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  • © 2018

Drosophila Models for Human Diseases

  • Discusses specific and commonly used techniques involving the Drosophila model
  • Provides not only reviews but also protocols commonly used in laboratories related to each subject
  • Equips designers to develop a screening kit for new medicines using the Drosophila model

Part of the book series: Advances in Experimental Medicine and Biology (AEMB, volume 1076)

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Table of contents (16 chapters)

  1. Front Matter

    Pages i-x
  2. Drosophila as a Model Organism

    • Masamitsu Yamaguchi, Hideki Yoshida
    Pages 1-10
  3. Adult Intestine Aging Model

    • Koji Takeda, Takashi Okumura, Kiichiro Taniguchi, Takashi Adachi-Yamada
    Pages 11-23
  4. Parkinson’s Disease Model

    • Vuu My Dung, Dang Thi Phuong Thao
    Pages 41-61
  5. Repeat Expansion Disease Models

    • Morio Ueyama, Yoshitaka Nagai
    Pages 63-78
  6. Amyotrophic Lateral Sclerosis Model

    • Yumiko Azuma, Ikuko Mizuta, Takahiko Tokuda, Toshiki Mizuno
    Pages 79-95
  7. Drosophila Charcot-Marie-Tooth Disease Models

    • Masamitsu Yamaguchi, Hiroshi Takashima
    Pages 97-117
  8. Muscular Dystrophy Model

    • Saranyapin Potikanond, Wutigri Nimlamool, Jasprien Noordermeer, Lee G. Fradkin
    Pages 147-172
  9. Drosophila As a Cancer Model

    • Masato Enomoto, Carmen Siow, Tatsushi Igaki
    Pages 173-194
  10. From Drosophila Blood Cells to Human Leukemia

    • Manon Boulet, Marion Miller, Laurence Vandel, Lucas Waltzer
    Pages 195-214
  11. Drosophila Models to Investigate Insulin Action and Mechanisms Underlying Human Diabetes Mellitus

    • Yoshihiro H. Inoue, Hiroka Katsube, Yukiko Hinami
    Pages 235-256
  12. Humanized Flies and Resources for Cross-Species Study

    • Toshiyuki Takano-Shimizu-Kouno, Takashi Ohsako
    Pages 277-288
  13. Designs for Flies + of Mice and Men: Design Approaches to Drosophila melanogaster

    • Julia Cassim, Frank Kolkman, Marcel Helmer
    Pages 289-305
  14. Back Matter

    Pages 307-308

About this book

Most biological pathways, physical and neurological properties are highly conserved between humans and Drosophila and nearly 75% of human disease-causing genes have a functional homologue in Drosophila. This volume provides recent advances in Drosophila models for various human diseases, with each chapter providing a review of studies involving Drosophila models, as well as detailed protocols commonly used in laboratories. Starting with a review of Drosophila’s value as a highly tractable model organism for studying human diseases, subsequent chapters present Drosophila models for specific human diseases.
The book provides a useful resource for all scientists who are starting to use the Drosophila model in their studies, and for researchers working in the pharmaceutical industry and using new screening models to develop new medicines for various diseases. 

Editors and Affiliations

  • Department of Applied Biology, Kyoto Institute of Technology, Kyoto, Japan

    Masamitsu Yamaguchi

About the editor

Masamitsu Yamaguchi received his PhD from Osaka University and is currently a Professor of Applied Biology, Kyoto Institute of Technology. He is a former director of the Advanced Insect Research Promotion Center at Kyoto Institute of Technology. 

Bibliographic Information

Buy it now

Buying options

eBook USD 149.00
Price excludes VAT (USA)
  • Available as EPUB and PDF
  • Read on any device
  • Instant download
  • Own it forever
Softcover Book USD 199.99
Price excludes VAT (USA)
  • Compact, lightweight edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info
Hardcover Book USD 199.99
Price excludes VAT (USA)
  • Durable hardcover edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info

Tax calculation will be finalised at checkout

Other ways to access