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Copper and Zinc in Inflammatory and Degenerative Diseases

  • Book
  • © 1998

Overview

Editors:
  1. K. D. Rainsford

    1. Division of Biomedical Sciences, School of Science and Mathematics, Sheffield Hallam University, Sheffield, UK

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  2. R. Milanino

    1. Institute of Pharmacology, University of Verona, Verona, Italy

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  3. J. R. J. Sorenson

    1. Department of Pharmacy, University of Arkansas for Medical Science Campus, Little Rock, USA

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  4. G. P. Velo

    1. Institute of Pharmacology, University of Verona, Verona, Italy

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Table of contents (13 chapters)

  1. Front Matter

    Pages i-ix
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  2. History of zinc therapy

    • T. U. Hoogenraad
    Pages 1-5

  3. Physiological properties of copper and zinc

    • V. Albergoni
    Pages 7-17

  4. Biological chemistry of copper compounds

    • L.-O. Klotz, U. Weser
    Pages 19-46

  5. The biological chemistry of zinc

    • S. Rahuel-Clermont, M. F. Dunn
    Pages 47-59

  6. Copper and zinc metallothioneins

    • V. Albergoni, E. Piccinni
    Pages 61-78

  7. Zinc in the regulation and therapy of inflammatory diseases and gastrointestinal ulceration

    • K. D. Rainsford, B. Zeitlin
    Pages 79-111

  8. Copper complexes for therapy of cancer and autoimmune diseases

    • J. R. J. Sorenson
    Pages 113-124

  9. Zinc and copper in the treatment of rheumatic diseases

    • F. Fernández-Madrid
    Pages 125-137

  10. Topically applied copper preparations for anti-inflammatory therapy

    • S. J. Beveridge
    Pages 139-146

  11. Regulation by copper of rat adjuvantarthritis: a model of chronic inflammation especially suitable for studying the mechanisms of copper anti-inflammatory activity

    • R. Milanino, M. Marrella, G. P. Velo, P. Cristofori, A. Terron
    Pages 147-159

  12. Copper and zinc compounds and cell surface interactions

    • M. E. Davies, M. Pasqualicchio
    Pages 161-172

  13. Copper and postmenopausal osteoporosis

    • J. J. Strain
    Pages 173-178

  14. Menkes disease: a genetic defect of copper transport

    • B. Sarkar
    Pages 179-187

  15. Back Matter

    Pages 189-197
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Keywords

About this book

Abnormal metabolism and distribution of both copper and zinc occurs in many inflammatory and degenerative diseases. The pattern of these changes varies at different stages of these diseases and with differing types of conditions. The corollary to this situation is the possibility of using drugs or metal complexes to modify both the perturbed status of copper and zinc and thus the disease states.
This book comprehensively reviews the clinical and experimental data on the changes in copper and zinc status in different diseases and the use of various complexes of these metals or drugs to treat a diversity of inflammatory and degenerative conditions.

Editors and Affiliations

  • Division of Biomedical Sciences, School of Science and Mathematics, Sheffield Hallam University, Sheffield, UK

    K. D. Rainsford

  • Institute of Pharmacology, University of Verona, Verona, Italy

    R. Milanino, G. P. Velo

  • Department of Pharmacy, University of Arkansas for Medical Science Campus, Little Rock, USA

    J. R. J. Sorenson

Bibliographic Information

  • Book Title: Copper and Zinc in Inflammatory and Degenerative Diseases

  • Editors: K. D. Rainsford, R. Milanino, J. R. J. Sorenson, G. P. Velo

  • DOI: https://doi.org/10.1007/978-94-011-3963-2

  • Publisher: Springer Dordrecht

  • eBook Packages: Springer Book Archive

  • Copyright Information: Springer Science+Business Media Dordrecht 1998

  • Hardcover ISBN: 978-0-7923-4827-6Published: 28 February 1998

  • Softcover ISBN: 978-94-010-5757-8Published: 13 October 2012

  • eBook ISBN: 978-94-011-3963-2Published: 06 December 2012

  • Edition Number: 1

  • Number of Pages: IX, 197

  • Topics: Gastroenterology, Biochemistry, general

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