Management of Peritoneal Metastases- Cytoreductive Surgery, HIPEC and Beyond

1. Front Matter

   Pages i-xi

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2. Principles of Cytoreductive Surgery and Hyperthermic Intraperitoneal Chemotherapy

   1. Front Matter

      Pages 1-1

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   2. Evolving Role of CRS and HIPEC: Current Indications

      • Firoz Rajan, Aditi Bhatt

      Pages 3-14

   3. Role of HIPEC in the Prevention of Peritoneal Metastasis from Colorectal, Gastric and Appendiceal Cancer

      • Ramakrishnan Ayloor Seshadri, Akash Meinte Mehta

      Pages 15-30

   4. Cytoreductive Surgery for Peritoneal Metastases: Principles and Techniques

      • Aditi Bhatt, Sanket Mehta

      Pages 31-77

   5. HIPEC Methodology, Comparison of Techniques, and Drug Regimens: Is There a Need for Standardization?

      • K. Van der Speeten, L. Lemoine

      Pages 79-102

   6. Early Postoperative Intraperitoneal Chemotherapy: Current Role and Future Perspectives

      • T. Douchy, L. Lemoine, K. Van der Speeten

      Pages 103-133

   7. Imaging of Peritoneal Cancers

      • Stephanie Nougaret

      Pages 135-145

   8. Diagnostic Laparoscopy for the Evaluation of Peritoneal Metastases

      • Almog Ben-Yaacov, Joseph Dux, Aviram Nissan

      Pages 147-160

   9. Combined Resection Liver Metastases and Peritoneal Metastases

      • Arie Ariche, Dan Aderka, Almog Ben-Yaacov, Aviram Nissan

      Pages 161-179

   10. Management of Complications of CRS and HIPEC

       • Aditi Bhatt, Akash M. Mehta

       Pages 181-217

3. Disease Specific Applications of Cytoreductive Surgery and HIPEC

   1. Front Matter

      Pages 219-219

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   2. Cytoreductive Surgery and Intraperitoneal Chemotherapy for Advanced Epithelial Ovarian Cancer

      • Kayomarz Sethna, Shabber Zaveri, Aditi Bhatt

      Pages 221-252

   3. Surgical Management of Recurrent Epithelial Ovarian Cancer

      • Aditi Bhatt, Naoual Bakrin, Olivier Glehen

      Pages 253-280

   4. Multimodality Treatment for Colorectal Peritoneal Metastases

      • Aditi Bhatt, Sanket Mehta, François Quénet

      Pages 281-316

   5. Pseudomyxoma Peritonei Arising from Epithelial Appendiceal Tumours

      • Aditi Bhatt, Guillaume Passot, Olivier Glehen

      Pages 317-346

   6. Intraperitoneal Chemotherapy for Gastric Cancer

      • Mayank Jain, Shivendra Singh

      Pages 347-359

   7. Malignant Peritoneal Mesothelioma

      • Elizabeth Poli, Ashvin Rangole, Kiran K. Turaga

      Pages 361-368

   8. Rare Indications for Cytoreductive Surgery and Hyperthermic Intraperitoneal Chemotherapy

      • Aditi Bhatt, Ramakrishnan Ayloor Seshadri

      Pages 369-432

   9. Clinical Trials in CRS and HIPEC: Ongoing Trials and Future Directives

      • William F. Morano, Wilbur B. Bowne, Jesus Esquivel

      Pages 433-445

The widespread acceptance among the oncology community at large of cytoreductive surgery and HIPEC as a potentially curative treatment for peritoneal metastases has paved the way for innovative new therapies that could benefit a larger proportion of patients. Much has been and continues to be published on this subject.

This book provides comprehensive reviews on the various aspects of managing peritoneal metastases. The authors highlight essential practical issues that surgical oncologists encounter in their day-to-day practice, and try to before provide evidence based answers to address them. All chapters were written and/or reviewed by leading experts in this field.

• Peritoneal surface malignancies
• Cytoreductive surgery
• HIPEC
• EPIC
• Malignant peritoneal mesothelioma
• surgical oncology
• abdominal surgery

• Department of Surgical Oncology, Fortis Hospital, Bangalore, India

  Aditi Bhatt

''Dr. Aditi Bhatt is a Surgical oncologist specializing in the management of peritoneal surface malignancies. She has done her surgical oncology training from the Gujarat Cancer Research Institute in Ahmedabad, India and has further pursued a fellowship in peritoneal surface malignancies at Institut Gustave Roussy, Paris, France. She has been pursuing peritoneal surface oncology as a speciality for seven years. She was associate editor with Dr. Paul H. Sugarbaker for the special issue of the Indian Journal of Surgical Oncology on peritoneal surface malignancies in 2016. Dr. Aditi is currently involved in developing a robust system for collection and publication of Indian data pertaining to the management of peritoneal metastases and conducting multi-institutional studies.  Here specific areas of interest are pseudomyoma peritonei and other rare peritoneal tumors and ovarian cancer.'

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