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Cancer Drug Discovery

Science and History

  • Book
  • © 2016

Overview

Authors:
  1. Kyu-Won Kim

    1. College of Pharmacy, Seoul National University, Seoul, Korea (Republic of)

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  2. Jae Kyung Roh

    1. Department of Internal Medicine, Yonsei University College of Medicine, Seoul, Korea (Republic of)

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  3. Hee-Jun Wee

    1. College of Pharmacy, Seoul National University, Seoul, Korea (Republic of)

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  4. Chan Kim

    1. Department of Internal Medicine, CHA Bundang Medical Center, Seongnam, Korea (Republic of)

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  • Presents comprehensive charts of important discoveries of scientific endeavours on cancer research
  • Includes timelines and conceptual cartoons for wide spectrum of anticancer drugs
  • Provides a novel perspective for the research on cell network according to the systemic view of cancer

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Table of contents (11 chapters)

  1. Front Matter

    Pages i-xvii
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  2. A Scientific Overview on Cancer

    1. Front Matter

      Pages 1-1
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    2. Advancements in Life Sciences and Characteristic Features of Cancer Cells

      • Kyu-Won Kim, Jae Kyung Roh, Hee-Jun Wee, Chan Kim
      Pages 3-23

    3. Advancement of the Science and History of Cancer and Anticancer Drugs

      • Kyu-Won Kim, Jae Kyung Roh, Hee-Jun Wee, Chan Kim
      Pages 25-56

  3. Cancer Drug Discovery: Types and History

    1. Front Matter

      Pages 57-57
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    2. Chronology of Anticancer Drug Development

      • Kyu-Won Kim, Jae Kyung Roh, Hee-Jun Wee, Chan Kim
      Pages 59-70

    3. Alkylating Anticancer Drugs

      • Kyu-Won Kim, Jae Kyung Roh, Hee-Jun Wee, Chan Kim
      Pages 71-94

    4. Antimetabolic Anticancer Drugs

      • Kyu-Won Kim, Jae Kyung Roh, Hee-Jun Wee, Chan Kim
      Pages 95-112

    5. Natural Product Anticancer Drugs

      • Kyu-Won Kim, Jae Kyung Roh, Hee-Jun Wee, Chan Kim
      Pages 113-134

    6. Immunotherapeutic Anticancer Drugs and Other Miscellaneous Anticancer Drugs

      • Kyu-Won Kim, Jae Kyung Roh, Hee-Jun Wee, Chan Kim
      Pages 135-153

    7. Hormonal Anticancer Drugs

      • Kyu-Won Kim, Jae Kyung Roh, Hee-Jun Wee, Chan Kim
      Pages 155-174

    8. Molecular Targeted Anticancer Drugs

      • Kyu-Won Kim, Jae Kyung Roh, Hee-Jun Wee, Chan Kim
      Pages 175-238

    9. Complications of Anticancer Drugs and Their Management

      • Kyu-Won Kim, Jae Kyung Roh, Hee-Jun Wee, Chan Kim
      Pages 239-256

  4. A Paradigm Shift in Cancer Research

    1. Front Matter

      Pages 257-257
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    2. Advancements in Bioscience and New Cancer Drugs

      • Kyu-Won Kim, Jae Kyung Roh, Hee-Jun Wee, Chan Kim
      Pages 259-276
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Keywords

About this book

The reader will discover a comprehensive and multifaceted overview of the history of the development of anticancer drugs deeply influenced by the cell concept of cancer and future directions for the development of new anticancer drugs. First, this book documents the scientific progress in biological science over the last 70 years and the influence this progress had in cancer research. Summaries and charts of important discoveries complete this overview. Furthermore, this book outlines the process of anticancer drug development with a focus on the characteristic drug groups of each era, related to advancements of chemistry and biological sciences. This book also provides brief mechanism of action of drugs, illustrated by comprehensive timelines and conceptual cartoons. This book finally sums up the limitations of the current anticancer drug development and seeks new directions for anticancer drug discovery, considering under the systemic view of cancer.

Authors and Affiliations

  • College of Pharmacy, Seoul National University, Seoul, Korea (Republic of)

    Kyu-Won Kim, Hee-Jun Wee

  • Department of Internal Medicine, Yonsei University College of Medicine, Seoul, Korea (Republic of)

    Jae Kyung Roh

  • Department of Internal Medicine, CHA Bundang Medical Center, Seongnam, Korea (Republic of)

    Chan Kim

About the authors

Dr. Kyu-Won Kim College of Pharmacy, Seoul National University, Seoul, South Korea
Dr. Jae Kyung Roh Yonsei Cancer Center, Yonsei University College of Medicine, Seoul, South Korea
Dr. Hee-Jun Wee College of Pharmacy, Seoul National University, Seoul, South KoreaDr. Chan Kim CHA Bundang Medical Center, CHA University, Seongnam-si, South Korea




Bibliographic Information

  • Book Title: Cancer Drug Discovery

  • Book Subtitle: Science and History

  • Authors: Kyu-Won Kim, Jae Kyung Roh, Hee-Jun Wee, Chan Kim

  • DOI: https://doi.org/10.1007/978-94-024-0844-7

  • Publisher: Springer Dordrecht

  • eBook Packages: Biomedical and Life Sciences, Biomedical and Life Sciences (R0)

  • Copyright Information: Springer Science+Business Media Dordrecht 2016

  • Hardcover ISBN: 978-94-024-0842-3Published: 23 November 2016

  • Softcover ISBN: 978-94-024-1417-2Published: 05 July 2018

  • eBook ISBN: 978-94-024-0844-7Published: 14 November 2016

  • Edition Number: 1

  • Number of Pages: XVII, 276

  • Number of Illustrations: 4 b/w illustrations, 134 illustrations in colour

  • Additional Information: Originally published by PanMun Education Co., Seoul, 2015

  • Topics: Cancer Research, Pharmacy, History of Medicine

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