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Fundamentals of Enzyme Engineering

  • Book
  • © 2017

Overview

  • Focuses on the biosynthesis of enzymes such as the mutagenesis and expression of protein in a microorganism
  • Provides useful insights on aspects of enzyme biosynthesis and production as well as their direct industrial application
  • Describes methods to enhance enzyme stability and catalytic power, enzymes used in non-conventional media and their applications
  • Includes supplementary material: sn.pub/extras

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Table of contents (15 chapters)

  1. Introduction to Enzyme Engineering

  2. Enzyme Reaction Engineering

  3. Molecular Understanding of Enzymes

  4. Applications of Enzymes

Keywords

About this book

This book provides a comprehensive introduction to all aspects of enzyme engineering, from fundamental principles through to the state-of-the-art in research and industrial applications.

It begins with a brief history, describing the milestones of advancement in enzyme science and technology, before going on to cover the fundamentals of enzyme chemistry, the biosynthesis of enzymes and their production. Enzyme stability and the reaction kinetics during enzymatic reactions are presented to show how enzymes function during catalysis and the factors that affect their activity. Methods to improve enzyme performance are also presented, such as cofactor regeneration and enzyme immobilization. The book emphasizes and elaborates on the performance and characteristics of enzymes at the molecular level. Finally, the book presents recent advances in enzyme engineering and some key industrial application of enzymes addressing the present needs of society.

This book presents essential information not only for undergraduate and graduate students, but also for researchers in academia and industry, providing a valuable reference for the development of commercial applications of enzyme technology.

Authors and Affiliations

  • School of Chemical and Biological Engineering, Seoul National University, Seoul, Korea (Republic of)

    Young Je Yoo

  • College of Life Science and Biotechnology, Shanghai JiaoTong University, Shanghai, China

    Yan Feng

  • School of Energy and Chemical Engineering, Ulsan National Institute of Science and Technology, Ulsan, Korea (Republic of)

    Yong-Hwan Kim

  • School of Chemical Engineering, University of San Carlos, Cebu City, Philippines

    Camila Flor J. Yagonia

About the authors

Prof. Yoo, Young Je is currently a Professor at the School of Chemical Engineering, Seoul National University and holds a B.S. from Department of Chemical Engineering, Seoul National University and a Ph.D. at the Department of Chemical Engineering, University of Maryland. His research interests are understanding of enzyme’s function at the molecular level and engineering and design of enzyme activity, stability and specificity, and enzymatic reactions for useful chemicals production and environmental applications.

Prof. Feng, Yan is currently a Professor at the School of Life Sciences and Biotechnology, Shanghai Jiao Tong University, China and holds B.S. from Department of Molecular Biology, Jilin University, M.S.from State Key Laboratory of Enzyme Engineering,and M.D. from Basic Medical Sciences School, Bethune Medical University. Her research interests focus on investigating the enzyme structure-function relationship, as well as employing rational design and direct evolution to engineer useful biocatalysts.

Prof. Kim, Yong Hwan is currently a Professor at the School of Energy and Chemical Engineering, Ulsan National Institute of Science and Technology and holds a B.S., M.S., and Ph.D. from Department of Chemical Engineering, Seoul National University. He is actively developing new biocatalysts for the conversion of C1 gas compounds to value-added chemicals based on the profound experience in industry and national research institutes. He has been involved in the commercialisation of enzyme-catalyzed polymerization of phenolics for special coating materials and enzyme-catalyzed production of linin based material for automotive industry.

Prof. Yagonia, Camila Flor J. is currently a professor at the Department of Chemical Engineering, San Carlos University, Philippines. She got BS and Ms degrees from San Carlos University and PhD from Seoul National University. Her research interests include bioenergy production, production of chemicals and materials using biotechnology, and industrial applications of enzymes.

Bibliographic Information

  • Book Title: Fundamentals of Enzyme Engineering

  • Authors: Young Je Yoo, Yan Feng, Yong-Hwan Kim, Camila Flor J. Yagonia

  • DOI: https://doi.org/10.1007/978-94-024-1026-6

  • Publisher: Springer Dordrecht

  • eBook Packages: Chemistry and Materials Science, Chemistry and Material Science (R0)

  • Copyright Information: Springer Science+Business Media B.V. 2017

  • Hardcover ISBN: 978-94-024-1024-2Published: 23 January 2017

  • Softcover ISBN: 978-94-024-1469-1Published: 13 July 2018

  • eBook ISBN: 978-94-024-1026-6Published: 12 January 2017

  • Edition Number: 1

  • Number of Pages: X, 209

  • Number of Illustrations: 84 b/w illustrations, 11 illustrations in colour

  • Topics: Biochemical Engineering, Protein Science, Bioorganic Chemistry

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