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Cell Biology of the Ovary

Stem Cells, Development, Cancer, and Clinical Aspects

  • Book
  • © 2018

Overview

Editors:
  1. Hidetaka Katabuchi

    1. Department of Obstetrics and Gynecology, Faculty of Life Sciences, Kumamoto University, Kumamoto, Japan

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  2. Takashi Ohba

    1. Department of Obstetrics and Gynecology, Faculty of Life Sciences, Kumamoto University, Kumamoto, Japan

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  3. Takeshi Motohara

    1. Department of Obstetrics and Gynecology, Faculty of Life Sciences, Kumamoto University, Kumamoto, Japan

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  • Provides latest insights into the ovary from basic to clinical aspects

  • Reveals recent findings on ovarian-related cells

  • Enriches understanding of stem cell biology of the ovary

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Table of contents (12 chapters)

  1. Front Matter

    Pages i-viii
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  2. Reconstitution of Germ Cell Development In Vitro

    • Shihori Yokobayashi, Mitinori Saitou
    Pages 1-19

  3. The Role of Hedgehog-BMP4 Signaling in the Patterning of Coelomic Mesoderm and the Onset of Gonadogenesis

    • Takashi Yoshino
    Pages 21-33

  4. Regulation of Metabolic Pathways in Steroidogenic Cells by Ad4BP/SF-1

    • Ken-ichirou Morohashi, Miki Inoue, Bing Li, Takashi Baba
    Pages 35-43

  5. Role of Lgr5-Expressing Stem Cells in Epithelial Renewal and Cancer in the Reproductive Tract

    • Annie Ng, Nick Barker
    Pages 45-59

  6. Tumor-Initiating Cells in Ovarian Cancer

    • Sharmila A. Bapat
    Pages 61-71

  7. Emerging Role of CD44 Variant 6 in Driving the Metastatic Journey of Ovarian Cancer Stem Cells

    • Takeshi Motohara, Hidetaka Katabuchi
    Pages 73-88

  8. Clinical Management of Primary Ovarian Insufficiency

    • Yoshinori Okamura
    Pages 89-99

  9. Rescue for Primary Ovarian Insufficiency

    • Kyu Sup Lee
    Pages 101-112

  10. Current Status of Ovarian Tissue Vitrification as a Fertility Preservation for the Young Cancer Patients

    • Nao Suzuki
    Pages 113-121

  11. Molecular Pathogenesis of Ovarian Cancer: An Inextricable Maze

    • Masaki Mandai
    Pages 123-134

  12. Clinical Management of Epithelial Ovarian Cancer

    • Yusuke Kobayashi, Hiroyuki Nomura, Fumio Kataoka, Eiichiro Tominaga, Kouji Banno, Daisuke Aoki
    Pages 135-151

  13. Molecular Targeted Therapy for Epithelial Ovarian Cancer

    • Hironori Tashiro, Hidetaka Katabuchi
    Pages 153-166
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Keywords

About this book

This unique compilation focuses on a very curious organ, the ovary. There are still many unknown facts about the origins of ovarian tissue and ovarian cancer, and each chapter describes in detail the latest insights into the ovary from basic to clinical aspects. Expert authors reveal the most recent findings on ovariogenesis and ovarian carcinogenesis by shedding light on stem cell biology for the ovarian surface epithelial cells or primordial germ cells. Readers will greatly increase their understanding of the relevance of the cells that constitute the ovary, which is of vast significance in comprehending the occurrence mechanism of ovarian tissue and ovarian cancer. In this way the book covers a wide range of fields concerned with the ovary. This work benefits not only gynecologists and obstetricians, but also basic researchers in the field of stem cell biology and all clinicians who are involved in the management of fertility preservation or ovarian cancer.  

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Editors and Affiliations

  • Department of Obstetrics and Gynecology, Faculty of Life Sciences, Kumamoto University, Kumamoto, Japan

    Hidetaka Katabuchi, Takashi Ohba, Takeshi Motohara

About the editors

Dr. Hidetaka Katabuchi,

Professor and Chairman,

Department of Obstetrics and Gynecology,

Faculty of Life Sciences,

Kumamoto University


Dr. Takashi Ohba,

Associate Professor,

Department of Obstetrics and Gynecology,

Faculty of Life Sciences,

Kumamoto University

  

Dr. Takeshi Motohara,

Assistant Professor,

Department of Obstetrics and Gynecology,

Faculty of Life Sciences,

Kumamoto University

Bibliographic Information

  • Book Title: Cell Biology of the Ovary

  • Book Subtitle: Stem Cells, Development, Cancer, and Clinical Aspects

  • Editors: Hidetaka Katabuchi, Takashi Ohba, Takeshi Motohara

  • DOI: https://doi.org/10.1007/978-981-10-7941-2

  • Publisher: Springer Singapore

  • eBook Packages: Medicine, Medicine (R0)

  • Copyright Information: Springer Nature Singapore Pte Ltd 2018

  • Hardcover ISBN: 978-981-10-7940-5Published: 28 May 2018

  • Softcover ISBN: 978-981-13-4023-9Published: 16 December 2018

  • eBook ISBN: 978-981-10-7941-2Published: 11 May 2018

  • Edition Number: 1

  • Number of Pages: VIII, 166

  • Number of Illustrations: 8 b/w illustrations, 24 illustrations in colour

  • Topics: Gynecology, Oncology, Reproductive Medicine

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