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Epigenetics Territory and Cancer

  • Book
  • © 2015

Overview

Editors:
  1. Parvin Mehdipour

    1. Tehran University of Medical Sciences, Department of Medical Genetics School Of Medicine, Tehran, Iran

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  • Presents original research data in figures that illustrate new insights in cancer epigenetics
  • Collates fundamentals of epigenetics, the latest research and therapeutic design in treatment of cancer
  • Explores links between cancer research, medicine, and anthropology
  • Includes supplementary material: sn.pub/extras

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Table of contents (17 chapters)

  1. Front Matter

    Pages i-xii
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  2. Fundamental Aspects of Epigenetic in Cancer

    • Thomas Eggermann, Ulrike Gamerdinger, Gesa Schwanitz
    Pages 1-33

  3. Biodynamic Phenotypic and Epigenetics Changes of Circulating Tumor Cells: Their Application in Cancer Prognosis and Treatment

    • Ma José Serrano Fernández, Ma Jesús Alvarez-Cubero, Jose Luis García Puche, F Gabriel Ortega, Jose Antonio Lorente
    Pages 35-49

  4. LINE-1 Retrotransposons and Their Role in Cancer

    • Raheleh Rahbari, Laleh Habibi, Jose L. Garcia-Puche, Richard M. Badge, Jose Garcia-Perez
    Pages 51-99

  5. Reciprocal Interconnection of miRNome-Epigenome in Cancer Pathogenesis and Its Therapeutic Potential

    • Seyed H. Ghaffari, Davood Bashash
    Pages 101-135

  6. Reduced Risk of Cancer in Schizophrenia, a Bridge Toward Etio-Pathology and Therapy of Both Diseases

    • Mohamad Reza Eskandari, Hamid Mostafavi Abdolmaleky, Jin-Rong Zhou, Sam Thiagalingam
    Pages 137-166

  7. Exploring ATM and Methylation in Cancer: Emphasizing on Brain Tumors

    • Parvin Mehdipour, Fatemeh Karami
    Pages 167-201

  8. Molecular and Biological Aspects of Microcephalin Gene: Directions in Brain Tumor and Methylation

    • Fatemeh Karami, Parvin Mehdipour
    Pages 203-219

  9. Sentinel Gene Within Cell Territory and Molecular Platforms in Cancer: Methylation Diversity of p53 Gene in Brain Tumors

    • Parvin Mehdipour, Fatemeh Karami
    Pages 221-250

  10. Predictive Role of O6-Methylguanine DNA Methyltransferase Status for the Treatment of Brain Tumors

    • Marina V. Matsko, Evgeny N. Imaynitov
    Pages 251-279

  11. Epigenetics and Three Main Clinical Aspects of Breast Cancer Management

    • Pantea Izadi, Mehrdad Noruzinia
    Pages 281-309

  12. Epigenetic of Retinoic Acid Receptor β2 Gene in Breast Cancer

    • Parvin Mehdipour
    Pages 311-362

  13. Retinoic Acid Receptor-β, From Gene to Clinic

    • Hassan Fazilaty, Parvin Mehdipour
    Pages 363-372

  14. Methylation in Colorectal Cancer

    • Pooneh Mokarram, Mehrdad Asghari Estiar, Hassan Ashktorab
    Pages 373-455

  15. Malignant Rhabdoid Tumor: Epigenetic Mechanism of Tumorogenesis

    • Sima Kheradmand Kia
    Pages 457-478

  16. Epigenetics of Thyroid Cancer

    • Javad Mohammadi-Asl
    Pages 479-493

  17. An Introduction to Impact of Bio-Resonance Technology in Genetics and Epigenetics

    • Mohammad Ebrahimi, Sabokhi Sharifov, Maryam Salili, Larysia Chernosova
    Pages 495-513

  18. Essence of Cancer Epigenetic: A Harmonic Art for the Future

    • Parvin Mehdipour
    Pages 515-526

  19. Back Matter

    Pages 527-539
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Keywords

About this book

This book explores epigenetic strategies, bridging fundamental cancer epigenetics, different paradigms in tumor genetics and translational understanding for both the clinic and improved lifestyles. The work provides target-based insights for treating different types of cancers and presents research on evolutionary epigenetics, introducing ‘Medical Epi- Anthropology’ and ‘Cancer Epi-Anthropology’. Translating multi-disciplinary research into therapeutic design is at the core of this book. Readers may explore how cancer management involves unmasking the involved networks and the interactive status of different genes to achieve the appropriate methylome based therapy. Early chapters explore fundamental aspects and brain tumours, whilst later chapters investigate breast cancer and various other cancers, and the final chapter presents an evolutionary insight in cancer epigenetics, considering that the epigene is beyond DNA methylation, RNA interference and histone modification in cancer development. This book will be of interest to researchers in different medical and scientific fields, including clinical management (diagnosis, prognosis, prediction, prevention, and guidelines), genetic education, nutrition and nutrigenomics, industrial chemistry, and drug innovation. Because of the unique bridging between science and medicine this book will also be useful as an educational and translational research package.

Editors and Affiliations

  • Tehran University of Medical Sciences, Department of Medical Genetics School Of Medicine, Tehran, Iran

    Parvin Mehdipour

Bibliographic Information

  • Book Title: Epigenetics Territory and Cancer

  • Editors: Parvin Mehdipour

  • DOI: https://doi.org/10.1007/978-94-017-9639-2

  • Publisher: Springer Dordrecht

  • eBook Packages: Biomedical and Life Sciences, Biomedical and Life Sciences (R0)

  • Copyright Information: Springer Science+Business Media Dordrecht 2015

  • Hardcover ISBN: 978-94-017-9638-5Published: 31 March 2015

  • Softcover ISBN: 978-94-024-0816-4Published: 09 October 2016

  • eBook ISBN: 978-94-017-9639-2Published: 18 March 2015

  • Edition Number: 1

  • Number of Pages: XII, 539

  • Number of Illustrations: 43 b/w illustrations, 53 illustrations in colour

  • Topics: Cancer Research, Cell Biology, Oncology, Biomedicine general

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