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  • Book
  • © 1990

Amino Acids

Chemistry, Biology and Medicine

Editors:

  1. Gert Lubec

    1. Department of Pediatrics, University of Vienna, Vienna, Austria

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    You can also search for this editor in PubMed   Google Scholar

  2. Gerald A. Rosenthal

    1. T. H. Morgan School of Biological Sciences and The Graduate Center for Toxicology, University of Kentucky, Lexington, USA

    View editor publications

    You can also search for this editor in PubMed   Google Scholar

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Table of contents (147 chapters)

  1. Front Matter

    Pages i-xx
    PDF

  2. Basic chemistry, Analysis and Synthesis

    1. Front Matter

      Pages 1-1
      PDF

    2. Novel amino acids from plants

      • Leslie Fowden
      Pages 3-9

    3. Chirospecific synthesis of amino acids and analogues

      • Tomihisa Ohta, Akio Hosoi, Toshihiko Kimura, Nobuaki Sato, Kunisuke Izawa, Shigeo Nozoe
      Pages 10-20

    4. Toxic and non-toxic nonprotein amino acids in the Vicieae

      • Fernand Lambein, Yu-Haey Kuo, Fumio Ikegami, Isamu Murakoshi
      Pages 21-28

    6. Chemistry of glutamate analogues

      • Haruhisa Shirahama, Kimiko Hashimoto, Miwa Yanagida, Manabu Horikawa
      Pages 39-46

    7. A simple conversion of tryptophan to a yohimbane derivative

      • Eugène Neuzil, Eliane de Tinguy-Moreaud, Gilles Précigoux, Nguyen Ba Chanh, Christian Courseille
      Pages 47-55

    9. 13C-Leucine-Tracer-Technique in clinical research on postoperative protein metabolism

      • H. J. Günther, W. Park, H. Paust, P. Scigalla, V. Schenkelberger, I. Reichardt et al.
      Pages 64-70

    15. Chemo-enzymatic synthesis of enantiomerically pure α-H and α-alkyl α-amino acids and derivatives

      • J. Kamphuis, H. F. M. Hermes, J. A. M. van Balken, H. E. Schoemaker, W. H. J. Boesten, E. M. Meijer
      Pages 119-125

    16. Synthesis of 11C-labelled amino acids

      • G. Antoni, P. Bjurling, K. J. Fasth, A. Gee, B. LÃ¥ngström
      Pages 126-133

    17. Chemoenzymatic syntheses of enantiomerically pure hydroxy amino acids

      • H. Hönig, P. Seufer-Wasserthal, H. Weber
      Pages 134-142

    18. Amino acid analysis by derivatization with o-phthaldialdehyde and chiral thiols

      • Hans Brückner, Robert Wittner, Herbert Godel
      Pages 143-151

    19. Chiral ligand-exchange chromatography of amino acid derivatives

      • Hans Brückner, Barbara Sorsche, Ali Esna-Ashari, Rolf Jöster
      Pages 152-158
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About this book

There is little wonder in the fact that the investigation of amino acids is of fundamental interest to scientists from so many diversified fields. If amino acids were only basic constituents of enzymes as well as structural and other proteins, this property alone would elevate them to real scientific importance. Added to this role, however, is their ability to serve as building blocks for the production of many classes of secondary metabolites. They can support the biosynthesis of a myriad of natural products including nonprotein amino acids, cyanogenic glycosides, phar­ macologically active alkaloids, certain phenols, purines and pyrimidines, nucleic acids, condensed tannins, lignins and other metabolites. The approximately twenty or so amino (and imino) acids that comprise proteins are well known; less familiar are what is now approaching 600 nonprotein amino acids that have been isolated and characterized from plant, fungal or animal sources. Investigations of the protein amino acids have proven of outstanding value in enhancing our understanding of a variety of physiological and neurological topics that affect human health and well being. Amino acids are used to probe inhibitory and excitatory transmission receptors in the brain. They contribute to our understanding of epilepsy, development of anti-epileptic drugs, production of novel y-arninobutyric acid uptake inhibitors, and acute and chronic neurodegenera­ tive disorders.
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Keywords

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Editors and Affiliations

  • Department of Pediatrics, University of Vienna, Vienna, Austria

    Gert Lubec

  • T. H. Morgan School of Biological Sciences and The Graduate Center for Toxicology, University of Kentucky, Lexington, USA

    Gerald A. Rosenthal

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Buy it now

eBook USD 74.99
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  • Available as PDF
  • Read on any device
  • Instant download
  • Own it forever

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