the cell biology of aging to a more clinical setting and it is hoped that the combination of these two volumes will bring a deeper understanding of the links between the cell and the body during aging.

Editors and Affiliations

  • Institute of Molecular Physiology, Johannes Gutenberg University, Mainz, Germany

    J. Robin Harris

  • Newcastle University, Newcastle upon Tyne, UK

    Viktor I. Korolchuk

About the editors

Prof. J. Robin Harris is an Honorary Professor of the University of Mainz, he has broad biomedical science and electron microscopical  experience and is actively involved in scientific publishing. 

Dr. Viktor I. Korolchuk is a Reader in Molecular Cell Biology at Newcastle University and is actively involved in cellular autophagy studies.


Bibliographic Information

  • Book Title: Biochemistry and Cell Biology of Ageing: Part I Biomedical Science

  • Editors: J. Robin Harris, Viktor I. Korolchuk

  • Series Title: Subcellular Biochemistry

  • DOI: https://doi.org/10.1007/978-981-13-2835-0

  • Publisher: Springer Singapore

  • eBook Packages: Biomedical and Life Sciences, Biomedical and Life Sciences (R0)

  • Copyright Information: Springer Nature Singapore Pte Ltd. 2018

  • Hardcover ISBN: 978-981-13-2834-3Published: 05 March 2019

  • eBook ISBN: 978-981-13-2835-0Published: 18 February 2019

  • Series ISSN: 0306-0225

  • Series E-ISSN: 2542-8810

  • Edition Number: 1

  • Number of Pages: X, 526

  • Number of Illustrations: 8 b/w illustrations, 54 illustrations in colour

  • Topics: Human Physiology

Buy it now

Buying options

eBook USD 229.00
Price excludes VAT (USA)
  • Available as EPUB and PDF
  • Read on any device
  • Instant download
  • Own it forever
Hardcover Book USD 299.99
Price excludes VAT (USA)
  • Durable hardcover edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info

Tax calculation will be finalised at checkout

Other ways to access