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Proteomics of Peroxisomes

Identifying Novel Functions and Regulatory Networks

  • Provides a comprehensive, state-of-the-art overview of proteomic analysis of peroxisomes - a field that has seen many recent developments
  • Incorporates a wealth of research on the latest proteomics of peroxisomes derived from mammalian, Drosophila, fungal, and plant origin
  • Presents contributions from leading experts in the field

Part of the book series: Subcellular Biochemistry (SCBI, volume 89)

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Table of contents (21 chapters)

  1. Front Matter

    Pages i-xiii
  2. Mass Spectrometry-Based Organelle Proteomics

    1. Front Matter

      Pages 1-1
    2. Proteome of Plant Peroxisomes

      • Ronghui Pan, Jianping Hu
      Pages 3-45
    3. Defining the Mammalian Peroxisomal Proteome

      • Eden Yifrach, Sven Fischer, Silke Oeljeklaus, Maya Schuldiner, Einat Zalckvar, Bettina Warscheid
      Pages 47-66
    4. Fungal Peroxisomes Proteomics

      • Xin Chen, Chris Williams
      Pages 67-83
    5. The Craft of Peroxisome Purification—A Technical Survey Through the Decades

      • Markus Islinger, Andreas Manner, Alfred Völkl
      Pages 85-122
  3. Predicting Peroxisomal Proteomes

    1. Front Matter

      Pages 123-123
    2. Prediction of Peroxisomal Matrix Proteins in Plants

      • Sigrun Reumann, Gopal Chowdhary
      Pages 125-138
    3. The Obvious and the Hidden: Prediction and Function of Fungal Peroxisomal Matrix Proteins

      • Johannes Freitag, Thorsten Stehlik, Alina C. Stiebler, Michael Bölker
      Pages 139-155
    4. Multiple Localization by Functional Translational Readthrough

      • Kristina Bersch, Ignacio Lobos Matthei, Sven Thoms
      Pages 201-219
    5. Evolution of the Peroxisomal Proteome

      • Toni Gabaldón
      Pages 221-233
    6. Peroxisome Protein Prediction in Drosophila melanogaster

      • Matthew Anderson-Baron, Andrew J. Simmonds
      Pages 235-258
  4. Analysis of Peroxisome Proteome Interaction Networks

    1. Front Matter

      Pages 259-259
    2. Using Pull Down Strategies to Analyze the Interactome of Peroxisomal Membrane Proteins in Human Cells

      • Jessica Klümper, Silke Oeljeklaus, Bettina Warscheid, Ralf Erdmann, Wolfgang Schliebs
      Pages 261-285
    3. The Proteome of Fruit Peroxisomes: Sweet Pepper (Capsicum annuum L.) as a Model

      • José M. Palma, Paz Álvarez de Morales, Luis A. del Río, Francisco J. Corpas
      Pages 323-341
  5. Peroxisomes in Relation to Other Subcellular Compartments

    1. Front Matter

      Pages 343-343
    2. Peroxisomes and Their Central Role in Metabolic Interaction Networks in Humans

      • Ronald J. A. Wanders, Hans R. Waterham, Sacha Ferdinandusse
      Pages 345-365

About this book

This new edited volume in the Springer Subcellular Biochemistry Series presents a comprehensive, state-of-the-art overview of the proteomics of peroxisomes derived from mammalian, Drosophila, fungal, and plant origin, and contains contributions from leading experts in the field. 

The development of sensitive proteomics and mass spectrometry technologies, combined with bioinformatics approaches now allow the identification of low-abundance and transient peroxisomal proteins and permits to identify the complete proteome of peroxisomes, with the consequent increase of our knowledge of the metabolic and regulatory networks of these important cellular organelles. The book lines-up with these developments and is organized in four sections including: (i) mass spectrometry-based organelle proteomics; (ii) prediction of peroxisomal proteomes; (iii) analysis of peroxisome proteome interaction networks; and (iv) peroxisomes in relation to other subcellular compartments.

The editor Luis A. del Río is Professor ad honorem of the Spanish National Research Council (CSIC) in the Group of Antioxidants, Free Radicals and Nitric Oxide in Biotechnology, Food and Agriculture, Department of Biochemistry and Cell & Molecular Biology of Plants, at the Estación Experimental del Zaidín, Granada, Spain. Del Río’s research group focuses on the metabolism of reactive oxygen species (ROS), reactive nitrogen species (RNS) and antioxidants in plant peroxisomes, and the ROS- and RNS-dependent role of peroxisomes in plant cell signalling. 

The editor Michael Schrader is Professor of Cell Biology & Cytopathology in the Department of Biosciences at the University of Exeter, UK. Using mammalian peroxisomes as model organelles, Prof. Schrader and his team aim to unravel the molecular machinery and signalling pathways that mediate and regulate the formation, dynamics and abundance of these medically relevant cellular compartments.

Editors and Affiliations

  • Department of Biochemistry, Cell and Molecular Biology of Plants, Estación Experimental del Zaidín, CSIC, Granada, Spain

    Luis A. del Río

  • Department of Biosciences, University of Exeter, Exeter, UK

    Michael Schrader

Bibliographic Information

Buy it now

Buying options

eBook USD 219.00
Price excludes VAT (USA)
  • Available as EPUB and PDF
  • Read on any device
  • Instant download
  • Own it forever
Softcover Book USD 279.99
Price excludes VAT (USA)
  • Compact, lightweight edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info
Hardcover Book USD 279.99
Price excludes VAT (USA)
  • Durable hardcover edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info

Tax calculation will be finalised at checkout

Other ways to access