Skip to main content
SpringerLink
Log in
Book cover

Synthesis of Functionalized Organoboron Compounds Through Copper(I) Catalysis

  • Book
  • © 2017

Overview

Authors:
  1. Koji Kubota

    1. Graduate School of Chemical Sciences and Engineering, Frontier Chemistry Center, Hokkaido University, Sapporo, Japan

    View author publications

    You can also search for this author in PubMed   Google Scholar

  • Nominated by Hokkaido University as an outstanding Ph.D. thesis
  • Focuses on the state-of-the-art of copper(I)-catalyzed borylation reaction
  • Provides details both of the reaction development and of theoretical study
  • Includes supplementary material: sn.pub/extras

Part of the book series: Springer Theses (Springer Theses)

This is a preview of subscription content, log in via an institution to check access.

Access this book

Log in via an institution
eBook USD 84.99
Price excludes VAT (USA)
  • Available as EPUB and PDF
  • Read on any device
  • Instant download
  • Own it forever
Softcover Book USD 109.99
Price excludes VAT (USA)
  • Compact, lightweight edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info
Hardcover Book USD 109.99
Price excludes VAT (USA)
  • Durable hardcover edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info

Tax calculation will be finalised at checkout

Other ways to access

Licence this eBook for your library

Institutional subscriptions

Table of contents (9 chapters)

  1. Front Matter

    Pages i-xiii
    Download chapter PDF

  2. General Introduction

    • Koji Kubota
    Pages 1-10

  3. Copper(I)-Catalyzed Direct Boryl Substitution of Unactivated Alkyl Halides

    • Koji Kubota
    Pages 11-26

  4. Copper(I)-Catalyzed Intermolecular Borylative Exo-cyclization of Alkenyl Halides Containing Unactivated Double Bond

    • Koji Kubota
    Pages 27-70

  5. Copper(I)-Catalyzed Regio- and Enantioselective Monoborylation of Alkenylsilanes

    • Koji Kubota
    Pages 71-98

  6. Copper(I)-Catalyzed Enantioselective Nucleophilic Borylation of Aldehydes

    • Koji Kubota
    Pages 99-127

  7. Computational Insight into the Enantioselective Borylation of Aldehydes Catalyzed by Chiral Bisphosphine Copper(I) Complexes

    • Koji Kubota
    Pages 129-146

  8. Copper(I)-Catalyzed Enantioselective Borylative Dearomatization of Indoles

    • Koji Kubota
    Pages 147-177

  9. Copper(I)-Catalyzed Regio- and Enantioselective Borylation of 1,2-Dihydropyridines

    • Koji Kubota
    Pages 179-207

  10. Summary and Outlook

    • Koji Kubota
    Pages 209-210

  11. Back Matter

    Pages 211-213
    Download chapter PDF
Back to top

Keywords

About this book

This book describes state-of-the-art borylation chemistry using copper(I) catalysis. Enantioselective reactions are included to afford a variety of functionalized, complex organoboronate esters, which will find wide application in asymmetric synthesis, drug discovery, and material science. Organoboron compounds are recognized as useful reagents in organic synthesis; therefore, great effort has been devoted to the development of a simple, mild, and efficient method for their preparation in the past several years. However, the synthesis of functionalized organoboron compounds remains a challenging issue because known reactions often require the use of highly reactive organometallic carbon nucleophiles. This book focuses on conceptually new, formal nucleophilic copper(I)-catalyzed borylation reactions with diboron compounds that show high selectivity and excellent functional group compatibility. Theoretical studies based on density functional theory calculations to understand the reactionmechanisms have also been described. Advances in this novel borylation chemistry will allow the rapid and efficient synthesis of complex molecules with potentially interesting properties in combination with the boron functionalization process. 

Authors and Affiliations

  • Graduate School of Chemical Sciences and Engineering, Frontier Chemistry Center, Hokkaido University, Sapporo, Japan

    Koji Kubota

Bibliographic Information

  • Book Title: Synthesis of Functionalized Organoboron Compounds Through Copper(I) Catalysis

  • Authors: Koji Kubota

  • Series Title: Springer Theses

  • DOI: https://doi.org/10.1007/978-981-10-4935-4

  • Publisher: Springer Singapore

  • eBook Packages: Chemistry and Materials Science, Chemistry and Material Science (R0)

  • Copyright Information: Springer Nature Singapore Pte Ltd. 2017

  • Hardcover ISBN: 978-981-10-4934-7Published: 07 July 2017

  • Softcover ISBN: 978-981-13-5271-3Published: 12 December 2018

  • eBook ISBN: 978-981-10-4935-4Published: 27 June 2017

  • Series ISSN: 2190-5053

  • Series E-ISSN: 2190-5061

  • Edition Number: 1

  • Number of Pages: XIII, 213

  • Number of Illustrations: 225 b/w illustrations

  • Topics: Organic Chemistry, Catalysis

Publish with us

Policies and ethics

Back to top

Search

Navigation