Overview
- Provides a comprehensive knowledge of long and short ncRNAs
- Chapters highlight recent advances in specific topics, like the molecular mechanisms of various classes of ncRNAs in cancer
- Contributed by experts in this field
Part of the book series: Advances in Experimental Medicine and Biology (AEMB, volume 927)
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Table of contents (16 chapters)
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Front Matter
Keywords
About this book
The book conveys a comprehensive knowledge of long and short ncRNAs in cancer regulation and their potentials as diagnostic biomarkers and therapeutic targets. Topics covered include the molecular mechanisms of various classes of ncRNAs (with emphasis on long non-coding RNAs and microRNAs) in cancer, the functional roles of ncRNAs in regulating different cancer hallmarks (including proliferation, apoptosis, stem-cell properties, epithelial-mesenchymal transition, metabolism, angiogenesis, tumor-host interactions and therapeutic resistance), the role of ncRNAs in regulating cancer signaling circuitry programs (highlighting their involvement in c-myc, p53 and NFkB signaling), a systemic summary of clinical and preclinical studies that evaluate the potential of ncRNA signatures for cancer diagnosis and prognosis and strategies to delivery short ncRNAs as therapeutic molecules for cancer treatment. This book may serve as a comprehensive resource for researchers, graduate students and oncologists in ncRNA and cancer research and help drug development by identifying ncRNA targets.
Editors and Affiliations
About the editor
Bibliographic Information
Book Title: The Long and Short Non-coding RNAs in Cancer Biology
Editors: Erwei Song
Series Title: Advances in Experimental Medicine and Biology
DOI: https://doi.org/10.1007/978-981-10-1498-7
Publisher: Springer Singapore
eBook Packages: Biomedical and Life Sciences, Biomedical and Life Sciences (R0)
Copyright Information: The Editor(s) (if applicable) and The Author(s), under exclusive license to Springer Nature Singapore Pte Ltd. 2016
Hardcover ISBN: 978-981-10-1496-3Published: 12 July 2016
Softcover ISBN: 978-981-10-9367-8Published: 07 June 2018
eBook ISBN: 978-981-10-1498-7Published: 04 July 2016
Series ISSN: 0065-2598
Series E-ISSN: 2214-8019
Edition Number: 1
Number of Pages: VIII, 458
Number of Illustrations: 21 b/w illustrations
Topics: Cancer Research, Cell Biology