Overview
- In depth discussion of the state of the art of systems immunology
- Presents revealing in-depth information on individual subgroups of lymphocytes
- Features up-to-date research
Part of the book series: Translational Bioinformatics (TRBIO, volume 5)
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Table of contents (13 chapters)
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Front Matter
Keywords
About this book
The volume focuses on the genomics, proteomics, metabolomics, and bioinformatics of a single cell, especially lymphocytes and on understanding the molecular mechanisms of systems immunology. Based on the author’s personal experience, it provides revealing insights into the potential applications, significance, workflow, comparison, future perspectives and challenges of single-cell sequencing for identifying and developing disease-specific biomarkers in order to understand the biological function, activation and dysfunction of single cells and lymphocytes and to explore their functional roles and responses to therapies. It also provides detailed information on individual subgroups of lymphocytes, including cell characters, function, surface markers, receptor function, intracellular signals and pathways, production of inflammatory mediators, nuclear receptors and factors, omics, sequencing, disease-specific biomarkers, bioinformatics, networks and dynamic networks, their role in disease and future prospects.
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Dr. Xiangdong Wang is a Professor of Medicine, Director of Shanghai Institute of Clinical Bioinformatics, Director of Fudan University Center for Clinical Bioinformatics, Director of the Biomedical Research Center of Zhongshan Hospital, Deputy Director of Shanghai Respiratory Research Institute, Shanghai, China.
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Editors and Affiliations
Bibliographic Information
Book Title: Single Cell Sequencing and Systems Immunology
Editors: Xiangdong Wang
Series Title: Translational Bioinformatics
DOI: https://doi.org/10.1007/978-94-017-9753-5
Publisher: Springer Dordrecht
eBook Packages: Biomedical and Life Sciences, Biomedical and Life Sciences (R0)
Copyright Information: Springer Science+Business Media Dordrecht 2015
Hardcover ISBN: 978-94-017-9752-8Published: 14 April 2015
Softcover ISBN: 978-94-024-0064-9Published: 09 October 2016
eBook ISBN: 978-94-017-9753-5Published: 27 March 2015
Series ISSN: 2213-2775
Series E-ISSN: 2213-2783
Edition Number: 1
Number of Pages: XI, 177
Number of Illustrations: 27 b/w illustrations, 62 illustrations in colour
Topics: Immunology, Systems Biology, Proteomics, Cell Biology