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  • © 2017

Exosomes in Cardiovascular Diseases

Biomarkers, Pathological and Therapeutic Effects

  • Provides the first intensive overview on exosomes in cardiovascular diseases
  • Covers future prospects of the research
  • Contributed by leading experts in the field

Part of the book series: Advances in Experimental Medicine and Biology (AEMB, volume 998)

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Table of contents (19 chapters)

  1. Front Matter

    Pages i-vii
  2. Overview

    1. Front Matter

      Pages 1-1
    2. The Multifaceted Functions of Exosomes in Health and Disease: An Overview

      • Claudia Arenaccio, Maurizio Federico
      Pages 3-19
  3. Basic Aspects of Exosomes

    1. Front Matter

      Pages 21-21
    2. Exosomes: Nanocarriers of Biological Messages

      • Alice Conigliaro, Simona Fontana, Stefania Raimondo, Riccardo Alessandro
      Pages 23-43
    3. Functional Role of Cardiovascular Exosomes in Myocardial Injury and Atherosclerosis

      • Maarten Vanhaverbeke, Diane Gal, Paul Holvoet
      Pages 45-58
  4. Exosomes as Biomarkers of Cardiovascular Diseases

    1. Front Matter

      Pages 59-59
    2. Exosomes-Based Biomarkers for the Prognosis of Cardiovascular Diseases

      • Yihua Bei, Pujiao Yu, Dragos Cretoiu, Sanda Maria Cretoiu, Junjie Xiao
      Pages 71-88
  5. Pathological Effects of Exosomes

    1. Front Matter

      Pages 89-89
    2. Dual Behavior of Exosomes in Septic Cardiomyopathy

      • Valter Vinícius Silva Monteiro, Jordano Ferreira Reis, Rafaelli de Souza Gomes, Kely Campos Navegantes, Marta Chagas Monteiro
      Pages 101-112
    3. Pathological Effects of Exosomes in Mediating Diabetic Cardiomyopathy

      • Esam S. B. Salem, Guo-Chang Fan
      Pages 113-138
    4. Peripartum Cardiomyopathy: Do Exosomes Play a Role?

      • Huanyu Gu, Qiying Dai, Zhuyuan Liu, Hongbao Wang, Jianhua Yao, Lei Zhou
      Pages 139-149
    5. Vascular Calcification Regulation by Exosomes in the Vascular Wall

      • Marcel Liberman, Luciana Cavalheiro Marti
      Pages 151-160
  6. Therapeutic Effects of Exosomes

    1. Front Matter

      Pages 161-161
    2. Cardioprotective Effects of Exosomes and Their Potential Therapeutic Use

      • Shengguang Ding, Jingying Zhang, Qiying Dai, Mengfei Zhao, Haitao Huang, Yiming Xu et al.
      Pages 163-177
    3. Therapeutic Effects of Mesenchymal Stem Cell-Derived Exosomes in Cardiovascular Disease

      • Etsu Suzuki, Daishi Fujita, Masao Takahashi, Shigeyoshi Oba, Hiroaki Nishimatsu
      Pages 179-185
    4. Exosomes Derived from Embryonic Stem Cells as Potential Treatment for Cardiovascular Diseases

      • Yao-Hua Song, Lianbo Shao, Yu Zhang, Jin Zhou, Bin Liu, Xiangbin Pan et al.
      Pages 187-206
    5. Cardiac Progenitor-Cell Derived Exosomes as Cell-Free Therapeutic for Cardiac Repair

      • E. A. Mol, M. J. Goumans, J. P. G. Sluijter
      Pages 207-219

About this book

The book provides and intensive overview on exosomes in cardiovascular diseases, its potential as biomarkers, as well as pathological and therapeutic effects. It firstly describes the general aspects of exosomes including the definition, formation and secretion of exosomes and highlight their roles as biomarkers and pathological and therapeutic effects in cardiovascular diseases as well. Secondly, basic aspects of exosomes including the purification methods of exosomes, exosomes content, and functional roles of the cardiovascular exosomes are summarized. Thirdly, exosomes as biomarkers of cardiovascular diseases are overviewed including their roles in diagnosis, prognosis and reaction to therapy. Fourthly, pathological effects of exosomes and therapeutic effects of exosomes are highlighted. Finally, future prospects of exosomes in cardiovascular research would be provided. This is an essential reference for researchers working in cell biology and regeneration, as well as clinicianssuch as cardiologist.

Editors and Affiliations

  • Shanghai University , Shanghai, China

    Junjie Xiao

  • Victor Babeş National Institute of Patho , Bucharest, Romania

    Sanda Cretoiu

About the editors

Dr. Junjie Xiao is Principal Investigator and Associate Professor at Cardiac Regeneration and Ageing Lab in Shanghai University, Shanghai, China;

Dr. Sanda Cretoiu is an Associate Professor at Victor Babeş National Institute of Pathology, 'Carol Davila' University of Medicine and Pharmacy, Bucharest, Romania.

Bibliographic Information

  • Book Title: Exosomes in Cardiovascular Diseases

  • Book Subtitle: Biomarkers, Pathological and Therapeutic Effects

  • Editors: Junjie Xiao, Sanda Cretoiu

  • Series Title: Advances in Experimental Medicine and Biology

  • DOI: https://doi.org/10.1007/978-981-10-4397-0

  • Publisher: Springer Singapore

  • eBook Packages: Biomedical and Life Sciences, Biomedical and Life Sciences (R0)

  • Copyright Information: The Editor(s) (if applicable) and The Author(s), under exclusive license to Springer Nature Singapore Pte Ltd. 2017

  • Hardcover ISBN: 978-981-10-4396-3Published: 05 October 2017

  • Softcover ISBN: 978-981-13-5127-3Published: 12 December 2018

  • eBook ISBN: 978-981-10-4397-0Published: 19 September 2017

  • Series ISSN: 0065-2598

  • Series E-ISSN: 2214-8019

  • Edition Number: 1

  • Number of Pages: VII, 307

  • Number of Illustrations: 2 b/w illustrations, 30 illustrations in colour

  • Topics: Molecular Medicine, Human Physiology, Cardiology

Buy it now

Buying options

eBook USD 89.00
Price excludes VAT (USA)
  • Available as EPUB and PDF
  • Read on any device
  • Instant download
  • Own it forever
Softcover Book USD 119.99
Price excludes VAT (USA)
  • Compact, lightweight edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info
Hardcover Book USD 169.99
Price excludes VAT (USA)
  • Durable hardcover edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info

Tax calculation will be finalised at checkout

Other ways to access