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The Biochemistry of Retinoid Signaling II

The Physiology of Vitamin A - Uptake, Transport, Metabolism and Signaling

  • Provides a history of vitamin A research from earliest knowledge to the present
  • Provides up-to-date descriptions of all aspects of vitamin A uptake, transport and utilization in mammalian systems
  • Provides an overview of vitamin A related molecules and processes that have recently been shown to be present in non-mammalian and invertebrate systems
  • Provides an overview of the role of vitamin A in vision

Part of the book series: Subcellular Biochemistry (SCBI, volume 81)

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Table of contents (9 chapters)

  1. Front Matter

    Pages i-ix
  2. Carotenoids and Retinoids: Nomenclature, Chemistry, and Analysis

    • Earl H. Harrison, Robert W. Curley Jr.
    Pages 1-19
  3. Vitamin A Absorption, Storage and Mobilization

    • William S. Blaner, Yang Li, Pierre-Jacques Brun, Jason J. Yuen, Seung-Ah Lee, Robin D. Clugston
    Pages 95-125
  4. Retinoic Acid Synthesis and Degradation

    • Natalia Y. Kedishvili
    Pages 127-161
  5. Vitamin A and Vision

    • John C. Saari
    Pages 231-259
  6. Back Matter

    Pages 261-263

About this book

The role of vitamin A in living organisms has been known throughout human history. In the last 100 years, the biochemical nature of vitamin A and its active derivative, retinoic acid, its physiological impact on growth processes, and the essential details of its mechanism of action have been revealed by investigations carried out by researchers using vertebrate and more recently invertebrate models to study a multiplicity of processes and conditions, encompassing embryogenesis, postnatal development to old age. A wealth of intercellular interactions, intracellular signaling systems, and molecular mechanisms have been described and the overall conclusion is that retinoic acid is essential for life.  This book series, with chapters authored by experts in every aspect of this complex field, unifies the knowledge base and mechanisms currently known in detailed, engaging, well-illustrated, focused chapters that synthesize information for each specific area.

In view of the recent information explosion in this field, it is timely to publish a contemporary, comprehensive, book series recapitulating the most exciting developments in the field and covering fundamental research in molecular mechanisms of vitamin A action, its role in physiology, development, and continued well-being, and the potential of vitamin A derivatives and synthetic mimetics to serve as therapeutic treatments for cancers and other debilitating human diseases.   


Volume II is divided into nine chapters contributed by prominent experts in their respective fields. Each chapter starts with the history of the area of research. Then, the key findings that contributed to development of the field are described, followed by a detailed look at key findings and progress that are being made in current, ongoing research. Each chapter is concluded with a discussion of the relevance of the research and a perspective on missing pieces and lingering gaps that the author recommends will be important in defining future directions in vitamin A research.



Editors and Affiliations

  • Tennessee State University, Nashville, USA

    Mary Ann Asson-Batres

  • Functional Genomics & Cancer, Institut de Genetique et de Department Functional Genomics & Cancer, Illkirch, France

    Cecile Rochette-Egly

Bibliographic Information

  • Book Title: The Biochemistry of Retinoid Signaling II

  • Book Subtitle: The Physiology of Vitamin A - Uptake, Transport, Metabolism and Signaling

  • Editors: Mary Ann Asson-Batres, Cecile Rochette-Egly

  • Series Title: Subcellular Biochemistry

  • DOI: https://doi.org/10.1007/978-94-024-0945-1

  • Publisher: Springer Dordrecht

  • eBook Packages: Biomedical and Life Sciences, Biomedical and Life Sciences (R0)

  • Copyright Information: Springer Science+Business Media Dordrecht 2016

  • Hardcover ISBN: 978-94-024-0943-7Published: 17 November 2016

  • Softcover ISBN: 978-94-024-1444-8Published: 24 April 2018

  • eBook ISBN: 978-94-024-0945-1Published: 09 November 2016

  • Series ISSN: 0306-0225

  • Series E-ISSN: 2542-8810

  • Edition Number: 1

  • Number of Pages: IX, 263

  • Number of Illustrations: 12 b/w illustrations, 41 illustrations in colour

  • Topics: Gene Expression, Animal Biochemistry, Protein Science, Nutrition, Plant Biochemistry, Systems Biology

Buy it now

Buying options

eBook USD 189.00
Price excludes VAT (USA)
  • Available as EPUB and PDF
  • Read on any device
  • Instant download
  • Own it forever
Softcover Book USD 249.99
Price excludes VAT (USA)
  • Compact, lightweight edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info
Hardcover Book USD 249.99
Price excludes VAT (USA)
  • Durable hardcover edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info

Tax calculation will be finalised at checkout

Other ways to access