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The Immunoglobulin Receptors and their Physiological and Pathological Roles in Immunity

  • Book
  • © 1998

Overview

Editors:
  1. Jan G. J. Winkel

    1. Utrecht University, Utrecht, The Netherlands

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    You can also search for this editor in PubMed   Google Scholar

  2. P. Mark Hogarth

    1. Austin Research Institute, Melbourne, Australia

    View editor publications

    You can also search for this editor in PubMed   Google Scholar

Part of the book series: Immunology and Medicine (IMME, volume 26)

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Table of contents (27 chapters)

  1. Front Matter

    Pages i-xv
    Download chapter PDF

  2. Introduction to the field

    1. Introduction to the field

      • W. H. Fridman
      Pages 1-7

  3. Physiological Role of Fc Receptors

    1. Front Matter

      Pages 9-9
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    2. General aspects of FcR

      1. Molecular basis for the interaction of Fc receptors with immunoglobulins
        • A. Gavin, M. Hulett, P. M. Hogarth
        Pages 11-35
      2. Fc receptor genetics and the manipulation of genes in the study of FcR biology
        • T. Takai, J. V. Ravetch
        Pages 37-48
      3. Commentary
        • R. G. Lynch
        Pages 49-50

    4. FcR and cell activation

      1. Signals initiated by the high affinity FcR for IgE
        • O. H. Choi, P. G. Holbrook
        Pages 83-93
      2. Phagocyte Fc receptors for IgG
        • S. E. Mckenzie, Z. K. Indik, A. D. Schreiber
        Pages 95-107
      3. Human IgA Fc receptors (FcαR)
        • H. C. Morton, M. van Egmond, J. G. J. van de Winkel
        Pages 109-117
      4. Platelet Fc receptors for IgG and IgE
        • A. Greinacher
        Pages 119-134
      5. Polymorphisms of FcγRIIIa on NK cells and macrophages
        • H. R. Koene, A. E. G. Kr. Von Dem Borne, D. Roos, M. de Haas
        Pages 135-140
      6. Cooperation between IgG Fc receptors and complement receptors in host defence
        • E. J. Brown
        Pages 141-149
      7. Commentary
        • H. Metzger
        Pages 151-154

    5. FcR and immunoregulation

      1. FcγR and IgG-mediated negative regulation of immune responses
        • M. Daëron, B. Heyman
        Pages 155-167
      2. FcγR on T cells
        • M. Sandor, R. G. Lynch
        Pages 169-183
      3. Role of IgG and IgE FcR in antigen presentation
        • P. M. Guyre, J. K. O’Shea
        Pages 185-194
      4. Structure and function of CD23
        • D. H. Conrad
        Pages 195-206
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Keywords

About this book

Antibodies are crucial to the fine specificity of the immune system. An effective functioning of these molecules requires interaction with immune cells. Receptors for antibodies, Fc receptors, provide this critical link between the humoral and cellular branches of the immune system. This book presents a comprehensive overview of the different Fc receptors currently recognized. The first part of the book contains state-of-the-art overviews on the biological role of FcR. The latest information on FcR heterogeneity, FcR physiology, FcR-ligand recognition, their crucial coordinating role in immunity, interactions with other immunoreceptors, and the role of FcR in immunoglobulin transport and catabolism are discussed. The clinical importance of FcR is developed in the second part of the book. The well-recognized roles of FcR in allergy, inflammation, infectious diseases, autoimmune disorders, and immunotherapeutic importance are reviewed. The information in this book is easily accessible and should be helpful for researchers and clinical specialists as a convenient overview of the field, as well as a comprehensive introduction for students starting in this area of research.

Editors and Affiliations

  • Utrecht University, Utrecht, The Netherlands

    Jan G. J. Winkel

  • Austin Research Institute, Melbourne, Australia

    P. Mark Hogarth

Bibliographic Information

  • Book Title: The Immunoglobulin Receptors and their Physiological and Pathological Roles in Immunity

  • Editors: Jan G. J. Winkel, P. Mark Hogarth

  • Series Title: Immunology and Medicine

  • DOI: https://doi.org/10.1007/978-94-011-5018-7

  • Publisher: Springer Dordrecht

  • eBook Packages: Springer Book Archive

  • Copyright Information: Springer Science+Business Media Dordrecht 1998

  • Hardcover ISBN: 978-0-7923-5021-7Published: 31 August 1998

  • Softcover ISBN: 978-94-010-6106-3Published: 11 October 2012

  • eBook ISBN: 978-94-011-5018-7Published: 02 February 2012

  • Edition Number: 1

  • Number of Pages: XV, 324

  • Topics: Immunology, Infectious Diseases, Allergology, Biochemistry, general, Rheumatology

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