Overview
- Awarded as an Outstanding PhD thesis by the Chinese Academy of Sciences in 2015
- Describes a comprehensive study on using atomic force microscopy (AFM) to investigate single-cell and single-molecule activities
- Explores the biomedical applications of atomic force microscopy (AFM) in clinical practice for targeted cancer therapy
- Includes supplementary material: sn.pub/extras
Part of the book series: Springer Theses (Springer Theses)
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Table of contents (7 chapters)
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Front Matter
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Back Matter
Keywords
About this book
This book presents methodological and application research in detecting cellular and molecular biophysical properties based on atomic force microscopy (AFM) nanorobotics. Series methods for in situ label-free visualizing and quantifying the multiple physical properties of single cells and single molecules were developed, including immobilization strategies for observing fine structures of living cells, measurements of single-cell mechanics, force recognition of molecular interactions, and mapping protein organizations on cell surface. The biomedical applications of these methods in clinical lymphoma treatments were explored in detail, including primary sample preparation, cancer cell recognition, AFM detection and data analysis. Future directions about the biomedical applications of AFM are also given.
Authors and Affiliations
About the author
Bibliographic Information
Book Title: Investigations of Cellular and Molecular Biophysical Properties by Atomic Force Microscopy Nanorobotics
Authors: Mi Li
Series Title: Springer Theses
DOI: https://doi.org/10.1007/978-981-10-6829-4
Publisher: Springer Singapore
eBook Packages: Physics and Astronomy, Physics and Astronomy (R0)
Copyright Information: Springer Nature Singapore Pte Ltd. 2018
Hardcover ISBN: 978-981-10-6828-7Published: 17 October 2017
Softcover ISBN: 978-981-13-4954-6Published: 12 January 2019
eBook ISBN: 978-981-10-6829-4Published: 06 October 2017
Series ISSN: 2190-5053
Series E-ISSN: 2190-5061
Edition Number: 1
Number of Pages: XIII, 135
Number of Illustrations: 75 b/w illustrations
Topics: Nanoscale Science and Technology, Robotics and Automation, Biological and Medical Physics, Biophysics, Biological Microscopy, Spectroscopy and Microscopy, Immunology