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Hormone Therapy and Castration Resistance of Prostate Cancer

  • Elucidates the current status of hormone therapy for prostate cancer

  • Clarifies the differences between the evidence from Japan and that from Western countries on hormone therapy for prostate cancer

  • Broadens the reader’s understanding of castration-resistant prostate cancer

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Table of contents (43 chapters)

  1. Front Matter

    Pages i-viii
  2. Introduction

    • Yoichi Arai, Osamu Ogawa
    Pages 1-2
  3. Recent Trends in Hormone Therapy for Prostate Cancer in Japan

    • Mizuki Onozawa, Hideyuki Akaza
    Pages 3-11
  4. Impact of GnRH Antagonist and LHRH Agonist on the Gonadal Axis

    • Yoshiyuki Miyazawa, Yoshitaka Sekine, Kazuhiro Suzuki
    Pages 31-40
  5. Adrenal Androgen in Prostate Cancer

    • Yasuhiro Shibata
    Pages 51-58
  6. Intermittent ADT for Prostate Cancer

    • Koichiro Akakura
    Pages 59-67
  7. Ethnic Variation in Clinical Outcomes of Hormone Therapy for Prostate Cancer

    • Takashi Fukagai, Masashi Morita, Robert G. Carlile, John L. Lederer, Thomas Namiki
    Pages 77-88
  8. Complications of ADT for Prostate Cancer: Hot Flashes

    • Hideki Sakai, Tomoaki Hakariya
    Pages 133-139
  9. Bone Scan Index as a Biomarker of Bone Metastasis

    • Kenichi Nakajima, Lars Edenbrandt
    Pages 165-174

About this book

This comprehensive reference expounds the current state of hormone therapy and castration resistance of prostate cancer (PCa). Previously, the incidence of PCa in Asian countries was relatively low, but it has been increasing dramatically in recent years. Although most of the new cases are diagnosed in early stages, a significant proportion of patients receive hormone therapy for metastatic disease or for relapse after local treatment. Thus the situation has gradually changed toward earlier and longer use of hormone therapy. The malignancy finally forms castration-resistant prostate cancer (CRPC) despite the lack of testicular androgen. With advances in understanding of the molecular basis of hormone dependence and CRPC, many new androgen receptor-targeted agents have emerged.

During the last decade, much evidence on hormone therapy has been accumulated in Japan. Interestingly, some of these findings are different from those reported from Western countries, suggesting ethnic variation in the outcome of hormone therapy. In the chapters of this book, expert authors provide exhaustive interpretations of the evidence recently reported from Japan and provide important Asian perspectives on hormone therapy for PCa. This work benefits not only Asian urologists but also their Western counterparts and all physicians and medical personnel who are involved in the treatment of PCa.

Reviews

“This is a comprehensive review of the use of androgen deprivation as treatment for men with prostate cancer. … This is a high quality review of the use of ADT in prostate cancer treatment and is a useful resource for any physician or practitioner interested in understanding the use of ADT in men with prostate cancer.” (James R. Mark, Doody's Book Reviews, December 7, 2018)

Editors and Affiliations

  • Department of Urology, Tohoku University School of Medicine, Sendai, Japan

    Yoichi Arai

  • Department of Urology, Kyoto University Graduate School of Medicine, Kyoto, Japan

    Osamu Ogawa

About the editors

Dr. Yoichi Arai,

Professor and Chairman,

Department of Urology,

Tohoku University School of Medicine

 

Dr. Osamu Ogawa,

Professor and Chairman,

Department of Urology,

Kyoto University Graduate School of Medicine


Bibliographic Information

  • Book Title: Hormone Therapy and Castration Resistance of Prostate Cancer

  • Editors: Yoichi Arai, Osamu Ogawa

  • DOI: https://doi.org/10.1007/978-981-10-7013-6

  • Publisher: Springer Singapore

  • eBook Packages: Medicine, Medicine (R0)

  • Copyright Information: Springer Nature Singapore Pte Ltd. 2018

  • Hardcover ISBN: 978-981-10-7012-9Published: 28 May 2018

  • Softcover ISBN: 978-981-13-3906-6Published: 25 December 2018

  • eBook ISBN: 978-981-10-7013-6Published: 11 May 2018

  • Edition Number: 1

  • Number of Pages: VIII, 433

  • Number of Illustrations: 31 b/w illustrations, 34 illustrations in colour

  • Topics: Urology, Oncology

Buy it now

Buying options

eBook USD 89.00
Price excludes VAT (USA)
  • Available as EPUB and PDF
  • Read on any device
  • Instant download
  • Own it forever
Softcover Book USD 119.99
Price excludes VAT (USA)
  • Compact, lightweight edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info
Hardcover Book USD 169.99
Price excludes VAT (USA)
  • Durable hardcover edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info

Tax calculation will be finalised at checkout

Other ways to access