Cardiovascular, Respiratory, Gastrointestinal and Genitourinary Malformations

1. Front Matter

   Pages i-ix

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2. Diagnosis of cardiovascular malformations

   • A. A. Shem-Tov

   Pages 1-5

3. Pathogenetic considerations of respiratory tract malformations in humans

   • B. H. Landing, T. R. Wells, L. G. Dixon

   Pages 7-54

4. Pulmonary sequestration

   • N. E. Wiseman, R. I. Macpherson

   Pages 55-73

5. Bronchogenic cyst

   • M. L. Ramenofsky

   Pages 75-89

6. Infantile hypertrophic pyloric stenosis: approaches to liability

   • J. C. Bear

   Pages 91-107

7. Congenital jejuno-ileal atresia and stenosis

   • S. Cywes, M. R. Q. Davies, H. Rode

   Pages 109-130

8. Omphalocoele and gastroschisis

   • J. A. Noordijk

   Pages 131-143

9. Urethral duplication

   • M. Gharib

   Pages 145-161

10. Uterine anomalies: clinical significance

    • R. E. Harris

    Pages 163-177

11. Congenital anomalies of the vagina

    • C. A. Salvatore

    Pages 179-199

12. Ambiguous genitalia in the newborn

    • P. K. Kottmeier

    Pages 201-216

13. Back Matter

    Pages 217-232

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Birth defects have assumed an importance even greater now than in the past because infant mortality rates attributed to congenital anomalies have declined far less than those for other causes of death, such as infectious and nutritional diseases. As many as 50 % of all pregnancies terminate as miscarriages, and in the majority of cases this is the result of faulty intrauterine development. Major congenital malformations are present in at least 2 % of all liveborn infants, and 22 % of all sti1Ibirths and infant deaths are associated with severe congenital anomalies. Not surprisingly, there has been a great proliferation of research into the problems of developmental abnormalities over the past few decades. This series, Advances in the Study of Birth Defects, was conceived in order to provide a comprehensive focal source of up-to-date information for physi­ cians concerned with the health of the unborn child and for research workers in the fields of fetal medicine and birth defects. The first four volumes featured recent experimental work on selected areas of high priority and intensive investigation, including mechanisms of teratogenesis, teratological evaluation, molecular and cellular aspects of abnormal development, and neural and behavioural teratology. It seems logical and timely that the clinical aspects should now be presented. Accordingly, leading experts were invited to review a broad range of common problems from the standpoint of embryology, aetiology, clinical manifestations, diagnosis and management. This volume deals with cardiovascular, respiratory, gastrointestinal, and genitourinary malformations.

• development
• embryo
• embryology
• nutrition

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