Overview
- Covers various types of the perinatal stem cells
- Provides comprehensive description of the biological foundation and manufacturing of the perinatal stem cells
- Introduces clinical applications of the perinatal stem cells in different diseases
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Table of contents (13 chapters)
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Front Matter
Keywords
About this book
This book provides a comprehensive introduction to various types of perinatal stem cells. Given their unique regenerative abilities, stem cells offer a promising avenue in the treatment of degenerative diseases or injury.
Currently, the limitations of postnatal cell sources and expanding efficiency may limit autologous stem cell therapies. Although embryonic stem cells (ESCs) and induced pluripotent stem cells (iPSCs) can be cultured indefinitely ex vivo, and can differentiate into three germ layers, ethical issues, the teratoma formation of ESCs and oncogenic risk of iPSCs are major obstacles to their clinical application. More recently, perinatal stem cells have been isolated from the umbilical cord, Wharton’s Jelly, placenta, amniotic membrane and amniotic fluid, which are normally discarded as medical waste. This book, after describing perinatal stem cells in detail, introduces readers to the various types of perinatal stem cells, addressing their characterization, banking, quality control and stability. Importantly, it also reviews the clinical applications of perinatal stem cells to therapy of diseases. Accordingly, it offers a valuable resource for clinicians, researchers and graduate students alike.
Reviews
“The book offers detailed insights into the sources of perinatal stem cells and how to derive, multiply and store them. It is intended for researchers in stem cell biology, tissue engineering, regenerative medicine, and students in developmental/stem cell biology. … perinatal tissue derived mesenchymal stem cells are expected to play an important role, along with massive vaccination campaigns, in restoring human health in the coming years.” (Manuela Monti, European Journal of Histochemistry, Vol. 65, 2021)
Editors and Affiliations
About the editors
Zhong Chao Han is a professor and director at the State Key Lab of Experimental Hematology, Institute of Hematology and Blood Diseases Hospital, Chinese Academy of Medical Sciences; Tsuneo A Takahashi is a visiting professor at the Institute for Frontier Medical Sciences, Kyoto University; Zhibo Han is an associate professor at the State Key Lab of Experimental Hematology, Institute of Hematology and Blood Diseases Hospital, Chinese Academy of Medical Sciences.
Bibliographic Information
Book Title: Perinatal Stem Cells
Book Subtitle: Biology, Manufacturing and Translational Medicine
Editors: Zhong Chao Han, Tsuneo A. Takahashi, Zhibo Han, Zongjin Li
DOI: https://doi.org/10.1007/978-981-13-2703-2
Publisher: Springer Singapore
eBook Packages: Medicine, Medicine (R0)
Copyright Information: Springer Nature Singapore Pte Ltd. 2019
Hardcover ISBN: 978-981-13-2702-5Published: 25 March 2019
eBook ISBN: 978-981-13-2703-2Published: 06 March 2019
Edition Number: 1
Number of Pages: VI, 173
Number of Illustrations: 2 b/w illustrations, 8 illustrations in colour
Topics: Reproductive Medicine, Obstetrics/Perinatology/Midwifery, Stem Cells, Regenerative Medicine/Tissue Engineering