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Modern Aspects of Protein Adsorption on Biomaterials

  • Book
  • © 1991

Overview

Editors:
  1. Y. F. Missirlis

    1. Laboratory of Biomedical Engineering, University of Patras, Patras, Greece

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  2. W. Lemm

    1. Rudolf Virchow Clinic, Berlin 19, Germany

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    You can also search for this editor in PubMed   Google Scholar

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Table of contents (20 chapters)

  1. Front Matter

    Pages i-x
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  2. Methods and Techniques to Study the blood proteins — artificial surfaces interactions

    1. Front Matter

      Pages 1-1
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    2. Can protein adsorption studies using radioisotopic techniques be useful for the development of hemocompatible materials?

      • Ch. Baquey, F. Lespinasse, J. Caix, A. Baquey, B. Basse-Chathalinat
      Pages 3-18

    3. Competitive adsorption of proteins on polymer films: In situ measurements

      • A. Baszkin
      Pages 19-23

    4. Protein adsorption and the interaction of human endothelial cells with polymer surfaces

      • A. Dekker, T. Beugeling
      Pages 25-28

    5. Protein adsorption in relation to platelet adhesion and contact activation

      • A. A. Poot, T. Beugeling
      Pages 29-38

    6. Studies of protein adsorption relevant to blood compatible materials

      • J. L. Brash
      Pages 39-47

    7. Methods to study blood-surface interactions

      • J. P. Cazenave, J. N. Mulvihill
      Pages 49-53

    8. Protein adsorption at polymer-liquid interfaces using series of polymers with varying hydrophilicity, charge and chain mobility

      • H. S. Van Damme, J. Feijen
      Pages 55-61

    9. Cooperative protein adsorption on surfaces with controlled alkyl-residue lattices

      • H. P. Jennissen
      Pages 63-71

    10. Protein adsorption tests for polymer surfaces

      • W. Lemm
      Pages 73-79

    11. Advantages and problems using FT-IR spectroscopy to study blood-surface interactions by monitoring the protein adsorption process

      • A. Magnani, M. C. Roncolini, R. Barbucci
      Pages 81-86

    12. Biocompatibility research at Humboldt University

      • H. Wolf
      Pages 87-91

  3. Discussion Chapters

    1. Front Matter

      Pages 93-93
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    2. Protein characterization

      • Y. F. Missirlis, W. Lemm
      Pages 95-111

    3. Labelling and protein identification techniques

      • Y. F. Missirlis, W. Lemm
      Pages 113-135

    4. Problems of protein adsorption studies — Lyman hypothesis

      • Y. F. Missirlis, W. Lemm
      Pages 137-148

    5. Polymer surface properties

      • Y. F. Missirlis, W. Lemm
      Pages 149-161

    6. In vitro, in vivo or ex vivo studies

      • Y. F. Missirlis, W. Lemm
      Pages 163-168

    7. Kinetics of protein adsorption

      • Y. F. Missirlis, W. Lemm
      Pages 169-199
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Keywords

About this book

The present book relates to the scientific records of a workshop held in Patras, Greece, in June 1989, under the auspices and with financial support of the European Economic Communities (Concerted Action EUROBIOMAT - Hemocompatibility - of the Medical Research Programme, Project: 11.1.212). This concerted action promotes the collaboration on science and technology on the particular field of hemocompatible biomaterials: exchange of experts, scholarships and scientific workshops within the EC-member countries and COST countries such as Sweden, Finland, Turkey, Switzerland. The first part of this monography refers to the oral presentations of the par­ ticipants. The second part gives the book its unique character: the scientific discussion on updated aspects of protein adsorption of synthetic polymers in contact with blood. This second part is subdivided into nine chapters where specific topics were discussed freely, open-minded and even controversially. This book intends to elucidate recurrent questions concerning the initial event when blood contacts artificial surfaces. Young investigators will consider this book to be appropriate to get familiar with the scientific background and the most relevant techniques and methods.

Editors and Affiliations

  • Laboratory of Biomedical Engineering, University of Patras, Patras, Greece

    Y. F. Missirlis

  • Rudolf Virchow Clinic, Berlin 19, Germany

    W. Lemm

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