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Biodemography of Aging

Determinants of Healthy Life Span and Longevity

  • Presents an innovative overview of the field of biodemography of aging
  • Provides rigorous research into how age-related changes at individual level contribute to morbidity
  • First volume covering the work done by the leading research team at the Center for Population Health and Aging at Duke

Part of the book series: The Springer Series on Demographic Methods and Population Analysis (PSDE, volume 40)

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Table of contents (20 chapters)

  1. Front Matter

    Pages i-xvii
  2. Introduction: The Biodemography of Complex Relationships Among Aging, Health, and Longevity

    • Anatoliy I. Yashin, Eric Stallard, Kenneth C. Land
    Pages 1-18
  3. Information on Aging, Health, and Longevity from Available Data

    1. Front Matter

      Pages 19-19
    2. Age Trajectories of Physiological Indices: Which Factors Influence Them?

      • Anatoliy I. Yashin, Liubov S. Arbeeva, Konstantin G. Arbeev, Igor Akushevich, Alexander M. Kulminski, Eric Stallard et al.
      Pages 21-45
    3. Health Effects and Medicare Trajectories: Population-Based Analysis of Morbidity and Mortality Patterns

      • Igor Akushevich, Julia Kravchenko, Konstantin G. Arbeev, Svetlana V. Ukraintseva, Kenneth C. Land, Anatoliy I. Yashin
      Pages 47-93
    4. Evidence for Dependence Among Diseases

      • Anatoliy I. Yashin, Svetlana V. Ukraintseva, Igor Akushevich, Alexander M. Kulminski, Konstantin G. Arbeev, Eric Stallard
      Pages 95-111
    5. Factors That May Increase Vulnerability to Cancer and Longevity in Modern Human Populations

      • Svetlana V. Ukraintseva, Konstantin G. Arbeev, Igor Akushevich, Alexander M. Kulminski, Eric Stallard, Anatoliy I. Yashin
      Pages 113-141
    6. Medical Cost Trajectories and Onset of Age-Associated Diseases

      • Igor Akushevich, Julia Kravchenko, Konstantin G. Arbeev, Svetlana V. Ukraintseva, Kenneth C. Land, Anatoliy I. Yashin
      Pages 143-162
    7. Indices of Cumulative Deficits

      • Alexander M. Kulminski, Kenneth C. Land, Anatoliy I. Yashin
      Pages 163-186
    8. Dynamic Characteristics of Aging-Related Changes as Predictors of Longevity and Healthy Lifespan

      • Anatoliy I. Yashin, Konstantin G. Arbeev, Svetlana V. Ukraintseva, Liubov S. Arbeeva, Igor Akushevich, Julia Kravchenko et al.
      Pages 187-210
    9. The Complex Role of Genes in Diseases and Traits in Late Life: An Example of the Apolipoprotein E Polymorphism

      • Alexander M. Kulminski, Anatoliy I. Yashin, Irina Culminskaya, Kenneth C. Land, Svetlana V. Ukraintseva
      Pages 211-230
    10. Conclusions Regarding Empirical Patterns of Aging, Health, and Longevity

      • Alexander M. Kulminski, Anatoliy I. Yashin, Irina Culminskaya, Kenneth C. Land, Svetlana V. Ukraintseva
      Pages 231-237
  4. Statistical Modeling of Aging, Health, and Longevity

    1. Front Matter

      Pages 239-239
    2. Approaches to Statistical Analysis of Longitudinal Data on Aging, Health, and Longevity: Biodemographic Perspectives

      • Konstantin G. Arbeev, Igor Akushevich, Alexander M. Kulminski, Kenneth C. Land, Anatoliy I. Yashin
      Pages 241-261
    3. Stochastic Process Models of Mortality and Aging

      • Anatoliy I. Yashin, Konstantin G. Arbeev, Liubov S. Arbeeva, Igor Akushevich, Svetlana V. Ukraintseva, Alexander M. Kulminski et al.
      Pages 263-284
    4. The Latent Class Stochastic Process Model for Evaluation of Hidden Heterogeneity in Longitudinal Data

      • Konstantin G. Arbeev, Kenneth C. Land, Anatoliy I. Yashin
      Pages 285-302
    5. Integrative Mortality Models with Parameters That Have Biological Interpretations

      • Anatoliy I. Yashin, Igor Akushevich, Konstantin G. Arbeev, Alexander M. Kulminski, Svetlana V. Ukraintseva
      Pages 321-330
    6. Integrative Mortality Models for the Study of Aging, Health, and Longevity: Benefits of Combining Data

      • Anatoliy I. Yashin, Igor Akushevich, Konstantin G. Arbeev, Alexander M. Kulminski, Svetlana V. Ukraintseva
      Pages 331-352

About this book

This volume is a critical exposition of the data and analyses from a full decade of rigorous research into how age-related changes at the individual level, along with other factors, contribute to morbidity, disability and mortality risks at the broader population level. After summarizing the state of our knowledge in the field, individual chapters offer enlightening discussion on a range of key topics such as age trajectory analysis in select and general populations, incidence/age patterns of major chronic illnesses, and indices of cumulative deficits and their use in characterizing and understanding the detailed properties of individual aging.


The book features comprehensive statistical analyses of unique longitudinal data sets including the unique resource of the Framingham Heart Study, with its more than 60 years of follow-up. Culminating in penetrating conclusions about the insights gained from the work involved, this book adds much to our understanding of the links between aging and human health.

Reviews

“A key strength of the book is the serious endeavor to go beyond traditional demographic approaches and incorporate more sophisticated mathematical analyses in the quest to integrate models for health, biology, and lifespan. A reasonable job is done of highlighting useful stochastic models for longitudinal data. Another positive is the variety and quality of the data used.” (Anthony Medford, Canadian Studies in Population, Vol. 46, 2019)




“The book is an effort to conciliate the empirical evidence that indicates that aging is a multidimensional process that involves changesin many variables, such as biomarkers. Thus, the book contributes at integrating biological knowledge and methods with traditional demographic analyses. Population scientists interested in population and biological mechanisms of aging will find this book valuable since it provides an overview of the most recent developments in the field.” (Vladimir Canudas-Romo and José Manuel Aburto, European Journal of Population, Vol. 33, 2017)

Authors and Affiliations

  • Biodemography of Aging Research Unit, Center for Population Health and Aging, Duke Population Research Institute & Social Science Research Institute, Duke University, Durham, USA

    Anatoliy I. Yashin, Eric Stallard, Kenneth C. Land

Bibliographic Information

Buy it now

Buying options

eBook USD 39.99
Price excludes VAT (USA)
  • Available as EPUB and PDF
  • Read on any device
  • Instant download
  • Own it forever
Softcover Book USD 54.99
Price excludes VAT (USA)
  • Compact, lightweight edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info
Hardcover Book USD 54.99
Price excludes VAT (USA)
  • Durable hardcover edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info

Tax calculation will be finalised at checkout

Other ways to access