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  • Book
  • © 2018

Single Cell Biomedicine

  • Focuses on various detection targets applied in single cell studies
  • Includes the methods newly developed
  • Highlights the importance and potential of single cell biomedicine in the development and validation of precision medicine strategies

Part of the book series: Advances in Experimental Medicine and Biology (AEMB, volume 1068)

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Table of contents (16 chapters)

  1. Front Matter

    Pages i-vi
  2. Can the Single Cell Make Biomedicine Different?

    • Yuming Wang, Li Li, Xiangdong Wang, Jianqian Gu
    Pages 1-6
  3. Single-Cell Non-coding RNA in Embryonic Development

    • Qiang Fu, Chuan-Jiang Liu, Zhen-Sheng Zhai, Xu Zhang, Tao Qin, Hong-Wei Zhang
    Pages 19-32
  4. High Throughput Single Cell RNA Sequencing, Bioinformatics Analysis and Applications

    • Xiaoyun Huang, Shiping Liu, Liang Wu, Miaomiao Jiang, Yong Hou
    Pages 33-43
  5. Circulating Tumor Cells: The Importance of Single Cell Analysis

    • D. Heymann, M. Téllez-Gabriel
    Pages 45-58
  6. Super-Resolution Fluorescence Microscopy for Single Cell Imaging

    • Han Feng, Xiaobo Wang, Zhiwei Xu, Xiaoju Zhang, Yongju Gao
    Pages 59-71
  7. Therapeutic Antibody Discovery in Infectious Diseases Using Single-Cell Analysis

    • Alexandria Voigt, Touyana Semenova, Janet Yamamoto, Veronique Etienne, Cuong Q. Nguyen
    Pages 89-102
  8. Single Cell Genetics and Epigenetics in Early Embryo: From Oocyte to Blastocyst

    • Yubao Wei, Helong Zhang, Qian Wang, Cuilian Zhang
    Pages 103-117
  9. The Potential Roles and Advantages of Single Cell Sequencing in the Diagnosis and Treatment of Hematological Malignancies

    • Mingyue Shi, Xiaoyan Dong, Lei Huo, Xiaobin Wei, Fang Wang, Kai Sun
    Pages 119-133
  10. Application of Single Cell Sequencing in Cancer

    • Lan Yu, Hua Zhao, Li Meng, Cuilian Zhang
    Pages 135-148
  11. Detection and Application of RNA Editing in Cancer

    • Mengjia Qian, Claudio Spada, Xiangdong Wang
    Pages 159-170
  12. Roles of Single Cell Systems Biomedicine in Lung Diseases

    • Yiming Zeng, Xiaoyang Chen, Xiangdong Wang
    Pages 177-185
  13. The Significance of Single-Cell Biomedicine in Stem Cells

    • Weishan Zhuge, Furong Yan, Zhitu Zhu, Xiangdong Wang
    Pages 187-195

About this book

The book focuses on various detection targets applied in single cell studies, including tumor tissue cells, circulating tumor cells (CTCs), disseminated tumor cells (DTCs), circulating tumor DNA (ctDNA), cell-free DNA (cfDNA) and cancer stem cells (CSCs). It also discusses and compares detection methods using these detection targets in different fields to reveal single cell biomedical functions. The volume focuses not only on the methods already been established and validated, and also the methods newly developed. The book also highlights the importance and potential of single cell biomedicine in the development and validation of precision medicine strategies. It is useful for researchers and students in the field of cell biology, molecular medicine and precision medicine etc.

Editors and Affiliations

  • Henan Provincial People’s Hospital, Zhengzhou, China

    Jianqin Gu

  • Shanghai Institute of Clinical Bioinformatics, Zhongshan Hospital, Fudan University, Shanghai, China

    Xiangdong Wang

About the editors

Dr. Jianqing Gu is Professor and President of Henan Province People Hospital, Zhengzhou, Henan Province, China.

Dr. Xiangdong Wang is Distinguished Professor of Medicine, Director of Shanghai Institute of Clinical Bioinformatics, Director of Fudan University Center for Clinical Bioinformatics, Deputy Director of Shanghai Respiratory Research Institute, Director of Biomedical Research Center, Fudan University Zhongshan Hospital, Shanghai, China;

Bibliographic Information

  • Book Title: Single Cell Biomedicine

  • Editors: Jianqin Gu, Xiangdong Wang

  • Series Title: Advances in Experimental Medicine and Biology

  • DOI: https://doi.org/10.1007/978-981-13-0502-3

  • Publisher: Springer Singapore

  • eBook Packages: Biomedical and Life Sciences, Biomedical and Life Sciences (R0)

  • Copyright Information: Springer Nature Singapore Pte Ltd. 2018

  • Hardcover ISBN: 978-981-13-0501-6Published: 12 July 2018

  • Softcover ISBN: 978-981-13-4434-3Published: 19 January 2019

  • eBook ISBN: 978-981-13-0502-3Published: 25 June 2018

  • Series ISSN: 0065-2598

  • Series E-ISSN: 2214-8019

  • Edition Number: 1

  • Number of Pages: VI, 195

  • Number of Illustrations: 33 b/w illustrations, 61 illustrations in colour

  • Topics: Molecular Medicine, Cell Biology

Buy it now

Buying options

eBook USD 99.00
Price excludes VAT (USA)
  • Available as EPUB and PDF
  • Read on any device
  • Instant download
  • Own it forever
Softcover Book USD 129.99
Price excludes VAT (USA)
  • Compact, lightweight edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info
Hardcover Book USD 179.99
Price excludes VAT (USA)
  • Durable hardcover edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info

Tax calculation will be finalised at checkout

Other ways to access