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Advances in Prostaglandin and Leukotriene Research

Basic Science and New Clinical Applications

  • Book
  • © 2001

Overview

Editors:
  1. Bengt Samuelsson

    1. Department of Medical Biochemistry and Biophysics, Division of Physiological Chemistry II, Karolinska Institute, Stockholm, Sweden

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  2. R. Paoletti

    1. Department of Pharmacological Sciences, University of Milan, Milan, Italy

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  3. Giancarlo C. Folco

    1. Department of Pharmacological Sciences, University of Milan, Milan, Italy
      Center for Cardiopulmonary Pharmacology, Institute of Pharmacological Sciences, University of Milan, Milan, Italy

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  4. E. Granström

    1. Karolinska Hospital, Stockholm, Sweden

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  5. S. Nicosia

    1. Department of Pharmacological Sciences, University of Milan, Milan, Italy

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Part of the book series: Medical Science Symposia Series (MSSS, volume 16)

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Table of contents (38 chapters)

  1. Front Matter

    Pages i-xxi
    Download chapter PDF

  2. Lipoxygenases and Leukotriene Biosynthesis

    1. Phosphorylation and Activation of 5-Lipoxygenase by P38 Kinase-Activated MAPKAP Kinases

      • Oliver Werz, Jenny Klemm, Olof Rådmark, Bengt Samuelsson
      Pages 1-7

    2. 5-Lipoxygenase and the Nucleus: Where, When, How, and Why?

      • Marc Peters-Golden, Thomas G. Brock
      Pages 9-15

    3. Calcium Binding Site of 5-Lipoxygenase

      • Tove Hammarberg, Patrick Provost, Konda Veera Reddy, Bengt Persson, Olof Rådmark
      Pages 17-20

    4. Regulation of Cellular 5-Lipoxygenase Activity by Glutathione Peroxidases

      • Dietlind Schumann, Oliver Werz, Dagmar Szellas, Dieter Steinhilber
      Pages 21-23

    5. Novel Aspects Related to Biosynthesis and Biological Actions of Hepoxilins: Interrelationship with Phospholipid Hydroperoxide Glutathione Peroxidase (PHGPx)

      • Pattabhiraman Shankaranarayanan, Mark Sutherland, Helmar Waiczies, Tankred Schewe, Santosh Nigam
      Pages 25-29

    6. Transcriptional Regulation of the Human Leukotriene C4 Synthase Promoter

      • Ji-liang Zhao, K. Frank Austen, Bing K. Lam
      Pages 31-36

    7. Localization and Translocation of Enzymes Involved in Leukotriene Biosynthesis

      • Yoshiyuki Ide, Hiromi Hanaka, Tetsuya Hirabayashi, Takao Shimizu, Takashi Izumi
      Pages 37-40

  3. Cyclooxygenases and Prostaglandin Biosynthesis

    1. Regulation of COX-2 Expression in Fibroblasts, Osteoblasts, Mast Cells, and Macrophages

      • Harvey R. Herschman, David J. Wadleigh, Srinivasa T. Reddy
      Pages 41-47

    2. Antimicroinflammatory Lipid Signals from Vascular Cyclooxygenase-2: A Novel Mechanism for NSAID and N-3 PUFA Therapeutic Actions

      • Charles N. Serhan, Clary B. Clish, Jessica Brannon, Sean P. Colgan, Karsten Gronert, Nan Chiang
      Pages 49-55

    3. Substrate Interactions in the Cyclooxygenase-1 Active Site

      • Elizabeth D. Thuresson, Michael G. Malkowski, Karen M. Lakkides, C. Jill Rieke, Ying Sun, Byron Wingerd et al.
      Pages 57-64

    4. Mutation of the Human Prostacyclin Synthase Gene

      • Tomohiro Nakayama, Masayoshi Soma, Duolikun Rehemudula, Katsuo Kanmatsuse
      Pages 65-68

    5. Structure and Function of Two Distinct Types of Prostaglandin D Synthase

      • Yoshihiro Urade, Osamu Hayaishi
      Pages 69-72

    6. Roles of Prostaglandin F Synthase

      • Kikuko Watanabe, Toshiko Suzuki-Yamamoto, Mikio Nishizawa, Motonari Fukui, Kazunori Ishimura, Seiji Ito
      Pages 73-76

    7. Differential Effects of Nitric Oxide on Cyclooxygenase 1 and 2 Activities in Cultured Cells

      • Sei-itsu Murota, Mitsue Onodera, Ikuo Morita
      Pages 77-80

  4. Phospholipase A2

    1. On the Functional Diversity of Secreted Phospholipases A2: Cloning of Novel Mammalian Enzymes and HIV-1 Antiviral Properties

      • Gérard Lambeau, Emmanuel Valentin, Rao Koduri, David Fenard, Alain Doglio, Michael Gelb et al.
      Pages 81-84

    2. Regulation of Cytosolic Phospholipase A2 by Phosphorylation

      • Michael H. Gelb, Ying Hefner, Angelika G. Börsch-Haubold, Steve P. Watson
      Pages 85-88

  5. Cytochrome P450 Archidonate Metabolites

    1. Synthesis and Function of 20-Hydroxyeicosatetraenoic Acid in the Kidney

      • Michal Laniado Schwartzman, Jackleen Marji, Miao Jiang, Mong-Heng Wang
      Pages 89-97

  6. Receptors

    1. Altered Bronchodilation and Pulmonary Inflammation in Prostanoid EP2 Receptor Knockout Mice

      • Francois Nantel, Danielle Denis, Simon Wong, Paul Masson, Denis Normandin, Maria Cirino et al.
      Pages 99-101

    2. Induction of Prostaglandin I2 Receptor in Murine Osteoblastic Cell

      • Kei Yamamoto, Jining Wang, Yukihiko Sugimoto, Atsushi Ichikawa, Shozo Yamamoto
      Pages 103-106
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Keywords

Editors and Affiliations

  • Department of Medical Biochemistry and Biophysics, Division of Physiological Chemistry II, Karolinska Institute, Stockholm, Sweden

    Bengt Samuelsson

  • Department of Pharmacological Sciences, University of Milan, Milan, Italy

    R. Paoletti, Giancarlo C. Folco, S. Nicosia

  • Center for Cardiopulmonary Pharmacology, Institute of Pharmacological Sciences, University of Milan, Milan, Italy

    Giancarlo C. Folco

  • Karolinska Hospital, Stockholm, Sweden

    E. Granström

Bibliographic Information

  • Book Title: Advances in Prostaglandin and Leukotriene Research

  • Book Subtitle: Basic Science and New Clinical Applications

  • Editors: Bengt Samuelsson, R. Paoletti, Giancarlo C. Folco, E. Granström, S. Nicosia

  • Series Title: Medical Science Symposia Series

  • DOI: https://doi.org/10.1007/978-94-015-9721-0

  • Publisher: Springer Dordrecht

  • eBook Packages: Springer Book Archive

  • Copyright Information: Springer Science+Business Media Dordrecht 2001

  • Hardcover ISBN: 978-1-4020-0146-8Published: 31 January 2002

  • Softcover ISBN: 978-90-481-5881-2Published: 04 December 2010

  • eBook ISBN: 978-94-015-9721-0Published: 09 March 2013

  • Series ISSN: 0928-9550

  • Edition Number: 1

  • Number of Pages: XXII, 206

  • Topics: Biochemistry, general, Human Physiology, Pharmacology/Toxicology, Pneumology/Respiratory System

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