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Animal Cell Technology

From Vaccines to Genetic Medicine

  • Book
  • © 1997

Overview

Editors:
  1. Manuel J. T. Carrondo

    1. IBET, Oeiras, Portugal

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  2. Bryan Griffiths

    1. CAMR, Porton Down, Wiltshire, UK

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  3. José L. P. Moreira

    1. IBET, Oeiras, Portugal

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Table of contents (128 chapters)

  1. Front Matter

    Pages i-xviii
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  3. Cells and Vectors for Genetic Medicine

    1. Front Matter

      Pages 27-27
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    2. Polymer Encapsulated Xenogeneic Cell Lines: A Novel Approach for Gene Therapy

      • P. Aebischer
      Pages 29-31

    3. Gene Therapy and Genetic Vaccination: Two Hallmarks of Genetic Medicine

      • Dalemans Wilfried
      Pages 33-35

    4. PCR Detection of Murine Retroviruses and Characterization of a New Xenotropic Retrovirus from Myeloma Cells

      • Manfred Wirth, Thomas Heinemeyer, Lorin Schumacher, Andreas Klingenhoff, Wiebke Hansen, Zoltan Suemeghy et al.
      Pages 37-42

    5. Toward a DNA Vaccine Against Lyssa Viruses

      • C. Bahloul, F. Fouque, N. Tordo, Y. Jacob, P. Perrin
      Pages 43-46

    6. Principles of a Scaleable Transient Transfection and Expression Technology for Mammalian Cells

      • Martin Jordan, Christiane KÖhne, Florian M. Wurm
      Pages 47-50

    7. Neurological Therapy — Adenovirus Mediated Gene Therapy in Cells of the Central Nervous System

      • S. D. Sivasubramaniam, A. R. Fooks, J. Lee, G. Stacey, A. D. Jennings
      Pages 51-56

    8. Bovine Polyoma Virus Detection by Routine PCR Screening

      • Joanne Proffitt, Keri Jarvis, Carl Martin
      Pages 57-62

  4. Animal Cells as Tools for Discovery and Testing

    1. Front Matter

      Pages 63-63
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    2. Mammalian Cells in High Throughput Screening

      • William Janzen
      Pages 65-71

    3. Metabolism and Toxicological Studies in Immortalised Rat Hepatocyte Cell Lines

      • C. MacDonald, F. Reid, K. Anderson, L. Yin, E. Hill, H. Kelly et al.
      Pages 73-78

    4. Cell Based Assays for Drug Screening

      • Elizabeth Keenan, Helen Kruger, Balwinder Sambi, John S. McLean
      Pages 79-84

    5. Development of Drug Metabolism Simulator Using Three-Dimensional Culture of Hepatocytes of Rats and Dogs

      • Kazumori Funatsu, Kohji Nakazawa, Hiroshi Mizumoto, Kenji Takenaka, Taku Matsushita
      Pages 85-90

    6. Immobilization of Primary Brain Cells in Porous Microcarriers for on Line NMR Spectroscopy

      • P. M. Alves, M. J. T. Carrondo, H. Santos
      Pages 91-98

    7. Application of primary hepatocyte sandwich cultures for predictive studies of drug metabolism and precarcinogen activation

      • A. Bader, R. Fahrig, A. Steinkamp, N. Frühauf, O. Crome, K. Zech et al.
      Pages 99-102
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Keywords

About this book

Animal cell technology has undergone a rapid transformation over the last decade from a research tool and highly specialised technology to a central resource for innovation in pharmaceutical research and development. These proceedings of the 14th Meeting of the European Society for Animal Cell Technology (Vilamoura, Portugal, May 1996) bring up to date the historical perspective of animal cell technology for the benefit of society, `From Vaccines to Genetic Medicine', and will charter this vital technology for the years to come.
Strong contributions are grouped in the traditional ESACT areas of 'Cell and Physiology Engineering' dealing with cell state, including genetics, and its environment, and 'Animal Cell Process Engineering' covering integration of bioreaction with bioseparation coupled with on-line monitoring to improve protein production and consistency. Extensive coverage of metabolic engineering on synthesis, folding, assembly, transiting and secretion is dealt with in the session on 'Recombinant Proteins: Biosynthesis and Bioprocessing'. Two traditional but expanding areas of animal cell technology relevance are highlighted in the broad sessions of 'Animal Cells as Tools for Discovery and Testing' and 'Animal Cell Vaccines: Present and Future'. Two sessions finally cover the more recent domains of animal cell technology work - 'Tissue Engineering and Biomedical Devices' and 'Cells and Vectors for Genetic Medicine' - where one can foresee a very bright future.

Editors and Affiliations

  • IBET, Oeiras, Portugal

    Manuel J. T. Carrondo, José L. P. Moreira

  • CAMR, Porton Down, Wiltshire, UK

    Bryan Griffiths

Bibliographic Information

  • Book Title: Animal Cell Technology

  • Book Subtitle: From Vaccines to Genetic Medicine

  • Editors: Manuel J. T. Carrondo, Bryan Griffiths, José L. P. Moreira

  • DOI: https://doi.org/10.1007/978-94-011-5404-8

  • Publisher: Springer Dordrecht

  • eBook Packages: Springer Book Archive

  • Copyright Information: Kluwer Academic Publishers 1997

  • Hardcover ISBN: 978-0-7923-4321-9Published: 31 December 1996

  • Softcover ISBN: 978-94-010-6273-2Published: 05 October 2013

  • eBook ISBN: 978-94-011-5404-8Published: 06 December 2012

  • Edition Number: 1

  • Number of Pages: XVIII, 816

  • Topics: Animal Anatomy / Morphology / Histology, Pharmacy, Biotechnology, Industrial Chemistry/Chemical Engineering

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