On the Study and Practice of Intravenous Anaesthesia

1. Front Matter

   Pages i-xv

   PDF

2. Modelling of anaesthetic action: the effect site

   1. Front Matter

      Pages 1-1

      PDF

   2. Physiological Modelling and the Effect Site

      • Michael Weiss

      Pages 3-16

   3. Targeting the Effect Site

      • James G. Bovill

      Pages 17-26

   4. Effect Sites of Intravenous Anaesthetic Agents

      • Koji Morita, Tomiei Kazama, Shigehito Sato, Kazuyuki Ikeda

      Pages 27-43

   5. Exploring the Plasma-Effect Site Concentration Difference During Effect Site Controlled Infusion

      • Catherine Moiny, Edouard Coussaert, Luc Barvais

      Pages 45-58

   6. Genetic Models and Mapping Genes in the Study of Anaesthetic Action

      • Victoria J. Simpson, Brad Rikke, Elaine Shen, Beth Bennett, Yuri Blednov, Thomas Johnson

      Pages 59-67

3. The perioperative use of hypnotic agents

   1. Front Matter

      Pages 69-69

      PDF

   2. Total Intravenous Anaesthesia: The Equipment

      • Frank H. M. Engbers

      Pages 71-87

   3. Closed Loop Control of General Anaesthesia

      • Anthony Absalom, Gavin N. C. Kenny

      Pages 89-98

   4. The Effect of Opioids on the Pharmacokinetics and Pharmacodynamics of Propofol

      • Jaap Vuyk

      Pages 99-111

   5. Strategies to Prevent Awareness

      • Michel Struys, Eric Mortier, Linda Versichelen

      Pages 113-127

   6. Patient Controlled Sedation During Locoregional Anaesthesia

      • Nick Sutcliffe, Daniel Amutike

      Pages 129-144

   7. Target Controlled Sedation in the Intensive Care Unit

      • Sandra M. Groen-Mulder

      Pages 145-156

4. State of the art on neuromuscular blockade

   1. Front Matter

      Pages 157-157

      PDF

   2. Computer-Controlled Infusion of Neuromuscular Blocking Agents

      • Valérie Billard, Philippe Mavoungou

      Pages 159-172

   3. New Neuromuscular Blocking Agents and Fast-Tracking Anaesthesia

      • Hermann Mellinghoff, Christoph Diefenbach

      Pages 173-186

   4. Neuromuscular Blocking Agents in the Elderly

      • Frederique Servin

      Pages 187-193

   5. The Use of Neuromuscular Blocking Agents in the ICU

      • Karin S. Khünl-Brady

      Pages 195-206

   6. Neuromuscular Blocking Agents and Neuromuscular Diseases

      • Benoît Plaud, François Donati

      Pages 207-215

close circle of anaesthetic scientists but, with the help of computer technology, has greatly influenced the practice of the modern clinical anaesthesiologist. The efforts of anaesthesiologists, pharmaceutical companies, and the development of the internet has lead to a situation that now almost every anaesthesiologist can be in close contact to anaesthetic pharmacology computer simulation pro­ grams and target controlled infusion devices. These two tools allow us to in­ crease our understanding and improve the controllability of anaesthetic drug administration, on site, in the operating theatre. In Europe the growing enthusi­ asm regarding the study and practice of intravenous anaesthesia has lead to an increased output of manuscripts on this subject, the initiation of workshops on the pharmacology of anaesthetic agents and the formation of a society that embodies this spirit; the European Society for Intravenous Anaesthesia, the EuroSIVA. EuroSIVA The concept of EuroSIVA has been to provide a forum to co-ordinate, facilitate and promote high quality presentations in the area of intravenous drug admini­ stration. The first two meetings held in 1988 in Barcelona and 1999 in Amster­ dam achieved these aims. During the Barcelona and Amsterdam meetings pre­ senters of over 10 countries shared their knowledge with 250 and 400 partici­ pants, respectively. In addition to the EuroSIVA meetings the international board aims to promote education for those involved with intravenous anaes­ thesia.

• Infusion
• Opioid
• drug
• intensive care unit
• kinetics
• pain
• pain management
• pharmacodynamics
• pharmacokinetics
• pharmacology
• research
• serotonin

• Leiden University Medical Center, Leiden, The Netherlands

  Jaap Vuyk, Frank Engbers

• Leyenburg Hospital, The Hague, The Netherlands

  Sandra Groen-Mulder

Policies and ethics