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AIDS Pathogenesis

Part of the book series: Immunology and Medicine (IMME, volume 28)

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Table of contents (17 chapters)

  1. Front Matter

    Pages I-XI
  2. HIV-1 Transmission

    • Angélique Van’t Wout, Richard A. Koup, William A. Paxton
    Pages 1-17
  3. Primary HIV Infection

    • Andrew Carr, David A. Cooper
    Pages 19-40
  4. Biological Variability of HIV-1

    • Jan Albert, Maarten Koot
    Pages 41-54
  5. T-Cell Dynamics and Renewal in HIV-1 Infection

    • Dawn R. Clark, Katja C. Wolthers
    Pages 55-64
  6. Long-Term Non-Progressive HIV Infection

    • Susan Buchbinder, Eric Vittinghoff
    Pages 65-75
  7. Cytotoxic T Lymphocytes in HIV-1 Infection

    • M. R. Klein, S. H. Van der Burg, B. Autran
    Pages 77-98
  8. Mechanisms and in-vivo Significance of HIV-1 Neutralisation

    • Paul W. H. I. Parren, Dennis R. Burton, Quentin J. Sattentau
    Pages 99-132
  9. Opportunistic Infections

    • Jannik Helweg-Larsen, Thomas L. Benfield, Jens D. Lundgren
    Pages 155-176
  10. A — Aids-Related Non-Hodgkin’s Lymphomas

    • Marie José Kersten, M. H. J. Van Oers
    Pages 177-194
  11. Aids Dementia Complex

    • Peter Portegies, Roelien H. Enting
    Pages 209-220
  12. Anti-Retroviral Therapy and Resistance to Anti-Retroviral Drugs

    • Joep M. A. Lange, Julio S. G. Montaner
    Pages 221-242
  13. Prognostic Markers and Immunological Reconstitution During HIV-1 Infection

    • Marijke Th. L. Roos, Nadine G. Pakker, Peter Th. A. Schellekens
    Pages 243-259
  14. HIV Viral Load

    • Frank De Wolf, Ingrid Spijkerman
    Pages 261-272
  15. Back Matter

    Pages 283-283

About this book

Infection with the human immunodeficiency virus is characterized by the destruction of the host immune system as also reflected by a progressive loss of CD4-positive T-cells. This finally results in the host's incapacity to deal with opportunistic infections and the immune surveillance of tumors, a clinical status known as the Acquired Immunodeficiency Syndrome (AIDS).
The book AIDS Pathogenesis provides the reader with a complete overview of the clinical course of HIV-1 infection. It describes the clinical aspects of primary infection, the different clinical outcomes of HIV-1 infection, and strategies for anti-viral treatment. In addition, more fundamental aspects of HIV-1 infection are reviewed. These include the biology of the virus and the novel insights in AIDS pathogenesis. Not only is the significance of an HIV-specific cellular and humoral immune response discussed, but also the possible incapacity of the adult human host to deal with T-cell destruction. Finally, the book discusses the currently used laboratory markers that allow for monitoring of the clinical course of infection.

Editors and Affiliations

  • CLB and Laboratory for Experimental and Clinical Immunology, University of Amsterdam, Amsterdam, The Netherlands

    Hanneke Schuitemaker, Frank Miedema

Bibliographic Information

Buy it now

Buying options

eBook USD 129.00
Price excludes VAT (USA)
  • Available as EPUB and PDF
  • Read on any device
  • Instant download
  • Own it forever
Softcover Book USD 169.99
Price excludes VAT (USA)
  • Compact, lightweight edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info
Hardcover Book USD 169.99
Price excludes VAT (USA)
  • Durable hardcover edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info

Tax calculation will be finalised at checkout

Other ways to access